Unreviewed, UniProtKB/TrEMBL Q9V3J6 (Q9V3J6_DROME)

Names and origin

Protein names

Submitted name:
    Bestrophin 1, isoform A EMBL AAF54503.1
Submitted name:
    Bestrophin 1 EMBL AAR99659.1
    Dbest EMBL AAF32327.1
    LP05915p EMBL AAL29094.1

Gene names

Name:	Best1 EMBL AAF54503.1 FlyBase FBgn0040238
ORF Names:	CG6264 FlyBase FBgn0040238, Dmel_CG6264 EMBL AAF54503.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	721 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequences

	Sequence		Length	Mass (Da)
	Q9V3J6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: B37CD96DE2F15B15	FASTA	721	79,643
	10 20 30 40 50 60 MTITYTGEVA TCRGFGCFLK LLLRWRGSIY KLVWLDLLAF LTIYYAINMV YRFGLNPAQK 70 80 90 100 110 120 ETFEAIVQYC DSYRELIPLS FVLGFYVSIV MTRWWNQYTS IPWPDPIAVF VSSNVHGQDE 130 140 150 160 170 180 RGRMMRRTIM RYVCLCLTMV LANVSPRVKK RFPGLNNLVE AGLLNDNEKT IIETMNKAFP 190 200 210 220 230 240 RPSKHWLPIV WAASIITRAR KEGRIRDDFA VKTIIDELNK FRGQCGLLIS YDTISVPLVY 250 260 270 280 290 300 TQVVTLAVYS YFLTCCMGQQ WTDGKVVGNT TYLNKVDLYF PVFTTLQFFF YMGWLKVAES 310 320 330 340 350 360 LINPFGEDDD DFEVNWMVDR NLQVSYLIVD EMHHDHPELL KDQYWDEVFP NELPYTIAAE 370 380 390 400 410 420 RFRENHPEPS TAKIEVPKNA AMPSTMSSVR IDEMADDASG IHFSAGNGKM RLDSSPSLVS 430 440 450 460 470 480 VSGTLSRVNT VASALKRFLS RDDSRPGSAT PSQDQPYKFP ASASSASLSG AVVGSATSAG 490 500 510 520 530 540 KPAGSLRITQ QVIEEVDEQA TITSMRANDP RPNVMDIFAQ TSSGAGTSGP LQPPPAHSEP 550 560 570 580 590 600 VDIPSRPPSY NRAQSQYEPN LFPPGGVDAL LSTSAPAGGS PLLLSNAATA PSSPVGESSK 610 620 630 640 650 660 SLYDPQKGAS RETVESMDLR SSTDLLGDAA VQPEDEGDDF DKLKAEREKE KLMRQQKNLA 670 680 690 700 710 720 RTISTAPGME ATAVPMVPMV PVNVAVQQAQ LQPVASSADL LAGGDQFSNS TMKSEDAING S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"The vitelliform macular dystrophy protein defines a new family of chloride channels." Sun H., Tsunenari T., Yau K.-W., Nathans J. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL29094.1.
[5]	"dbest, a Drosophila Homolog of Human Bestrophin." Tavsanli B.C., Pappu K., Mardon G. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF218817 mRNA. Translation: AAF32327.1. AE014297 Genomic DNA. Translation: AAF54503.1. AY061546 mRNA. Translation: AAL29094.1. AY515709 mRNA. Translation: AAR99659.1.
RefSeq	NP_652603.1.
UniGene	Dm.3335
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9V3J6. 1 interaction.
Proteomic databases
PRIDE	Q9V3J6.
Genome annotation databases
Ensembl	FBgn0040238. Drosophila melanogaster. [Contig view]
GeneID	53431.
KEGG	dme:Dmel_CG6264.
NMPDR	fig|7227.3.peg.12040.
Organism-specific databases
FlyBase	FBgn0040238. Best1.
Phylogenomic databases
HOGENOM	Q9V3J6.
OMA	Q9V3J6. IVDEMHH.
Gene expression databases
ArrayExpress	Q9V3J6.
Family and domain databases
InterPro	IPR000615. Bestrophin. [Graphical view]
PANTHER	PTHR10736. Bestrophin. 1 hit.
Pfam	PF01062. Bestrophin. 1 hit. [Graphical view]
ProDom	PD002802. Bestrophin. 2 hits. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...
Other Resources
NextBio	841124.

Entry information

Entry name

Q9V3J6_DROME

Accession

Primary (citable) accession number: Q9V3J6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)