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Protein

Probable rRNA-processing protein EBP2 homolog

Gene

CG1542

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the processing of the 27S pre-rRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis

Enzyme and pathway databases

ReactomeiR-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable rRNA-processing protein EBP2 homolog
Gene namesi
ORF Names:CG1542
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039828. CG1542.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001199971 – 307Probable rRNA-processing protein EBP2 homologAdd BLAST307

Proteomic databases

PaxDbiQ9V9Z9.
PRIDEiQ9V9Z9.

Expressioni

Gene expression databases

BgeeiFBgn0039828.
GenevisibleiQ9V9Z9. DM.

Interactioni

Protein-protein interaction databases

BioGridi68536. 2 interactors.
DIPiDIP-22231N.
IntActiQ9V9Z9. 5 interactors.
MINTiMINT-981279.
STRINGi7227.FBpp0085119.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili205 – 252Sequence analysisAdd BLAST48

Sequence similaritiesi

Belongs to the EBP2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3080. Eukaryota.
ENOG410YYHN. LUCA.
GeneTreeiENSGT00390000014984.
InParanoidiQ9V9Z9.
KOiK14823.
OMAiMFHRQAQ.
OrthoDBiEOG091G0HC5.
PhylomeDBiQ9V9Z9.

Family and domain databases

InterProiView protein in InterPro
IPR008610. Ebp2.
PANTHERiPTHR13028. PTHR13028. 1 hit.
PfamiView protein in Pfam
PF05890. Ebp2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9V9Z9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDFEMEDSA SGYDSGDNSD AELQAAFERG DLKPGLNVEF NGQRDKVNDV
60 70 80 90 100
TKLLAKTEAI KMQLPWLERL DMINTLAPLA PELAVQLEKH EQKRANLFKG
110 120 130 140 150
NAKLPYIRPE EDPVLNDFKR EMLFHRQAQS AVLEAIPRLH ELGIKTRRPD
160 170 180 190 200
DYFAEMAKSD EHMQKVRANL MAKQQGQAKS ERIKQIREQR KMGKMLAKQT
210 220 230 240 250
KVQREAEKKD MLDKLKKFRK GKLKNLDFLE DAKALESKQK QSAENRKKRN
260 270 280 290 300
KKFGFGGKKK GLKRNTKSSS AGLDGDKSSR RQRGVKAGAS VNKRLGKSRR

IKAKGRK
Length:307
Mass (Da):35,077
Last modified:May 1, 2000 - v1
Checksum:i8FFA4907E621F45E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF57129.1.
AY051756 mRNA. Translation: AAK93180.1.
RefSeqiNP_651850.1. NM_143593.4.
UniGeneiDm.1383.

Genome annotation databases

EnsemblMetazoaiFBtr0085757; FBpp0085119; FBgn0039828.
GeneIDi43691.
KEGGidme:Dmel_CG1542.
UCSCiCG1542-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF57129.1.
AY051756 mRNA. Translation: AAK93180.1.
RefSeqiNP_651850.1. NM_143593.4.
UniGeneiDm.1383.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi68536. 2 interactors.
DIPiDIP-22231N.
IntActiQ9V9Z9. 5 interactors.
MINTiMINT-981279.
STRINGi7227.FBpp0085119.

Proteomic databases

PaxDbiQ9V9Z9.
PRIDEiQ9V9Z9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0085757; FBpp0085119; FBgn0039828.
GeneIDi43691.
KEGGidme:Dmel_CG1542.
UCSCiCG1542-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0039828. CG1542.

Phylogenomic databases

eggNOGiKOG3080. Eukaryota.
ENOG410YYHN. LUCA.
GeneTreeiENSGT00390000014984.
InParanoidiQ9V9Z9.
KOiK14823.
OMAiMFHRQAQ.
OrthoDBiEOG091G0HC5.
PhylomeDBiQ9V9Z9.

Enzyme and pathway databases

ReactomeiR-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Miscellaneous databases

ChiTaRSiCG1542. fly.
GenomeRNAii43691.
PROiPR:Q9V9Z9.

Gene expression databases

BgeeiFBgn0039828.
GenevisibleiQ9V9Z9. DM.

Family and domain databases

InterProiView protein in InterPro
IPR008610. Ebp2.
PANTHERiPTHR13028. PTHR13028. 1 hit.
PfamiView protein in Pfam
PF05890. Ebp2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEBP2_DROME
AccessioniPrimary (citable) accession number: Q9V9Z9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: May 1, 2000
Last modified: June 7, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.