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Protein

Palmitoyltransferase

Gene

CG17195

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG17195Imported, Dmel_CG17195Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039369. CG17195.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 46HelicalUniRule annotationAdd BLAST25
Transmembranei58 – 79HelicalUniRule annotationAdd BLAST22
Transmembranei147 – 171HelicalUniRule annotationAdd BLAST25
Transmembranei205 – 224HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0039369.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0084295.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 235DHHCInterPro annotationAdd BLAST133

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
KOiK18932.
OMAiACYMTSS.
OrthoDBiEOG091G0RWR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VBM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCYVNRFCHY FANRYPKNFV RIVHPLSIVF VLCSTAFFFS LQMFYIAPKV
60 70 80 90 100
FGDIAYKLYW ILVTFITHNI LGNMLACYMT SSSVNTLSKD SRCPNPEDEP
110 120 130 140 150
LWHYCESCKK LRSPRSWHCV LCNTCILRRD HHCIFTGTCI GHNNQRFFFW
160 170 180 190 200
FTFYLTLGLV TSFATFCMFI LQNGGNFMSL SSVIFNLITR TFFQNYTGNT
210 220 230 240 250
FETIAFLLNI SASYMPAFML AYQMQILSQN STYYNIFDCT YDLGFRKNCQ
260 270 280
TIMGQRGLWT FISPLLKSPL PHDGAHWQMK QSH
Length:283
Mass (Da):33,147
Last modified:February 7, 2006 - v2
Checksum:iC5571F3E47BA2D2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56505.2.
BT022183 mRNA. Translation: AAY51577.1.
RefSeqiNP_651427.2. NM_143170.2.
UniGeneiDm.25011.

Genome annotation databases

EnsemblMetazoaiFBtr0084921; FBpp0084295; FBgn0039369.
GeneIDi43113.
KEGGidme:Dmel_CG17195.
UCSCiCG17195-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9VBM5_DROME
AccessioniPrimary (citable) accession number: Q9VBM5
Secondary accession number(s): Q4V6X3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: February 7, 2006
Last modified: July 5, 2017
This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported