Reviewed,
UniProtKB/Swiss-Prot Q9V3D2 (HEM6_DROME)
Last modified
June 16, 2009.
Version 60.
History...
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90%,
50% identity |
Documents (3) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Coproporphyrinogen-III oxidase Short name=Coproporphyrinogenase Short name=Coprogen oxidase Short name=COX EC=1.3.3.3 | ||||
| Gene names |
| ||||
| Organism | Drosophila melanogaster (Fruit fly) [Complete proteome] | ||||
| Taxonomic identifier | 7227 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora |
Protein attributes
| Sequence length | 390 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. |
| Pathway | |
| Sequence similarities | Belongs to the aerobic coproporphyrinogen-III oxidase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Heme biosynthesis Porphyrin biosynthesis |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | heme biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: EC protein bindingInferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 390 | 390 | Coproporphyrinogen-III oxidase | PRO_0000109875 | |||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| AE014134 Genomic DNA. Translation: AAF52469.1. AF160897 mRNA. Translation: AAD46837.1. | |
| RefSeq | NP_524777.1. |
| UniGene | Dm.1822 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:23030N. |
| IntAct | Q9V3D2. 2 interactions. |
Proteomic databases | |
| PRIDE | Q9V3D2. |
Genome annotation databases | |
| Ensembl | FBgn0021944. Drosophila melanogaster. [Contig view] |
| GeneID | 44701. |
| KEGG | dme:Dmel_CG3433. |
| NMPDR | fig|7227.3.peg.1171. |
Organism-specific databases | |
| FlyBase | FBgn0021944. Coprox. |
Phylogenomic databases | |
| HOGENOM | Q9V3D2. |
| OMA | Q9V3D2. VFKPWCD. |
Enzyme and pathway databases | |
| BioCyc | DMEL-XXX-02:DMEL-XXX-02-007763-MON. |
| BRENDA | 1.3.3.3. 48. |
Gene expression databases | |
| ArrayExpress | Q9V3D2. |
| GermOnline | CG3433. Drosophila melanogaster. |
Family and domain databases | |
| InterPro | IPR001260. Coprogen_oxidas. IPR018375. Coproporphyrinogen-3_ox_CS. [Graphical view] |
| Gene3D | G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit. |
| PANTHER | PTHR10755. Coprogen_oxidas. 1 hit. |
| Pfam | PF01218. Coprogen_oxidas. 1 hit. [Graphical view] |
| PIRSF | PIRSF000166. Coproporphyri_ox. 1 hit. |
| PRINTS | PR00073. COPRGNOXDASE. |
| PROSITE | PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 837551. |
Entry information
| Entry name | HEM6_DROME | ||||||||
| Accession | Primary (citable) accession number: Q9V3D2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Drosophila annotation project | ||||||||
Relevant documents
| Drosophila Drosophila: entries, gene names and cross-references to FlyBase |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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