Unreviewed, UniProtKB/TrEMBL Q9VB22 (Q9VB22_DROME)

Names and origin

Protein names

Submitted name:
    Rapsynoid EMBL AAF56721.1
Submitted name:
    LD33695p EMBL AAM11170.1
    Pins protein EMBL AAF64499.1
    RE22964p EMBL AAO39527.1

Gene names

Name:	raps EMBL AAF56721.1 FlyBase FBgn0040080
Synonyms:	pins EMBL AAF64499.1
ORF Names:	CG5692 FlyBase FBgn0040080, Dmel_CG5692 EMBL AAF56721.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	Repeat RuleBase RU003537V0 TPR repeat RuleBase RU003339V0
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asymmetric cell division Inferred from mutant phenotype. Source: FlyBase asymmetric neuroblast division Inferred from mutant phenotype. Source: FlyBase asymmetric protein localization involved in cell fate determination Traceable author statement. Source: FlyBase basal protein localization Traceable author statement. Source: FlyBase establishment of mitotic spindle orientation Inferred from mutant phenotype. Source: FlyBase maintenance of protein location Non-traceable author statement. Source: FlyBase neuroblast fate determination Traceable author statement. Source: FlyBase signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	apical cortex Inferred from direct assay. Source: FlyBase
Molecular function	GTPase activator activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VB22-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 5D24B15B4FAE584F	FASTA	658	71,469
	10 20 30 40 50 60 MSSLSASAEN VSSLGLGSGG GGTTSHDGNS QQGSGSDGGS SMCLELALEG ERLCKAGDCR 70 80 90 100 110 120 AGVAFFQAAI QAGTEDLRTL SAIYSQLGNA YFYLGDYNKA MQYHKHDLTL AKSMNDRLGE 130 140 150 160 170 180 AKSSGNLGNT LKVMGRFDEA AICCERHLTL ARQLGDRLSE GRALYNLGNV YHAKGKHLGQ 190 200 210 220 230 240 RNPGKFGDDV KEALTRAVEF YQENLKLMRD LGDRGAQGRA CGNLGNTYYL LGDFQAAIEH 250 260 270 280 290 300 HQERLRIARE FGDRAAERRA NSNLGNSHIF LGQFEDAAEH YKRTLALAVE LGEREVEAQS 310 320 330 340 350 360 CYSLGNTYTL LHEFNTAIEY HNRHLAIAQE LGDRIGEARA CWSLGNAHSA IGGHERALKY 370 380 390 400 410 420 AEQHLQLAKE LHDPVGESTA RVNISDLRKL LGMPDSEPSP TEEEARSTAS DHSASGNQSD 430 440 450 460 470 480 GSENSQGRMV RVRRQSMEQL DLIKITPDGK RMQEEKLRAQ ATRKAKDDDF FEMLSRSQSK 490 500 510 520 530 540 RMDDQRCSIK VNPAGAPAVA TGATRKPLVQ QNSLFVDPTN LPGLKSPSSA NPSAIGHGPL 550 560 570 580 590 600 ARSATTTQQP DDDFLDMLMR CQGSRLEEQR SELPRPNVTM DAEAEAPPRS VPEAAVPGAP 610 620 630 640 650 RGQTGRGATV PDEDFFSLIM KVQSGRMEDQ RASIPFRNAN NNNNSRSNNN GSAGGAGK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAO39527.1.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM11170.1.
[5]	"A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila." Schaefer M., Shevchenko A., Knoblich J.A. Curr. Biol. 10:353-362(2000) [PubMed: 10753746] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF56721.1. AF242203 mRNA. Translation: AAF64499.1. AY094817 mRNA. Translation: AAM11170.1. BT003523 mRNA. Translation: AAO39527.1.
RefSeq	NP_524999.2.
UniGene	Dm.7372
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VB22. 35 interactions.
Proteomic databases
PRIDE	Q9VB22.
Genome annotation databases
Ensembl	FBgn0040080. Drosophila melanogaster. [Contig view]
GeneID	53569.
KEGG	dme:Dmel_CG5692.
NMPDR	fig|7227.3.peg.15001.
Organism-specific databases
FlyBase	FBgn0040080. raps.
Phylogenomic databases
OMA	Q9VB22. DDQRCSI.
Gene expression databases
ArrayExpress	Q9VB22.
Family and domain databases
InterPro	IPR003109. GoLoco_motif. IPR001440. TPR-1. IPR011990. TPR-like_helical. IPR013026. TPR_region. IPR019734. TPR_repeat. [Graphical view]
Gene3D	G3DSA:1.25.40.10. TPR-like_helical. 2 hits.
Pfam	PF02188. GoLoco. 3 hits. PF00515. TPR_1. 7 hits. [Graphical view]
SMART	SM00390. GoLoco. 3 hits. SM00028. TPR. 7 hits. [Graphical view]
PROSITE	PS50877. GOLOCO. 3 hits. PS50005. TPR. 5 hits. PS50293. TPR_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	841431.

Entry information

Entry name

Q9VB22_DROME

Accession

Primary (citable) accession number: Q9VB22

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)