Q9V9S7 (SYDE_DROME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Rho GTPase-activating protein 100F
Short name=RhoGAP-100F

Alternative name(s):
Synapse defective protein 1 homolog
Short name=Protein syd-1 homolog

Gene names

Name:	RhoGAP100F
ORF Names:	CG1976

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1866 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state By similarity.
Sequence similarities	Contains 1 C2 domain. Contains 1 PDZ (DHR) domain. Contains 1 Rho-GAP domain.
Sequence caution	The sequence AAM11366.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Molecular function	GTPase activation
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	activation of Rho GTPase activity Inferred from sequence or structural similarity. Source: UniProtKB signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	Rho GTPase activator activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform D (identifier: Q9V9S7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform C (identifier: Q9V9S7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-27: MQWKKKFTRLKAATGNSRVRRMLCCGR → MCDSATTGCFLTRSSH

Note: No experimental confirmation available.

Isoform B (identifier: Q9V9S7-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1185-1191: RRGESTG → NVLPASD
     1192-1866: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1866	1866	Rho GTPase-activating protein 100F		PRO_0000312161
Regions
	Domain	179 – 264	86	PDZ
	Domain	804 – 887	84	C2
	Domain	948 – 1148	201	Rho-GAP
	Compositional bias	350 – 354	5	Poly-Gly
	Compositional bias	366 – 370	5	Poly-Pro
	Compositional bias	538 – 541	4	Poly-Tyr
	Compositional bias	1399 – 1788	390	Ser-rich
Amino acid modifications
	Modified residue	719	1	Phosphoserine Ref.4
Natural variations
	Alternative sequence	1 – 27	27	MQWKK…LCCGR → MCDSATTGCFLTRSSH in isoform C.		VSP_041784
	Alternative sequence	1185 – 1191	7	RRGESTG → NVLPASD in isoform B.		VSP_041785
	Alternative sequence	1192 – 1866	675	Missing in isoform B.		VSP_041786

