Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9VAT0 (Q9VAT0_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 121. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length527 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains CRIB domain. SAAS SAAS000095

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processArp2/3 complex-mediated actin nucleation

Inferred from direct assay PubMed 19633175. Source: FlyBase

apical constriction

Inferred from mutant phenotype PubMed 19934015. Source: FlyBase

asymmetric cell division

Traceable author statement PubMed 15196561. Source: FlyBase

axonal fasciculation

Inferred from genetic interaction PubMed 11854309. Source: FlyBase

axonogenesis

Inferred from genetic interaction PubMed 11854309. Source: FlyBase

cell competition in a multicellular organism

Inferred from mutant phenotype PubMed 17574031. Source: FlyBase

cell fate commitment

Traceable author statement PubMed 15196561. Source: FlyBase

chaeta morphogenesis

Inferred from mutant phenotype PubMed 11854309. Source: FlyBase

clathrin-mediated endocytosis

Inferred from mutant phenotype PubMed 17014698. Source: FlyBase

cuticle pattern formation

Inferred from mutant phenotype PubMed 16933974. Source: FlyBase

epidermal cell differentiation

Inferred from mutant phenotype PubMed 16933974. Source: FlyBase

intracellular protein transport

Inferred from mutant phenotype PubMed 19543274. Source: FlyBase

membrane budding

Inferred from mutant phenotype PubMed 17014698. Source: FlyBase

microtubule bundle formation

Inferred from direct assay PubMed 19633175. Source: FlyBase

muscle attachment

Inferred from mutant phenotype PubMed 17306790. Source: FlyBase

myoblast fusion

Inferred from mutant phenotype PubMed 17306790PubMed 17419994PubMed 21098115. Source: FlyBase

negative regulation of synaptic growth at neuromuscular junction

Inferred from mutant phenotype PubMed 14980202PubMed 21041451. Source: FlyBase

positive regulation of Arp2/3 complex-mediated actin nucleation

Inferred from electronic annotation. Source: InterPro

regulation of actin filament polymerization

Inferred from mutant phenotype PubMed 19934015PubMed 21652648. Source: FlyBase

regulation of embryonic cell shape

Inferred from mutant phenotype PubMed 19934015. Source: FlyBase

regulation of synaptic growth at neuromuscular junction

Inferred from direct assay PubMed 20554864. Source: FlyBase

sensory organ development

Inferred from mutant phenotype PubMed 11884035. Source: FlyBase

spermatid development

Inferred from mutant phenotype PubMed 21652648. Source: FlyBase

   Cellular_componentcytoplasm

Inferred from direct assay PubMed 22275148. Source: FlyBase

microvillus

Inferred from mutant phenotype PubMed 14744998. Source: FlyBase

nucleus

Inferred from direct assay PubMed 22275148. Source: FlyBase

rhabdomere

Inferred from mutant phenotype PubMed 14744998. Source: FlyBase

   Molecular_functionactin binding

Inferred from sequence or structural similarity PubMed 10908588. Source: FlyBase

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

nwkQ9VSU83EBI-132019,EBI-167691

Sequences

Sequence LengthMass (Da)Tools
Q9VAT0 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 1E02454B47445C2E

FASTA52756,974
        10         20         30         40         50         60 
MSSGMRSQDG PRAKVNAAST LLTQEENEAV FKLLGKKCQT LNTAVVQIYK TEGSAHAHWK 

        70         80         90        100        110        120 
KRHTGVVCFV KDSAIRSYFM RAYCLIKNEL IWEHEIYDGM EVVKSRPFLL TFEGSDGHVG 

       130        140        150        160        170        180 
LNFVSEEECD SFFRIVDATI ETRNRKRQEK RNRQKSQQAP NAPLPQVQRE PARPPPMQGG 

       190        200        210        220        230        240 
LSSTDGVQLR NNKINSVTLT PAPAPAQSKN FLSSSFGLGN NAKDKKRKVT KADISRPTNF 

       250        260        270        280        290        300 
VHLSHVGWDA QKGFDLAGNE NDEVLNEFFV KAGVSEVELK DRDTRAFIYD FIQSNNVLAS 

       310        320        330        340        350        360 
VKQYSVESPT ETAAPMPPPV PTRHPSNGNQ RTAPPLPPAR QPPPAVPVTV PGAARAPPPP 

       370        380        390        400        410        420 
NRPPPISTAP PPPPVSAPVV APPPPPPPPP AAVPPPPPPP MPVGEIPVIT TTHAPTQAAR 

       430        440        450        460        470        480 
PAAPAAPDPR NALMDAIRKG TQLKKVDTTA LSTGSGDSRS DLMKDIRQGT VLKPAKEREL 

       490        500        510        520 
GSQRNSDSGA GTDALADALR RALAARGNAI HSDEDETESS DNEGEWD 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. expand/collapse author list , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.
Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley EMBL AAL48047.1.
[3]"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence."
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. expand/collapse author list , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[4]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[5]"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[6]"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[7]"Combined evidence annotation of transposable elements in genome sequences."
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[8]"Drosophila melanogaster release 4 sequence."
Berkeley Drosophila Genome Project
Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[9]Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[10]"The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
Smith C.D., Shu S., Mungall C.J., Karpen G.H.
Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[11]"Sequence finishing and mapping of Drosophila melanogaster heterochromatin."
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E.
Science 316:1625-1628(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[12]FlyBase
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014297 Genomic DNA. Translation: AAF56819.1.
AY070576 mRNA. Translation: AAL48047.1.
AE014297 Genomic DNA. Translation: AAN14303.1.
RefSeqNP_001263045.1. NM_001276116.1.
NP_651637.1. NM_143380.4.
NP_733257.1. NM_170378.2.
UniGeneDm.6373.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-742333.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0085352; FBpp0084721; FBgn0024273.
FBtr0085353; FBpp0084722; FBgn0024273.
GeneID43402.
KEGGdme:Dmel_CG1520.
UCSCCG1520-RA. d. melanogaster.

Organism-specific databases

CTD43402.
FlyBaseFBgn0024273. WASp.

Phylogenomic databases

GeneTreeENSGT00730000110895.
InParanoidQ9VAT0.
KOK05747.
OMALIWEHEI.

Family and domain databases

Gene3D2.30.29.30. 1 hit.
3.90.810.10. 1 hit.
InterProIPR000095. CRIB_dom.
IPR011993. PH_like_dom.
IPR027641. WASP.
IPR011026. WASP_C.
IPR000697. WH1/EVH1.
IPR003124. WH2_dom.
[Graphical view]
PANTHERPTHR12779. PTHR12779. 1 hit.
PfamPF00786. PBD. 1 hit.
PF00568. WH1. 1 hit.
PF02205. WH2. 2 hits.
[Graphical view]
SMARTSM00246. WH2. 2 hits.
[Graphical view]
SUPFAMSSF47912. SSF47912. 2 hits.
PROSITEPS50108. CRIB. 1 hit.
PS50229. WH1. 1 hit.
PS51082. WH2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSWAS. drosophila.
GenomeRNAi43402.
NextBio833747.
PROQ9VAT0.

Entry information

Entry nameQ9VAT0_DROME
AccessionPrimary (citable) accession number: Q9VAT0
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)