Unreviewed, UniProtKB/TrEMBL Q9V3V6 (Q9V3V6_DROME)

Names and origin

Protein names

Submitted name:
    Tat-binding protein-1 EMBL AAF56177.1
    EC=3.4.21.-
    EC=3.6.1.3
Submitted name:
    26S proteasome regulatory complex subunit p50 EMBL AAF08386.1
    GH12068p EMBL AAD46823.1

Gene names

Name:	Tbp-1 EMBL AAF56177.1 FlyBase FBgn0028684
ORF Names:	CG10370 FlyBase FBgn0028684, Dmel_CG10370 EMBL AAF56177.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the AAA ATPase family. RuleBase RU003651V0

Ontologies

Keywords
Cellular component	Proteasome
Ligand	ATP-binding RuleBase RU003651V0 Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein catabolic process Inferred from electronic annotation. Source: InterPro proteolysis Ref.5 Inferred from direct assay. Source: FlyBase
Cellular component	cytosol Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: InterPro proteasome regulatory particle Ref.5 Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATPase activity, uncoupled Inferred from electronic annotation. Source: EC endopeptidase activity Ref.5 Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9V3V6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 5635F47A5F57FDAD	FASTA	428	47,807
	10 20 30 40 50 60 MAQTLEDKSI WEDGEESLGE EVMRMSTDEI VSRTRLMDNE IKIMKSEVIR ITHEIQAQNE 70 80 90 100 110 120 KIKDNTEKIK VNKTLPYLVS NVIELLDVDP QEEEDDGSVT VLDNQRKGKC AVIKTSTRQA 130 140 150 160 170 180 YFLPVIGLVD AEKLKPGDLV GVNKDSYLIL ETLPAEYDAR VKAMEVDERP TEQYSDIGGL 190 200 210 220 230 240 DKQIQELIEA VVLPMTHKEK FKNLGIHPPK GVLLYGPPGT GKTLLARACA AQTKSTFLKL 250 260 270 280 290 300 AGPQLVQMFI GDGAKLVRDA FALAKEKAPA IIFIDELDAI GTKRFDSEKA GDREVQRTML 310 320 330 340 350 360 ELLNQLDGFS STADIKVIAA TNRVDILDPA LLRSGRLDRK IEFPHPNEEA RARIMQIHSR 370 380 390 400 410 420 KMNVSNDVNF EELSRSTDDF NGAQCKAVCV EAGMIALRRS ANSVTHEDFM DAIMEVQAKK KANLNYYA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Tsang G., Brokstein P., Frise E., Harvey D., Evans-Holm M., Lewis S.E., Suh C., Rubin G.M. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAD46823.1.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAD46823.1.
[5]	"The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme." Hoelzl H., Kapelari B., Kellermann J., Seemueller E., Suemegi M., Udvardy A., Medalia O., Sperling J., Mueller S.A., Engel A., Baumeister W. J. Cell Biol. 150:119-130(2000) [PubMed: 10893261] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[6]	Hoelzl H. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF160882 mRNA. Translation: AAD46823.1. AF145305 mRNA. Translation: AAF08386.1. AE014297 Genomic DNA. Translation: AAF56177.1.
PIR	T44596.
RefSeq	NP_524464.1.
UniGene	Dm.10261
3D structure databases
HSSP	HSSP built from PDB template 1R7R based on UniProtKB Q01853.
ModBase	Search...
Proteomic databases
PRIDE	Q9V3V6.
Genome annotation databases
Ensembl	FBgn0028684. Drosophila melanogaster. [Contig view]
GeneID	42805.
KEGG	dme:Dmel_CG10370.
NMPDR	fig|7227.3.peg.14284.
Organism-specific databases
FlyBase	FBgn0028684. Tbp-1.
Phylogenomic databases
OMA	Q9V3V6. TLPAEYD.
Enzyme and pathway databases
BRENDA	3.4.25.1. 48.
Gene expression databases
ArrayExpress	Q9V3V6.
Family and domain databases
InterPro	IPR005937. 26S_Psome_P45. IPR003593. ATPase_AAA+_core. IPR003959. ATPase_AAA_core. IPR003960. ATPase_AAA_CS. [Graphical view]
Pfam	PF00004. AAA. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01242. 26Sp45. 1 hit.
PROSITE	PS00674. AAA. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	830660.

Entry information

Entry name

Q9V3V6_DROME

Accession

Primary (citable) accession number: Q9V3V6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)