Sequences

	Sequence		Length	Mass (Da)
	Isoform D [UniParc]. Last modified September 21, 2011. Version 2. Checksum: A156B00E25BE412A	FASTA	1,866	198,298
	10 20 30 40 50 60 MQWKKKFTRL KAATGNSRVR RMLCCGRRKE NGRSVPDVTA SPGRAPPGPL PANQMPAMGN 70 80 90 100 110 120 QQHHGNQQHH GNQQQHHGNQ HSNHRGQSGS LSNAAGVKDP VMLQGDFRKV SGISSEIFRQ 130 140 150 160 170 180 IEAVENDHDP NTAAALEAVE RRGEMIVRVL EPRCMGSKQA VDAAHKLMNK ADARHTVQLV 190 200 210 220 230 240 EIVKRPGQTL GLYIREGNGA DRTDGVFISR IALESAVYNS GCLRVGDEIL AVNLVDVTHM 250 260 270 280 290 300 SLDDVVIIMS IPRRLVLAIR QRRGNRGTGS PGPPTLSRPE QKPPPVVVIK RDLRDEDLDE 310 320 330 340 350 360 TDRMPRPRSS RDRRTGDGRE MTESRSRLGL GLNNYSPQSE QLDMYYNTRG GGGGAMGEPP 370 380 390 400 410 420 NWGYKPPPPP SSVITEQPTK AHAFAPSHAY YQNAGTLESL AEKVHAFYPG QPGGPPVGPS 430 440 450 460 470 480 RRMSTGTGNV GLAQQHARFP RSGSDQHLPR VEYSDYSNSL GRHSLLRSSL KPGTTGGAPM 490 500 510 520 530 540 QVGVGGTLGR YGRYDQQRAG VSKYGPPSGG AQSLTRRSRP NLDYSSDTEA TIGPRPSYYY 550 560 570 580 590 600 YNRPAIGSMS RGSGGAGGGV GAASTAALLA GAADLNKFNS LPRERPGTRL QGIRSRMGDR 610 620 630 640 650 660 LVDENDGNTS APEFDVRRGR DLRQRITASP SIFTADEYRA WLRRAPSSSA IAEQMRMTRD 670 680 690 700 710 720 MFAQPRAQRF SCSAENIHDA LRNTESIYSS RNHILGTGTL DRNMGLTRPI SALPVRSMSS 730 740 750 760 770 780 QHIGGAGSIR SPSIRRMRQL LELSAGPASP SGSILSTGGH QSPAPTPSAT LPRPHRQIDI 790 800 810 820 830 840 NPAEFAKYKL DKPIVDIGGI SGMLWIHLLA GRGLRTAPEG AAGTATQGQT RDLYCVIECD 850 860 870 880 890 900 RVHKARTVVR SGDLQFDWDE SFELDLVGNK QLDVLVYSWD PQHRHKLCYR GAISLSSILR 910 920 930 940 950 960 QSPLHQLALK VEPRGTIYIR MRHTDPLALY KRRGLPSLRA GYPTLFGADL ETVVNRESKN 970 980 990 1000 1010 1020 APGSAPVPIV LRRCVEEVER RGLDIIGLYR LCGSATKKRL LREAFERNSR AVELTPEHVP 1030 1040 1050 1060 1070 1080 DINVITGVLK DYLRELPEPL FTRCLFQMTV DALAVCLPDD PEGNAKLMLS ILDCLPRANR 1090 1100 1110 1120 1130 1140 ATLVFLLDHL SLVVSNSERN KMSAQALATV MGPPLMLHSA SAQPGADIDH AQPIAVLKYL 1150 1160 1170 1180 1190 1200 LQIWPQPQAQ HQQMAQHMGG AAGAMMGGLV TAGSMSNMAG VASGRRGEST GQRGSKVSAL 1210 1220 1230 1240 1250 1260 PADRQQLLLQ QQAQLMAAGN LLRSSTSVTN ILSQGHPQLS ATANNHLYQS VVGQLAQSHR 1270 1280 1290 1300 1310 1320 ALQQAVQQPY QLGGSVGSAI PDPSPLPLPG TPSPGSSSAS TGSGSGSGKS TDTIKRGASP 1330 1340 1350 1360 1370 1380 VSVKQVKIVD QPSSPYSIVM KKPPLQKDAP VEITTPTTQA DTESTLGCKE SNGTASRRGN 1390 1400 1410 1420 1430 1440 VDFYDTHKTQ AKSVVNEESS YSSKYTGSET KKIIPGNSSY TPSKANASGL SGGEDYKAMR 1450 1460 1470 1480 1490 1500 NKSSATSSSS SSQATVLSAG STATSAPTTS SDDSDDLVSY KSSASTNALL AQSQAMTTSQ 1510 1520 1530 1540 1550 1560 