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Protein

Palmitoyltransferase

Gene

CG17196

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG17196Imported, Dmel_CG17196Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039368. CG17196.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 48HelicalUniRule annotationAdd BLAST23
Transmembranei54 – 76HelicalUniRule annotationAdd BLAST23
Transmembranei147 – 168HelicalUniRule annotationAdd BLAST22
Transmembranei193 – 213HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9VBM6.
PRIDEiQ9VBM6.

Expressioni

Gene expression databases

BgeeiFBgn0039368.
ExpressionAtlasiQ9VBM6. differential.
GenevisibleiQ9VBM6. DM.

Interactioni

Protein-protein interaction databases

MINTiMINT-1643652.
STRINGi7227.FBpp0084296.

Structurei

3D structure databases

SMRiQ9VBM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 228zf-DHHCInterPro annotationAdd BLAST126

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiQ9VBM6.
OMAiNDWCREY.
OrthoDBiEOG091G0RWR.
PhylomeDBiQ9VBM6.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VBM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIVNDWCRE YANLYPKKAV SIGHPLSVIF LLVSTVFFFT LQVFYVAPDV
60 70 80 90 100
HDGFMYKFFV ISAIFTTYNI LGNLLACYRT SSAVKSLPQE RQIPKPGTEH
110 120 130 140 150
LWHYCDICQK LMPPRSWHCA LCKCCILKRD HHCIFAATCI GHNNHRYFFW
160 170 180 190 200
LTFYLAFGIF MSMATLFVDV GRSFYLLHRM KAGFGNTVKS LSYFRYVCLI
210 220 230 240 250
LNIFALGFPA LMLRFQVQIL KLNSTYYQIS SRHHDLGFRN NCQLIMGQRG
260 270
LWTFISPSLR SPLPHDGTHW KIKQCF
Length:276
Mass (Da):32,196
Last modified:May 1, 2000 - v1
Checksum:i7589B6817FA28104
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56504.1.
RefSeqiNP_651426.1. NM_143169.3.

Genome annotation databases

EnsemblMetazoaiFBtr0084922; FBpp0084296; FBgn0039368.
GeneIDi43112.
UCSCiCG17196-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56504.1.
RefSeqiNP_651426.1. NM_143169.3.

3D structure databases

SMRiQ9VBM6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1643652.
STRINGi7227.FBpp0084296.

Proteomic databases

PaxDbiQ9VBM6.
PRIDEiQ9VBM6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0084922; FBpp0084296; FBgn0039368.
GeneIDi43112.
UCSCiCG17196-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0039368. CG17196.

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiQ9VBM6.
OMAiNDWCREY.
OrthoDBiEOG091G0RWR.
PhylomeDBiQ9VBM6.

Miscellaneous databases

GenomeRNAii43112.

Gene expression databases

BgeeiFBgn0039368.
ExpressionAtlasiQ9VBM6. differential.
GenevisibleiQ9VBM6. DM.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VBM6_DROME
AccessioniPrimary (citable) accession number: Q9VBM6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 12, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.