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Protein
Submitted name:

Bip2

Gene

bip2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chromatin binding Source: FlyBase
  • metal ion binding Source: UniProtKB-KW
  • p53 binding Source: BHF-UCL
  • POZ domain binding Source: FlyBase
  • protein heterodimerization activity Source: InterPro
  • transcription factor binding Source: FlyBase

GO - Biological processi

  • positive regulation of transcription by RNA polymerase II Source: FlyBase

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-DME-674695 RNA Polymerase II Pre-transcription Events
R-DME-73776 RNA Polymerase II Promoter Escape
R-DME-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-DME-75953 RNA Polymerase II Transcription Initiation
R-DME-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance

Names & Taxonomyi

Protein namesi
Submitted name:
Bip2Imported
Gene namesi
Name:bip2Imported
Synonyms:bip-IIImported, BIP2Imported, Bip2Imported, dBIP2Imported, Dmel\CG2009Imported, DmTAF3Imported, dmTAF3Imported, dTAF[[II]]155Imported, dTAFII3Imported, i163Imported, i31Imported, TAF155Imported, TAF3Imported, TAF[[II]]155Imported, TAFII155Imported, TFIIDImported
ORF Names:CG2009Imported, Dmel_CG2009Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 4

Organism-specific databases

FlyBaseiFBgn0026262 bip2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ9V4D4
PRIDEiQ9V4D4

Expressioni

Gene expression databases

BgeeiFBgn0026262
ExpressionAtlasiQ9V4D4 differential
GenevisibleiQ9V4D4 DM

Interactioni

GO - Molecular functioni

  • p53 binding Source: BHF-UCL
  • POZ domain binding Source: FlyBase
  • protein heterodimerization activity Source: InterPro
  • transcription factor binding Source: FlyBase

Protein-protein interaction databases

IntActiQ9V4D4, 7 interactors
STRINGi7227.FBpp0088179

Structurei

3D structure databases

ProteinModelPortaliQ9V4D4
SMRiQ9V4D4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1340 – 1390PHD-typeInterPro annotationAdd BLAST51

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1973 Eukaryota
KOG2389 Eukaryota
ENOG41129NB LUCA
GeneTreeiENSGT00710000106806
InParanoidiQ9V4D4
KOiK14650
OMAiQMEHANR
OrthoDBiEOG091G00JZ
PhylomeDBiQ9V4D4

Family and domain databases

Gene3Di1.10.20.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR006565 BTP
IPR009072 Histone-fold
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF07524 Bromo_TP, 1 hit
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00576 BTP, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9V4D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMADRYASDL ALVVVAQITQ TIGYSCTLSA PLELLQDILQ KFVQEFARDM
60 70 80 90 100
HRHMEHANRI EPNLKDARLS IKNLSINVQE LLDYIGNVEP VGFIRDVPQF
110 120 130 140 150
PIGKSVNMNF LKPGSAETLT RPVYIFEYLP PMQDPELREI PADVQKEFSE
160 170 180 190 200
KQEFCSKAEY SSTNAADKLG AKHIDSISPN TVINFRSNAF ELDVGSSVRE
210 220 230 240 250
MSSVVMTTGG FISPAIEGKL PEDIIPDIVE KFLGLDAPFS PTIIVNSLQK
260 270 280 290 300
SPQLALSDRD KTVNPRKIIP SETKIFKQNA ALLTSGHSES SIIYASNNHT
310 320 330 340 350
MLTVTTPKKN RKQKHDLICE PGQSELLTNP FEKAQEKSQR KALKMYKQTS
360 370 380 390 400
KNQRDSSINQ IQNMKKLKKK FNRGSFDPNK KHLEKIFKKQ SKLKQNDLQL
410 420 430 440 450
DIDEKHFLQN SQTTSGLAIK ANSNENALQA DIPSQPPTVT SQIENNFRNS
460 470 480 490 500
IYPVQPSVIQ QTQVLLAEKK SGSEPERSKL DIFKKISKPR TPRPDIGATL
510 520 530 540 550
VPPGTGVSVF GSTMTPSALI SLPSGTTITP TPSLGLNSEN KNVPSMKINP
560 570 580 590 600
CNIFDGTIPL TKAGVEMSII DSPKPKKRGR KPGGKNVIKQ TNVVSQPLIN
610 620 630 640 650
KVERKKSSQA ITLPLSSSPM IITQSSLNVS PPTEPLNLCN TEQPSNNFLS
660 670 680 690 700
NLYAKEKKDR KKYKSLPENV MQLDKSCSPE KASTLHNSIR PTKQNNDVQC
710 720 730 740 750
SDKFVTISNA LSNASIYPGI QTGMVPLLPL LQFPPRPGLI PTGPGLFPAV
760 770 780 790 800
TGLVGFGNHG NRIPISPFID YPGPEESVAD TVRCPPIKDS PVTDSDQFLS
810 820 830 840 850
RSSTQTDLQM DRNYCNVAPL VPDSMKFAEC KSVSCASTIL ENPSAQATSK
860 870 880 890 900
INTKPLLEAS GNPDDPIEVS DDSDESMHNR QMVQRKTPIS SPTYVKTSFA
910 920 930 940 950
ELNPSSFTSA ASNGEEKSKM DLRNIVSLSS NEPLKKFKKL VKQSFPDVKS
960 970 980 990 1000
VPHTPASHSS FPQFNLPNFM GGDKFSLAGG ADLIPLSRVS DSEYSSKIVP
1010 1020 1030 1040 1050
FSSLGGTIPN QIKISEEHNI FSTFSNYEDI TITPTGLTSL EPKMRKHHKK
1060 1070 1080 1090 1100
LKKVKEGKNK KKKEKKDKSK KADQIGLPSF KSDRKIKAND KRQKKEKKKD
1110 1120 1130 1140 1150
KDKQILVHIP DDTEEFDKVP LANNDEPVLK SSSMTINPSL GAATSGISPN
1160 1170 1180 1190 1200
QIPKLTLKLS GKSTLFSSSE KEMTDAGKLK QTTILSSENK KRERDNSPEL
1210 1220 1230 1240 1250
ARFSPLVTGP PKNKQSETLH LGNSSTAVLP VPSPVAVRAV QLPVSQTSSN
1260 1270 1280 1290 1300
SAGWLSNPNN SNTASSTLSA SSVLLPQQLM LAPHTIMNNF VPAMCNSTGT
1310 1320 1330 1340 1350
VSKSGLCSSP PNTSEENANA MQIAESSRPS SYVDAEGNRI WICPACGKVD
1360 1370 1380 1390 1400
DGSAMIGCDG CDAWYHWICV GITFAPKDND DWFCRVCVTK KRIHGSEKKK

RRNKKK
Length:1,406
Mass (Da):154,501
Last modified:May 1, 2000 - v1
Checksum:iCF3EEC93FEA069BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014135 Genomic DNA Translation: AAF59342.1
RefSeqiNP_651923.2, NM_143666.3
UniGeneiDm.6500

Genome annotation databases

EnsemblMetazoaiFBtr0089110; FBpp0088179; FBgn0026262
GeneIDi43793
KEGGidme:Dmel_CG2009
UCSCiCG2009-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9V4D4_DROME
AccessioniPrimary (citable) accession number: Q9V4D4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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