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Q9V2Q9 (CAPPA_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:PYRAB00160
ORF Names:PAB2342
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length469 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 469469Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_0000309611

Sequences

Sequence LengthMass (Da)Tools
Q9V2Q9 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: DB6A6584A7E78BC7

FASTA46953,937
        10         20         30         40         50         60 
MIPRIMSTQH PDNYSIPFFA NSPVLGGEDE ITEAFYAFNV LGADEQMWDF EGKEVDEFVV 

        70         80         90        100        110        120 
KKLLERYPSF FRKVILGKDV RLTPRVPNPT VEKAEAKLLL ETLQGITRAA DYARVFYGED 

       130        140        150        160        170        180 
IAPIFEVILP MTTSLAEIER VHELYRKVVN LADERIYDTT VKEWIGEFYP KEIGIIPLFE 

       190        200        210        220        230        240 
TKVALLKSAK IIGEYLERRE PEYQRVFLAR SDPAMNYGLI SAVTYVKNAL QEIWELEEET 

       250        260        270        280        290        300 
SIPIYPIVGV GGPPFRGGMR PDNVDNVLSE YPSVQTYTVQ SSFKFDYPTK EVVKAVEKVK 

       310        320        330        340        350        360 
STKRKEPYSL EVPDFITLYE VEYQRQVKIL APHIRRLATR IPDRRKRKLH IGLFGYSRNV 

       370        380        390        400        410        420 
GGLSLPRAIK FTASLYSIGV PPELLGLNAL TDRQLDVVSE YYVNIYEDLE FAMRFFSFRV 

       430        440        450        460 
AEKAGLKELV ERIKEFKPEI EEEYVAEAEI VFRGEGDIIK LAQMRGFLG 

« Hide

References

« Hide 'large scale' references
[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.
[2]"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
Gao J., Wang J.
Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ248283 Genomic DNA. Translation: CAB48939.1.
HE613800 Genomic DNA. Translation: CCE69384.1.
PIRD75186.
RefSeqNP_125707.1. NC_000868.1.

3D structure databases

ProteinModelPortalQ9V2Q9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272844.PAB2342.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB48939; CAB48939; PAB2342.
GeneID1495700.
KEGGpab:PAB2342.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHOG000038601.
KOK01595.
OMAPRAIKFT.
ProtClustDBPRK13655.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_PYRAB
AccessionPrimary (citable) accession number: Q9V2Q9
Secondary accession number(s): G8ZFJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families