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Protein

Alpha-amylase

Gene

amyA

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei123NucleophileBy similarity1
Active sitei214Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism

Enzyme and pathway databases

BioCyciPABY272844:G1GT8-195-MONOMER

Protein family/group databases

CAZyiGH57 Glycoside Hydrolase Family 57

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylase (EC:3.2.1.1)
Gene namesi
Name:amyA
Ordered Locus Names:PYRAB01760
ORF Names:PAB0118
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001845721 – 655Alpha-amylaseAdd BLAST655

Proteomic databases

PRIDEiQ9V298

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB0118

Structurei

3D structure databases

ProteinModelPortaliQ9V298
SMRiQ9V298
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 57 family.Curated

Phylogenomic databases

eggNOGiarCOG03280 Archaea
COG1449 LUCA
HOGENOMiHOG000223207
KOiK22451
OMAiHFMSAGL
OrthoDBiPOG093Z00N7

Family and domain databases

Gene3Di2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR015179 A-amylase/a-glucTrfase_C
IPR015178 A-amylase/a-glucTrfase_central
IPR011013 Gal_mutarotase_sf_dom
IPR014718 GH-type_carb-bd
IPR011330 Glyco_hydro/deAcase_b/a-brl
IPR028995 Glyco_hydro_57/38_cen_sf
IPR004300 Glyco_hydro_57_N
PfamiView protein in Pfam
PF09094 DUF1925, 1 hit
PF09095 DUF1926, 1 hit
PF03065 Glyco_hydro_57, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD014405 DUF1925, 1 hit
SUPFAMiSSF74650 SSF74650, 1 hit
SSF88688 SSF88688, 1 hit
SSF88713 SSF88713, 1 hit

Sequencei

Sequence statusi: Complete.

Q9V298-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRINFIFGI HNHQPLGNFG WVMEEAYEKA YRPFLEILEE YPNMKVAIHI
60 70 80 90 100
SGILVEWLEE NKPDYIDLLK SLVRKGQVEI VVAGFYEPVL AAIPKEDRLE
110 120 130 140 150
QIYLLKEWAK KIGYDAKGLW LTERVWQPEL VKTLREAGIE YVVVDDYHFM
160 170 180 190 200
SAGLSKDQLF WPYYTEDGGE VITVFPIDEK LRYLIPFRPV DKVISYLHSL
210 220 230 240 250
ASEDESKVAV FHDDGEKFGI WPMTYEWVYE KGWLREFFDR VSSDEAINIM
260 270 280 290 300
LYSEYLQKFK PKGLVYLPIA SYFEMSEWSL PAQQAKLFVE FVEKLKELNM
310 320 330 340 350
FERYRVFVRG GIWKNFFYKY PEANYMHKRM LMLSRLLRDN PSARRFVLRA
360 370 380 390 400
QCNDAYWHGV FGGIYLPHLR RAIWSNLIKA HSHLEPKNKI LDVDFDGREE
410 420 430 440 450
VFLENDNFII VVKPHYGGSI FELSSKRRAV NYADVIARRW EHYHNLGESE
460 470 480 490 500
SDDNENQEGV SSIHEIGKRI PEDIRKELAY DRYRRGILQD HFFSANETLD
510 520 530 540 550
RYRLAKYWEL GDFIEGVYNY EVGNGLVLWR RGKVLNVTVD VKKSIEVRED
560 570 580 590 600
GFSVRYTVLS EEDIEALFGI ELNIAVHSIK ESPEELIGKR IKVNDKYGVG
610 620 630 640 650
EFEIVLNKKA RIWKYPVKTL SQSEAGWDYI QQGVSYTIIY PINGRLDIEL

YFREL
Length:655
Mass (Da):77,296
Last modified:May 1, 2000 - v1
Checksum:i7F6F920B1A00EECE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248283 Genomic DNA Translation: CAB49100.1
HE613800 Genomic DNA Translation: CCE69552.1
PIRiE75206
RefSeqiWP_010867300.1, NC_000868.1

Genome annotation databases

EnsemblBacteriaiCAB49100; CAB49100; PAB0118
GeneIDi1495063
KEGGipab:PAB0118
PATRICifig|272844.11.peg.190

Similar proteinsi

Entry informationi

Entry nameiAMYA_PYRAB
AccessioniPrimary (citable) accession number: Q9V298
Secondary accession number(s): G8ZG11
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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