LMSKYLKREP RVQFTPIKSP ESPSPPGSGD GLPKGTYQLV TPISGSSSKP GATTGAISKY 1570 1580 1590 1600 1610 1620 TTGSVESSIN ANSQKLSSPS RLCNSKDSNS RTGTASSTTP ATSMVSTGRR LFDSLASSSS 1630 1640 1650 1660 1670 1680 SETETKTYIG GTTAASGAIT TTIYTNDTKN SGSSSSKSGI GGGSGTGLGA VSGASSETRS 1690 1700 1710 1720 1730 1740 FGSTLFGSSG LGNGNGSSHN HSSASPSPFT TTNGNGNHNT MHLYGTLPKN GTSTGAALFG 1750 1760 1770 1780 1790 1800 GSANSSSYHS SASGSGAGTA SSSGVSSMTG STNSYDFYTS TSSTVSSSRP FANGGNNYHT 1810 1820 1830 1840 1850 1860 LGTYRAQYAA TNPFLDAFDE KPGSNGGNAH GEEKLGADKG HHRAAVMAFQ SSGDSKNGSD EYDDIK
	Isoform C [UniParc]. Checksum: 5BD3843FEF014B79	FASTA	1,855	196,788
	10 20 30 40 50 60 MCDSATTGCF LTRSSHRKEN GRSVPDVTAS PGRAPPGPLP ANQMPAMGNQ QHHGNQQHHG 70 80 90 100 110 120 NQQQHHGNQH SNHRGQSGSL SNAAGVKDPV MLQGDFRKVS GISSEIFRQI EAVENDHDPN 130 140 150 160 170 180 TAAALEAVER RGEMIVRVLE PRCMGSKQAV DAAHKLMNKA DARHTVQLVE IVKRPGQTLG 190 200 210 220 230 240 LYIREGNGAD RTDGVFISRI ALESAVYNSG CLRVGDEILA VNLVDVTHMS LDDVVIIMSI 250 260 270 280 290 300 PRRLVLAIRQ RRGNRGTGSP GPPTLSRPEQ KPPPVVVIKR DLRDEDLDET DRMPRPRSSR 310 320 330 340 350 360 DRRTGDGREM TESRSRLGLG LNNYSPQSEQ LDMYYNTRGG GGGAMGEPPN WGYKPPPPPS 370 380 390 400 410 420 SVITEQPTKA HAFAPSHAYY QNAGTLESLA EKVHAFYPGQ PGGPPVGPSR RMSTGTGNVG 430 440 450 460 470 480 LAQQHARFPR SGSDQHLPRV EYSDYSNSLG RHSLLRSSLK PGTTGGAPMQ VGVGGTLGRY 490 500 510 520 530 540 GRYDQQRAGV SKYGPPSGGA QSLTRRSRPN LDYSSDTEAT IGPRPSYYYY NRPAIGSMSR 550 560 570 580 590 600 GSGGAGGGVG AASTAALLAG AADLNKFNSL PRERPGTRLQ GIRSRMGDRL VDENDGNTSA 610 620 630 640 650 660 PEFDVRRGRD LRQRITASPS IFTADEYRAW LRRAPSSSAI AEQMRMTRDM FAQPRAQRFS 670 680 690 700 710 720 CSAENIHDAL RNTESIYSSR NHILGTGTLD RNMGLTRPIS ALPVRSMSSQ HIGGAGSIRS 730 740 750 760 770 780 PSIRRMRQLL ELSAGPASPS GSILSTGGHQ SPAPTPSATL PRPHRQIDIN PAEFAKYKLD 790 800 810 820 830 840 KPIVDIGGIS GMLWIHLLAG RGLRTAPEGA AGTATQGQTR DLYCVIECDR VHKARTVVRS 850 860 870 880 890 900 GDLQFDWDES FELDLVGNKQ LDVLVYSWDP QHRHKLCYRG AISLSSILRQ SPLHQLALKV 910 920 930 940 950 960 EPRGTIYIRM RHTDPLALYK RRGLPSLRAG YPTLFGADLE TVVNRESKNA PGSAPVPIVL 970 980 990 1000 1010 1020 RRCVEEVERR GLDIIGLYRL CGSATKKRLL REAFERNSRA VELTPEHVPD INVITGVLKD 1030 1040 1050 1060 1070 1080 YLRELPEPLF TRCLFQMTVD ALAVCLPDDP EGNAKLMLSI LDCLPRANRA TLVFLLDHLS 1090 1100 1110 1120 1130 1140 LVVSNSERNK MSAQALATVM GPPLMLHSAS AQPGADIDHA QPIAVLKYLL QIWPQPQAQH 1150 1160 1170 1180 1190 1200 QQMAQHMGGA AGAMMGGLVT AGSMSNMAGV ASGRRGESTG QRGSKVSALP ADRQQLLLQQ 1210 1220 1230 1240 1250 1260 QAQLMAAGNL