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Protein
Submitted name:

BG1

Gene

Debcl

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • apoptotic process Source: FlyBase
  • apoptotic process involved in morphogenesis Source: FlyBase
  • cellular response to starvation Source: FlyBase
  • ectopic germ cell programmed cell death Source: FlyBase
  • extrinsic apoptotic signaling pathway in absence of ligand Source: GO_Central
  • intrinsic apoptotic signaling pathway in response to DNA damage Source: FlyBase
  • negative regulation of apoptotic process Source: FlyBase
  • negative regulation of neuron apoptotic process Source: FlyBase
  • neuron cellular homeostasis Source: FlyBase
  • positive regulation of macroautophagy Source: FlyBase
  • programmed cell death involved in cell development Source: FlyBase
  • regulation of mitochondrial membrane permeability Source: FlyBase
  • regulation of programmed cell death Source: FlyBase
  • response to ionizing radiation Source: FlyBase

Names & Taxonomyi

Protein namesi
Submitted name:
BG1Imported
Submitted name:
Bcl-2 ortholog dBorg-1Imported
Submitted name:
Death executioner Bcl-2 homologueImported
Submitted name:
Drob-1Imported
Submitted name:
IP01389pImported
Submitted name:
Proapoptotic Bcl-2 homolog DEBCLImported
Gene namesi
Name:DebclImported
Synonyms:dborg1Imported, debclImported, drob-1Imported
ORF Names:CG33134Imported, Dmel_CG33134Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0029131. Debcl.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei265 – 284HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial envelope Source: FlyBase
  • mitochondrial outer membrane Source: FlyBase
  • mitochondrion Source: FlyBase

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0029131.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-977316.
STRINGi7227.FBpp0085443.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
GeneTreeiENSGT00510000048498.
KOiK02561.
OMAiSNVCRRI.
OrthoDBiEOG091G0JPB.

Family and domain databases

InterProiView protein in InterPro
IPR002475. Bcl2-like.
IPR026298. Blc2_fam.
IPR026309. BOK.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF53. PTHR11256:SF53. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PRINTSiPR01862. BCL2FAMILY.
SUPFAMiSSF56854. SSF56854. 1 hit.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9V9C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPTTSPPPK LAKFKSSSLD HEIYTANRRG TIATASSDWK ALRGGVGGGA
60 70 80 90 100
GGPGSVPNPS NGRSLHAGGP MTRAASTSSL ASSTRTMTNY QEYKMDIINQ
110 120 130 140 150
GKCLCGQYIR ARLRRAGVLN RKVTQRLRNI LDPGSSHVVY EVFPALNSMG
160 170 180 190 200
EELERMHPRV YTNISRQLSR APFGELEDSD MAPMLLNLVA KDLFRSSITW
210 220 230 240 250
GKIISIFAVC GGFAIDCVRQ GHFDYLQCLI DGLAEIIEDD LVYWLIDNGG
260 270 280 290 300
WLGLSRHIRP RVGEFTFLGW LTLFVTISAG AYMVSNVCRR IGGQLYSLLF
Length:300
Mass (Da):32,940
Last modified:October 1, 2000 - v2
Checksum:iFF29E0ADCF3D0942
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF178430 mRNA. Translation: AAF26289.1.
AF222004 mRNA. Translation: AAF44324.1.
AF244352 mRNA. Translation: AAF44714.1.
AE013599 Genomic DNA. Translation: AAF57365.2.
BT022157 mRNA. Translation: AAY51552.1.
AB032430 mRNA. Translation: BAA89603.2.
RefSeqiNP_788278.1. NM_176098.3.
UniGeneiDm.1719.

Genome annotation databases

EnsemblMetazoaiFBtr0086108; FBpp0085443; FBgn0029131.
GeneIDi53585.
KEGGidme:Dmel_CG33134.
UCSCiCG33134-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9V9C8_DROME
AccessioniPrimary (citable) accession number: Q9V9C8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2000
Last modified: July 5, 2017
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported