Q9V419 (C28A5_DROME) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 90.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable cytochrome P450 28a5 EC=1.14.-.- Alternative name(s): CYPXXVIIIA5 | ||||
| Gene names |
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| Organism | Drosophila melanogaster (Fruit fly) | ||||
| Taxonomic identifier | 7227 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora |
Protein attributes
| Sequence length | 505 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides By similarity. |
| Catalytic activity | RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O. |
| Cofactor | Heme group By similarity. |
| Subcellular location | Endoplasmic reticulum membrane; Peripheral membrane protein Potential. Microsome membrane; Peripheral membrane protein Potential. |
| Sequence similarities | Belongs to the cytochrome P450 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Endoplasmic reticulum Membrane Microsome |
| Ligand | Heme Iron Metal-binding |
| Molecular function | Monooxygenase Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular component | endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell microsomeInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | electron carrier activity Inferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro monooxygenase activityInferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE014134 Genomic DNA. Translation: AAF53365.1. AY051533 mRNA. Translation: AAK92957.1. |
| RefSeq | NP_609694.1. NM_135850.2. |
| UniGene | Dm.429. |
3D structure databases | |
| ProteinModelPortal | Q9V419. |
| SMR | Q9V419. Positions 24-504. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9V419. |
Proteomic databases | |
| PRIDE | Q9V419. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblMetazoa | FBtr0080587; FBpp0080164; FBgn0028940. |
| GeneID | 34817. |
| KEGG | dme:Dmel_CG8864. |
| NMPDR | fig|7227.3.peg.2364. |
| UCSC | CG8864-RA. d. melanogaster. |
Organism-specific databases | |
| CTD | 34817. |
| FlyBase | FBgn0028940. Cyp28a5. |
Phylogenomic databases | |
| eggNOG | inNOG06203. |
| GeneTree | EMGT00050000001201. |
| InParanoid | Q9V419. |
| OMA | KRHAIYD. |
| OrthoDB | EOG4H44JV. |
| PhylomeDB | Q9V419. |
Gene expression databases | |
| ArrayExpress | Q9V419. |
| Bgee | Q9V419. |
| GermOnline | CG8864. Drosophila melanogaster. |
Family and domain databases | |
| InterPro | IPR001128. Cyt_P450. IPR017972. Cyt_P450_CS. IPR002403. Cyt_P450_E_grp-IV. [Graphical view] |
| Gene3D | G3DSA:1.10.630.10. Cyt_P450. 1 hit. |
| KO | K15005. |
| Pfam | PF00067. p450. 1 hit. [Graphical view] |
| PRINTS | PR00465. EP450IV. PR00385. P450. |
| SUPFAM | SSF48264. Cytochrome_P450. 1 hit. |
| PROSITE | PS00086. CYTOCHROME_P450. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 790365. |
Entry information
| Entry name | C28A5_DROME | ||||||||
| Accession | Primary (citable) accession number: Q9V419 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Drosophila annotation project | ||||||||
Relevant documents
| Drosophila Drosophila: entries, gene names and cross-references to FlyBase |
| SIMILARITY comments Index of protein domains and families |

Clusters with