Q9V9T4 (Q9V9T4_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP-dependent chromatin assembly factor large subunit EMBL AAF57200.1
EC=2.3.1.48 EMBL AAF57200.1

Gene names

Name:	Acf1 EMBL AAF57200.1
ORF Names:	Dmel_CG1966 EMBL AAF57200.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1476 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Acyltransferase EMBL AAF57200.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dendrite morphogenesis Inferred from mutant phenotype. Source: FlyBase epidermis development Inferred from mutant phenotype. Source: FlyBase muscle organ development Inferred from mutant phenotype. Source: FlyBase negative regulation of transcription, DNA-dependent Inferred from mutant phenotype. Source: FlyBase nucleosome assembly Inferred from direct assay. Source: FlyBase nucleosome mobilization Inferred from direct assay. Source: FlyBase nucleosome positioning Inferred from direct assay. Source: FlyBase regulation of ATPase activity Inferred from direct assay. Source: FlyBase
Cellular component	ACF complex Inferred from direct assay. Source: FlyBase chromatin accessibility complex Inferred from direct assay. Source: FlyBase
Molecular function	DNA binding Inferred from direct assay. Source: FlyBase histone acetyltransferase activity Inferred from electronic annotation. Source: EC protein binding Inferred from physical interaction. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9V9T4 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 9EE1906672E5B006	FASTA	1,476	170,412
	10 20 30 40 50 60 MPICKREGFD LNQKEGKNET FHDNDQVFCC YITKRIFRDY EHYFRHVMVI NSTVWQCEAT 70 80 90 100 110 120 GKENLTYEEA VKSERAARKK MEQFKQSLRA PVLLVVEHAQ QSAVNTLNMI VAKFLRKRYF 130 140 150 160 170 180 IGEEVSVQAK KNATYTVLGV KLDKNMPEPL NGIYEDTDNL VYRLRPNKGD PSAELDLPFR 190 200 210 220 230 240 QLRRSRMEFN LENLSMFIKS NVSRVDGLLR PKPEAYKQYV TDPGVNFSTI FIGKMPRYSP 250 260 270 280 290 300 AKIKKPDGKK QSTLNKYIVA GEATAAKSKA KAKSDAKSLA EELERVKREK EAKLIELEKQ 310 320 330 340 350 360 KAEKKAQLIE RVENECNLLL QKTDDLERTD QKVLPRYRQI VTLLPEHLLG DAFMMREFMH 370 380 390 400 410 420 TYTGLLSGIE VFRQNLSFYE MTRALTAREI AGPLSDILLV LLGTVFDLQK EEEEECAVTY 430 440 450 460 470 480 LDRAAQTQEP YWSMAQAAKS HLYAKRHFSF KVNELPLDAL TLSEVLRLHL LGSGAFVNEK 490 500 510 520 530 540 AERWRVMYRN GYSSKEDPGL ELRLEHSHIL RILKNHSVYQ LKFKDIMLLI RCLMSQIMTY 550 560 570 580 590 600 SGTINLIEER MEQTAKARQD LRALVVGENK RLAAVEINRK KLTQMHHLEV NGVEPEKREA 610 620 630 640 650 660 LVEKLKKSIA ELHAQSDQQH RKHELQMLKL HSQLFNFLVY LGMDRCYRKY YVLESMPGIF 670 680 690 700 710 720 VEHSPDSLDT CLEQPITNKS QIEIRQQSAL PKNRKDLRVY LLKLYGDDEK KTKKKAKHSL 730 740 750 760 770 780 ENKENQEHRL NGSAEPMDVE SDSPEAPTHF ELLMCSGDKR SCIVHDSRNG QRQRWAYIYK 790 800 810 820 830 840 AEEIDELIKA LNPNGLREYE