LRSSTSVTNI LSQGHPQLSA TANNHLYQSV VGQLAQSHRA LQQAVQQPYQ 1270 1280 1290 1300 1310 1320 LGGSVGSAIP DPSPLPLPGT PSPGSSSAST GSGSGSGKST DTIKRGASPV SVKQVKIVDQ 1330 1340 1350 1360 1370 1380 PSSPYSIVMK KPPLQKDAPV EITTPTTQAD TESTLGCKES NGTASRRGNV DFYDTHKTQA 1390 1400 1410 1420 1430 1440 KSVVNEESSY SSKYTGSETK KIIPGNSSYT PSKANASGLS GGEDYKAMRN KSSATSSSSS 1450 1460 1470 1480 1490 1500 SQATVLSAGS TATSAPTTSS DDSDDLVSYK SSASTNALLA QSQAMTTSQL MSKYLKREPR 1510 1520 1530 1540 1550 1560 VQFTPIKSPE SPSPPGSGDG LPKGTYQLVT PISGSSSKPG ATTGAISKYT TGSVESSINA 1570 1580 1590 1600 1610 1620 NSQKLSSPSR LCNSKDSNSR TGTASSTTPA TSMVSTGRRL FDSLASSSSS ETETKTYIGG 1630 1640 1650 1660 1670 1680 TTAASGAITT TIYTNDTKNS GSSSSKSGIG GGSGTGLGAV SGASSETRSF GSTLFGSSGL 1690 1700 1710 1720 1730 1740 GNGNGSSHNH SSASPSPFTT TNGNGNHNTM HLYGTLPKNG TSTGAALFGG SANSSSYHSS 1750 1760 1770 1780 1790 1800 ASGSGAGTAS SSGVSSMTGS TNSYDFYTST SSTVSSSRPF ANGGNNYHTL GTYRAQYAAT 1810 1820 1830 1840 1850 NPFLDAFDEK PGSNGGNAHG EEKLGADKGH HRAAVMAFQS SGDSKNGSDE YDDIK
	Isoform B [UniParc]. Checksum: 654287653672CE07	FASTA	1,191	129,728
	10 20 30 40 50 60 MQWKKKFTRL KAATGNSRVR RMLCCGRRKE NGRSVPDVTA SPGRAPPGPL PANQMPAMGN 70 80 90 100 110 120 QQHHGNQQHH GNQQQHHGNQ HSNHRGQSGS LSNAAGVKDP VMLQGDFRKV SGISSEIFRQ 130 140 150 160 170 180 IEAVENDHDP NTAAALEAVE RRGEMIVRVL EPRCMGSKQA VDAAHKLMNK ADARHTVQLV 190 200 210 220 230 240 EIVKRPGQTL GLYIREGNGA DRTDGVFISR IALESAVYNS GCLRVGDEIL AVNLVDVTHM 250 260 270 280 290 300 SLDDVVIIMS IPRRLVLAIR QRRGNRGTGS PGPPTLSRPE QKPPPVVVIK RDLRDEDLDE 310 320 330 340 350 360 TDRMPRPRSS RDRRTGDGRE MTESRSRLGL GLNNYSPQSE QLDMYYNTRG GGGGAMGEPP 370 380 390 400 410 420 NWGYKPPPPP SSVITEQPTK AHAFAPSHAY YQNAGTLESL AEKVHAFYPG QPGGPPVGPS 430 440 450 460 470 480 RRMSTGTGNV GLAQQHARFP RSGSDQHLPR VEYSDYSNSL GRHSLLRSSL KPGTTGGAPM 490 500 510 520 530 540 QVGVGGTLGR YGRYDQQRAG VSKYGPPSGG AQSLTRRSRP NLDYSSDTEA TIGPRPSYYY 550 560 570 580 590 600 YNRPAIGSMS RGSGGAGGGV GAASTAALLA GAADLNKFNS LPRERPGTRL QGIRSRMGDR 610 620 630 640 650 660 LVDENDGNTS APEFDVRRGR DLRQRITASP SIFTADEYRA WLRRAPSSSA IAEQMRMTRD 670 680 690 700 710 720 MFAQPRAQRF SCSAENIHDA LRNTESIYSS RNHILGTGTL DRNMGLTRPI SALPVRSMSS 730 740 750 760 770 780 QHIGGAGSIR SPSIRRMRQL LELSAGPASP SGSILSTGGH QSPAPTPSAT LPRPHRQIDI 790 800 810 820 830 840 NPAEFAKYKL DKPIVDIGGI SGMLWIHLLA GRGLRTAPEG AAGTATQGQT RDLYCVIECD 850 860 870 880 890 900 RVHKARTVVR SGDLQFDWDE SFELDLVGNK QLDVLVYSWD PQHRHKLCYR GAISLSSILR 910 920 930 940 950 960 QSPLHQLALK VEPRGTIYIR MRHTDPLALY KRRGLPSLRA