Q9VA36 (Q9VA36_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG31012, isoform C EMBL AAF57087.2

Gene names

Name:	cindr FlyBase FBgn0027598
ORF Names:	CG31012 FlyBase FBgn0027598, Dmel_CG31012 EMBL AAF57087.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	882 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 3 SH3 domains. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	actin filament organization Inferred from mutant phenotype. Source: FlyBase border follicle cell migration Inferred from mutant phenotype. Source: FlyBase compound eye morphogenesis Inferred from mutant phenotype. Source: FlyBase cytokinesis Inferred from mutant phenotype. Source: FlyBase intercellular bridge organization Inferred from mutant phenotype. Source: FlyBase positive regulation of receptor-mediated endocytosis Inferred from genetic interaction. Source: FlyBase
Cellular component	cleavage furrow Inferred from direct assay. Source: FlyBase intercellular bridge Inferred from direct assay. Source: FlyBase midbody Inferred from direct assay. Source: FlyBase
Molecular function	SH3 domain binding Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VA36 [UniParc]. Last modified June 1, 2003. Version 2. Checksum: 59EF169E85EFDD4A	FASTA	882	92,423
	10 20 30 40 50 60 MENNICAIVE YEYAAKEPDE LDLQKGAIIH RIKQMPGGWW QGTLKASGVT GMFPDNFVRV 70 80 90 100 110 120 LESGVSSNGN GTTGSGDHIE VGTAVQLRDK SATSNRRCKV IYSYTQVNDD ELTLAVGDVI 130 140 150 160 170 180 EFLGEVEEGW WRGRLRSKVG VFPSNFVQHI EPSPVLASKR PPTIGATVTT SALTSKAANV 190 200 210 220 230 240 ANVAATATVP TGGAVPPAST SISTSTTKQA TKSRATAAAA ASAPAEPAAI VSGSGAAAGG 250 260 270 280 290 300 GAAAAVPMLP PKPQREFCRV EFPYAPQNDD ELELKVDDII AVISTELPDK GWWKGEIRGK 310 320 330 340 350 360 VGVFPDNFVK MLAPSEVAPI NEPPSATQIT QNQRKVSNTA STTSHMTTTN SSNSSTTSVT 370 380 390 400 410 420 TQQQKEQIGG SSSTTSKVYI KKTGSSSNST TSSTTTASSS AGRKESFGSR DSLNDILSET 430 440 450 460 470 480 GLPTGNVAAQ RKSLENKNLD LTKPPGVGAS VSIGQQRSST SSATTSSATT VATGLTSSSV 490 500 510 520 530 540 SKSMENMLDE KVKSPPPPVL SKKPSVPLKK TPTGGVPMTG NLLGGKKKNT EGKLTTAVSH 550 560 570 580 590 600 DLADGLAASK MLSGANQLPE SGAAGNVVIR RAATIAVEDT DFDRVERASI LTDMRQGRVK 610 620 630 640 650 660 APKRRPPSAA INVLGESNNN SVYVNGSGMS GSGGAGSASE LSEDGGAGGK TSDDNSTGEE 670 680 690 700 710 720 PQLAKPKPRE WEKKKAPWME ELKASQVTRK KTSPSVEPRG ASVAERTSKL FAAEQAVSSN 730 740 750 760 770 780 SSSITTKVQS SAVTSSMFVE NSTTSSSVIT SSSHTTTNDA IMSRSLSAAK VQTASSDEET 790 800 810 820 830 840 RATRPNSLAI RNQRSVSPLV KSSNASSSQS QEEKPTSQLN NHQDASSSRV AQLEQRVDKL 850 860 870 880 EGLVLNQQRT IEELVNALKS EAERVKILRS ELDKYAQCVT QV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF57087.2.
RefSeq	NP_733405.2. NM_170526.2.
UniGene	Dm.3169.
3D structure databases
HSSP	HSSP built from PDB template 1GCQ based on UniProtKB P27870.
ProteinModelPortal	Q9VA36.
SMR	Q9VA36. Positions 5-154, 254-315.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-21242N.
IntAct	Q9VA36. 4 interactions.
MINT	MINT-1559255.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0085704; FBpp0085066; FBgn0027598.
GeneID	43654.
KEGG	dme:Dmel_CG31012.
UCSC	CG31012-RC. d. melanogaster.
Organism-specific databases
CTD	43654.
FlyBase	FBgn0027598. cindr.
Phylogenomic databases
InParanoid	Q9VA36.
OMA	RRCKVIY.
PhylomeDB	Q9VA36.
Gene expression databases
ArrayExpress	Q9VA36.
Bgee	Q9VA36.
Family and domain databases
InterPro	IPR000108. p67phox. IPR011511. SH3_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00018. SH3_1. 2 hits. PF07653. SH3_2. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX.
SMART	SM00326. SH3. 3 hits. [Graphical view]
SUPFAM	SSF50044. SH3. 3 hits.
PROSITE	PS50002. SH3. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	835084.

Entry information

Entry name

Q9VA36_DROME

Accession

Primary (citable) accession number: Q9VA36

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 92 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)