LLQELSVLRS LIEQHAKTCP VDLLSLENET MRKKFMAAME 850 860 870 880 890 900 SETNRKYGEA NFGLPNGTDL NEVMRLHLVD RIIQFENDIY TGDLGRLKVK DMEKWRSDLL 910 920 930 940 950 960 GGNYDAQCKL QWGPGGKLED EAGSDNESHE THEEDDGALL GKYARKPYRD PGMYLAASAD 970 980 990 1000 1010 1020 TKPLPDSDDE EDQHTNAVSI PIAVHNMASA LLQVEQAIGK RFLKEPYGMK KWDPKQEALK 1030 1040 1050 1060 1070 1080 LACDSRLHQW EVSLMESTSF AQVFLHLNIL HDCIQWRRST NKSLCKVCRR GSDPEKMLLC 1090 1100 1110 1120 1130 1140 DECNAGTHMF CLKPKLRSVP PGNWYCNDCV KSLGLSNGQN EKDKKQATKK KRKFIVEEED 1150 1160 1170 1180 1190 1200 DEATDEEEEE KKDDDMTDED AEHENEKHDE DVEDDESVTS TPSSSRVNGR ILRRPRTRPT 1210 1220 1230 1240 1250 1260 SRRLTSKEIE EHAQEDVDSG DVSDDASLTA GEDTIEDESD EEKVCQKCFY DGGEIKCVQC 1270 1280 1290 1300 1310 1320 RLFFHLECVH LKRPPRTDFV CKTCKPMPQR PRRRHSNMNG DHDRDEEEPK AKRPRNSLRL 1330 1340 1350 1360 1370 1380 SIDKTARPSN GNNNNNNNNS SVNNNNHRRS GRRTNEHMPL NSAALYDLLE QIMKHKAAWP 1390 1400 1410 1420 1430 1440 FLRPVLTSEV PDYHQIIKTP MDLAKIKSKL NMGAYQLNEE LLSDIQLVFR NCDLYNVEGN 1450 1460 1470 EIYDAGCQLE RFVIDRCRDM QLPFRPSDMN GEVKAC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF57200.1.
RefSeq	NP_536734.2. NM_080486.2.
UniGene	Dm.3122.
3D structure databases
HSSP	HSSP built from PDB template 1F62 based on UniProtKB Q9UIG0.
ProteinModelPortal	Q9V9T4.
SMR	Q9V9T4. Positions 1063-1112, 1362-1460.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9V9T4. 1 interaction.
MINT	MINT-1328832.
STRING	Q9V9T4.
Proteomic databases
PRIDE	Q9V9T4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0085845; FBpp0085204; FBgn0027620.
GeneID	43751.
KEGG	dme:Dmel_CG1966.
NMPDR	fig|7227.3.peg.15656.
UCSC	CG1966-RA. d. melanogaster.
Organism-specific databases
CTD	110112.
FlyBase	FBgn0027620. Acf1.
Phylogenomic databases
InParanoid	Q9V9T4.
OMA	CKVCRRG.
PhylomeDB	Q9V9T4.
Gene expression databases
ArrayExpress	Q9V9T4.
Bgee	Q9V9T4.
Family and domain databases
InterPro	IPR001487. Bromodomain. IPR018500. DDT_dom_subgr. IPR018501. DDT_dom_superfamily. IPR013136. WSTF_Acf1_Cbp146. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Gene3D	G3DSA:1.20.920.10. Bromodomain. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 2 hits.
KO	K11655.
Pfam	PF00439. Bromodomain. 1 hit. PF00628. PHD. 1 hit. PF10537. WAC_Acf1_DNA_bd. 1 hit. [Graphical view]
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00297. BROMO. 1 hit. SM00571. DDT. 1 hit. SM00249. PHD. 2 hits. [Graphical view]
SUPFAM	SSF47370. Bromodomain. 1 hit. SSF57903. FYVE_PHD_ZnF. 2 hits.
PROSITE	PS50014. BROMODOMAIN_2. 1 hit. PS50827. DDT. 1 hit. PS51136. WAC. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	835602.

Entry information

Entry name

Q9V9T4_DROME

Accession

Primary (citable) accession number: Q9V9T4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)