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Reviewed, UniProtKB/Swiss-Prot Q9V3G6 (CNOTA_DROME)

Last modified July 7, 2009. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    CCR4-NOT transcription complex subunit 10 homolog
Gene names
ORF Names: CG18616
OrganismDrosophila melanogaster (Fruit fly) [Complete proteome]
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length635 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the CNOT10 family.

Sequence caution

The sequence AAL48085.1 differs from that shown. Reason: Frameshift at position 573.

Ontologies

Keywords
   DomainCoiled coil
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Q9W1C61EBI-170583,EBI-180728

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 635635CCR4-NOT transcription complex subunit 10 homolog
PRO_0000372844

Regions

Coiled coil131 – 16535 Potential

Amino acid modifications

Modified residue451Phosphothreonine

Experimental info

Sequence conflict3471L → F in AAL48085. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q9V3G6-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: CCE078AC0D8E7554

FASTA63569,693
        10         20         30         40         50         60 
MDSAESPTKT QAGEDENYSL LCQAHEQFNN SEFDRCLELL QELETRGESS GPVLRHNRAV 

        70         80         90        100        110        120 
VSYYKTGCTQ HSVLLKELEA LTADADAPGD VSSGLSLKQG AAAATVARYN RAVIYYHRHM 

       130        140        150        160        170        180 
FGTALEKLAP LVARLEALEK AMAALVATLQ LQLLLATNQL NRAEAFLDYL QYKLNLVATA 

       190        200        210        220        230        240 
PSSNAAEEAA VVGTAPPSAA TNSSVVASPG GAAVEGAVPG LGGSLQLLQL ITLVLNRKPV 

       250        260        270        280        290        300 
VIQEDGTPEY AALKAQQYYI MKDFQMAAKQ LMRINNECTQ AGTITPQLST CIANNMGVIH 

       310        320        330        340        350        360 
LRVRHYAIAA KFFQNALNFD QQLARNLRQS TLQTMSSARS CEILYNLGVA MLHLRRPKEA 

       370        380        390        400        410        420 
FQCFLVPVKQ FHSNPRLWLR MAEACIMEHE AKLVEEERQS QSETPSTKPY APQSAGVPEP 

       430        440        450        460        470        480 
TLEFAVLCLR SALTLTQHYK TRFHMAAVSS EDVEAPEPKD PTQESWRHPQ DNNFCNPSKP 

       490        500        510        520        530        540 
VSLESLENMM AAIYAAHSFV SLRLGDHVTA LEMSEKLLAC ERLSDAHKLL GHMYAGEALM 

       550        560        570        580        590        600 
LMDKASEARD HLDPTFVGTL NAFDFETRDW QLKSVDAAQN VVRYNLAVAM ALQNDLPQAK 

       610        620        630 
ALLANLTHSL VANKALALRR FMDLKMGPVP GGTPS 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: GENOME REANNOTATION.
[3]"A Drosophila full-length cDNA resource."
Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E.
Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Berkeley.
Tissue: Embryo.
[4]"An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells."
Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D., Juenger M.A., Eng J.K., Aebersold R., Tao W.A.
Mol. Biosyst. 3:275-286(2007) [PubMed: 17372656] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-45, MASS SPECTROMETRY.

Cross-references

Sequence databases

AE014297 Genomic DNA. Translation: AAF54839.1.
AY070614 mRNA. Translation: AAL48085.1. Frameshift.
RefSeqNP_650215.1.
UniGeneDm.23547

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ9V3G6. 15 interactions.

Proteomic databases

PRIDEQ9V3G6.

Genome annotation databases

EnsemblFBgn0028495. Drosophila melanogaster. [Contig view]
GeneID41552.
KEGGdme:Dmel_CG18616.
NMPDRfig|7227.3.peg.12474.

Organism-specific databases

FlyBaseFBgn0260444. CG18616.

Phylogenomic databases

HOGENOMQ9V3G6.
OMAQ9V3G6. DETTALH.

Gene expression databases

ArrayExpressQ9V3G6.

Family and domain databases

InterProIPR011990. TPR-like_helical.
[Graphical view]
Gene3DG3DSA:1.25.40.10. TPR-like_helical. 1 hit.
ProtoNetSearch...

Other Resources

NextBio824361.

Entry information

Entry nameCNOTA_DROME
AccessionPrimary (citable) accession number: Q9V3G6
Secondary accession number(s): Q8SZP3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: July 7, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectDrosophila annotation project

Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents