Unreviewed, UniProtKB/TrEMBL Q9V428 (Q9V428_DROME)

Names and origin

Protein names

Submitted name:
    Icarus EMBL AAF53320.2
Submitted name:
    RE04081p EMBL ABY20526.1

Gene names

Name:	ics FlyBase FBgn0028546
Synonyms:	BG:BACR48E02.4 EMBL ABY20526.1
ORF Names:	Dmel_CG9031 EMBL AAF53320.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	Leucine-rich repeat Spearmint SPM003591 Repeat Spearmint SPM003591
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	apposition of dorsal and ventral imaginal disc-derived wing surfaces Inferred from mutant phenotype. Source: FlyBase negative regulation of JNK cascade Inferred from genetic interaction. Source: FlyBase negative regulation of JUN kinase activity Inferred from mutant phenotype. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9V428-1 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: B5DE7759056459EE	FASTA	283	31,850
	10 20 30 40 50 60 MSQSCIPVSA KMSKAKKVLD EARETHNPEL DLADKGLSSF EELPGLFNMS NITRLTLSHN 70 80 90 100 110 120 KISVISPGIA NLLNLEILNL SNNQLTELPV SLSSMPKLRI LNVSINRLIN LPRGFGAFPV 130 140 150 160 170 180 LEVLDLSYNN LNEQVLPGNF FGMETLRALY LGDNDFEYIP KEVGQLKNLQ ILGLRDNDLL 190 200 210 220 230 240 ELPREVGDLV RLRELHIQNN RLQVLPPEIA QLDLLSNKSV MKMEENPWVN PIAEQYLLGI 250 260 270 280 SHVIDYLKTE TYKIIYNRHL QAGRSGPPPP KADKSKKASR IRA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Carlson J., Frise E., Kapadia B., Park S., Wan K., Yu C., Celniker S. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL ABY20526.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF53320.2. BT031285 mRNA. Translation: ABY20526.1.
RefSeq	NP_609665.2.
UniGene	Dm.11259
3D structure databases
HSSP	HSSP built from PDB template 1M0Z based on UniProtKB P07359.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9V428. 9 interactions.
Genome annotation databases
Ensembl	FBgn0028546. Drosophila melanogaster. [Contig view]
GeneID	34774.
KEGG	dme:Dmel_CG9031.
NMPDR	fig|7227.3.peg.2299.
Organism-specific databases
FlyBase	FBgn0028546. ics.
Phylogenomic databases
HOGENOM	Q9V428.
OMA	Q9V428. DMCDRGI.
Gene expression databases
ArrayExpress	Q9V428.
Family and domain databases
InterPro	IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. [Graphical view]
Pfam	PF00560. LRR_1. 3 hits. [Graphical view]
SMART	SM00369. LRR_TYP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	790147.

Entry information

Entry name

Q9V428_DROME

Accession

Primary (citable) accession number: Q9V428

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 65 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)