GYPTLFGADL ETVVNRESKN 970 980 990 1000 1010 1020 APGSAPVPIV LRRCVEEVER RGLDIIGLYR LCGSATKKRL LREAFERNSR AVELTPEHVP 1030 1040 1050 1060 1070 1080 DINVITGVLK DYLRELPEPL FTRCLFQMTV DALAVCLPDD PEGNAKLMLS ILDCLPRANR 1090 1100 1110 1120 1130 1140 ATLVFLLDHL SLVVSNSERN KMSAQALATV MGPPLMLHSA SAQPGADIDH AQPIAVLKYL 1150 1160 1170 1180 1190 LQIWPQPQAQ HQQMAQHMGG AAGAMMGGLV TAGSMSNMAG VASGNVLPAS D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[3]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 938-1866 (ISOFORMS C/D). Strain: Berkeley. Tissue: Embryo.
[4]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-719, MASS SPECTROMETRY. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF57207.2. AE014297 Genomic DNA. Translation: ACZ95078.1. AE014297 Genomic DNA. Translation: ACZ95079.1. BT082117 mRNA. Translation: ACQ45355.1. AY095038 mRNA. Translation: AAM11366.1. Different initiation.
RefSeq	NP_001163785.1. NM_001170314.1. NP_001163786.1. NM_001170315.1. NP_651902.2. NM_143645.2.
UniGene	Dm.12850.
3D structure databases
HSSP	HSSP built from PDB template 1B8Q based on UniProtKB P29476.
ProteinModelPortal	Q9V9S7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9V9S7.
Proteomic databases
PRIDE	Q9V9S7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	43758.
KEGG	dme:Dmel_CG1976.
NMPDR	fig|7227.3.peg.15666.
UCSC	CG1976-RA. d. melanogaster.
Organism-specific databases
CTD	43758.
FlyBase	FBgn0039883. RhoGAP100F.
Phylogenomic databases
eggNOG	inNOG04730.
InParanoid	Q9V9S7.
OMA	SSQHIGG.
OrthoDB	EOG4DR7T8.
PhylomeDB	Q9V9S7.
Gene expression databases
ArrayExpress	Q9V9S7.
Bgee	Q9V9S7.
Family and domain databases
InterPro	IPR000008. C2_Ca-dep. IPR008973. C2_Ca/lipid-bd_dom_CaLB. IPR001478. PDZ/DHR/GLGF. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00595. PDZ. 1 hit. PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00239. C2. 1 hit. SM00228. PDZ. 1 hit. SM00324. RhoGAP. 1 hit. [Graphical view]
SUPFAM	SSF49562. C2_CaLB. 1 hit. SSF50156. PDZ. 1 hit. SSF48350. Rho_GAP. 1 hit.
PROSITE	PS50004. C2. False negative. PS50106. PDZ. 1 hit. PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	835643.

Entry information

Entry name

SYDE_DROME

Accession

Primary (citable) accession number: Q9V9S7
Secondary accession number(s): C3KGQ2 , E1JJ30, E1JJ31, Q8SWW5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	September 21, 2011
Last modified:	January 25, 2012
This is version 79 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project