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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Enzyme and pathway databases

BioCyciPABY272844:G1GT8-20-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:PYRAB00160
ORF Names:PAB2342
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003096111 – 469Phosphoenolpyruvate carboxylaseAdd BLAST469

Proteomic databases

PRIDEiQ9V2Q9

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi272844.PAB2342

Structurei

3D structure databases

ProteinModelPortaliQ9V2Q9
SMRiQ9V2Q9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
HOGENOMiHOG000038601
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

Q9V2Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPRIMSTQH PDNYSIPFFA NSPVLGGEDE ITEAFYAFNV LGADEQMWDF
60 70 80 90 100
EGKEVDEFVV KKLLERYPSF FRKVILGKDV RLTPRVPNPT VEKAEAKLLL
110 120 130 140 150
ETLQGITRAA DYARVFYGED IAPIFEVILP MTTSLAEIER VHELYRKVVN
160 170 180 190 200
LADERIYDTT VKEWIGEFYP KEIGIIPLFE TKVALLKSAK IIGEYLERRE
210 220 230 240 250
PEYQRVFLAR SDPAMNYGLI SAVTYVKNAL QEIWELEEET SIPIYPIVGV
260 270 280 290 300
GGPPFRGGMR PDNVDNVLSE YPSVQTYTVQ SSFKFDYPTK EVVKAVEKVK
310 320 330 340 350
STKRKEPYSL EVPDFITLYE VEYQRQVKIL APHIRRLATR IPDRRKRKLH
360 370 380 390 400
IGLFGYSRNV GGLSLPRAIK FTASLYSIGV PPELLGLNAL TDRQLDVVSE
410 420 430 440 450
YYVNIYEDLE FAMRFFSFRV AEKAGLKELV ERIKEFKPEI EEEYVAEAEI
460
VFRGEGDIIK LAQMRGFLG
Length:469
Mass (Da):53,937
Last modified:May 1, 2000 - v1
Checksum:iDB6A6584A7E78BC7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248283 Genomic DNA Translation: CAB48939.1
HE613800 Genomic DNA Translation: CCE69384.1
PIRiD75186
RefSeqiWP_010867139.1, NC_000868.1

Genome annotation databases

EnsemblBacteriaiCAB48939; CAB48939; PAB2342
GeneIDi1495700
KEGGipab:PAB2342
PATRICifig|272844.11.peg.18

Similar proteinsi

Entry informationi

Entry nameiCAPPA_PYRAB
AccessioniPrimary (citable) accession number: Q9V2Q9
Secondary accession number(s): G8ZFJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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