Unreviewed, UniProtKB/TrEMBL Q9V472 (Q9V472_DROME)

Names and origin

Protein names

Submitted name:
    Lim1 EMBL AAF46413.2
Submitted name:
    DLim1 EMBL BAA86224.1
    GH04929p EMBL AAD55417.2

Gene names

Name:	Lim1 FlyBase FBgn0026411
Synonyms:	dlim1 EMBL BAA86224.1
ORF Names:	CG11354 FlyBase FBgn0026411, CG18616 FlyBase FBgn0028495 FlyBase FBgn0260444, Dmel_CG11354 EMBL AAF46413.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL BAA86224.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Nucleus By similarity. RuleBase RU000682V4
Sequence similarities	Contains 1 homeobox DNA-binding domain. Spearmint SPM001781 Contains 2 LIM zinc-binding domains. RuleBase RU000350V1 Spearmint SPM001781

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682V4 Spearmint SPM001781
Domain	Homeobox RuleBase RU000682V4 Spearmint SPM001781 LIM domain RuleBase RU000350V1 Spearmint SPM001781 Repeat Spearmint SPM001781
Ligand	DNA-binding RuleBase RU000682V4 Spearmint SPM001781 Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	imaginal disc-derived leg morphogenesis Inferred from mutant phenotype. Source: FlyBase leg disc proximal/distal pattern formation Inferred from mutant phenotype. Source: FlyBase regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9V472-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 0633EEBB873F7905	FASTA	505	54,788
	10 20 30 40 50 60 MAFGAVLHTS QHNIGRSEPP VGVGDPCAGC NKPILDKFLL NVLERAWHAS CVRCCECLQP 70 80 90 100 110 120 LTDKCFSRES KLYCRNDFFR RYGTKCSGCG QGIAPSDLVR KPRDKVFHLN CFTCCICRKQ 130 140 150 160 170 180 LSTGEQLYVL DDNKFICKDD YLLGKAPSCG HNSLSDSLMG SASEDDDDDD PPHLRATALG 190 200 210 220 230 240 LGVLGPNGPD SAGGPLGTSD ISVQSMSTDS KNTHDDSDQG SLDGDPDGRG DSQAENKSPD 250 260 270 280 290 300 DANGSKRRGP RTTIKAKQLE VLKTAFNQTP KPTRHIREQL AKETGLPMRV IQVWFQNKRS 310 320 330 340 350 360 KERRMKQITS MGRPPFFGGA RKMRGFPMNL SPGGLDDGPG FPYFAADAKF EFGYGGPFHP 370 380 390 400 410 420 HDGPYFPGHP GGPMPFNAPG GPMDHSGPIP MVNEFGLTPE ATFLGQAGGP PMQLQSAVGP 430 440 450 460 470 480 PPPPPPPSAE HLMAAAAAAA QQQAAQQQQQ QQQQQQQQQQ QNAQQAANQT QQQQQQNGPR 490 500 TNSPEFMSSA NFSEPQNMQN EGLVW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Drosophila melanogaster dlim1." Saigo K. Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAD55417.2.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[5]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF181631 mRNA. Translation: AAD55417.2. AE014298 Genomic DNA. Translation: AAF46413.2. AB034690 mRNA. Translation: BAA86224.1.
RefSeq	NP_572505.1.
UniGene	Dm.23547 Dm.3025
3D structure databases
HSSP	HSSP built from PDB template 1FJL based on UniProtKB P06601.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9V472. 24 interactions.
Proteomic databases
PRIDE	Q9V472.
Genome annotation databases
Ensembl	FBgn0026411. Drosophila melanogaster. [Contig view] FBgn0028495. Drosophila melanogaster. [Contig view]
GeneID	31813.
KEGG	dme:Dmel_CG11354.
NMPDR	fig|7227.3.peg.17043.
Organism-specific databases
FlyBase	FBgn0260444. CG18616. FBgn0026411. Lim1.
Phylogenomic databases
HOGENOM	Q9V472.
OMA	Q9V472. QTPKPTR.
Gene expression databases
ArrayExpress	Q9V472.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR012287. Homeodomain-rel. IPR001781. Znf_LIM. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. G3DSA:2.10.110.10. Znf_LIM. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF00412. LIM. 2 hits. [Graphical view]
ProDom	PD000010. Homeobox. 1 hit. PD000094. LIM. 2 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00389. HOX. 1 hit. SM00132. LIM. 2 hits. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	775444.

Entry information

Entry name

Q9V472_DROME

Accession

Primary (citable) accession number: Q9V472
Secondary accession number(s): Q9W3B9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)