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Q9V298

- AMYA_PYRAB

UniProt

Q9V298 - AMYA_PYRAB

Protein

Alpha-amylase

Gene

amyA

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei123 – 1231NucleophileBy similarity
    Active sitei214 – 2141Proton donorBy similarity

    GO - Molecular functioni

    1. alpha-amylase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism

    Protein family/group databases

    CAZyiGH57. Glycoside Hydrolase Family 57.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alpha-amylase (EC:3.2.1.1)
    Gene namesi
    Name:amyA
    Ordered Locus Names:PYRAB01760
    ORF Names:PAB0118
    OrganismiPyrococcus abyssi (strain GE5 / Orsay)
    Taxonomic identifieri272844 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
    ProteomesiUP000000810: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 655655Alpha-amylasePRO_0000184572Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272844.PAB0118.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9V298.
    SMRiQ9V298. Positions 3-655.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 57 family.Curated

    Phylogenomic databases

    eggNOGiCOG1449.
    HOGENOMiHOG000223207.
    KOiK07405.
    OMAiHYHEVPE.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    3.20.110.10. 2 hits.
    InterProiIPR015179. A-amylase/a-glucTrfase_C.
    IPR015178. A-amylase/a-glucTrfase_central.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR011330. Glyco_hydro/deAcase_b/a-brl.
    IPR027291. Glyco_hydro_38/57_N.
    IPR028995. Glyco_hydro_57/38_cen.
    IPR004300. Glyco_hydro_57_N.
    [Graphical view]
    PfamiPF09094. DUF1925. 1 hit.
    PF09095. DUF1926. 1 hit.
    PF03065. Glyco_hydro_57. 1 hit.
    [Graphical view]
    ProDomiPD014405. DUF1925. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF74650. SSF74650. 1 hit.
    SSF88688. SSF88688. 1 hit.
    SSF88713. SSF88713. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9V298-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRINFIFGI HNHQPLGNFG WVMEEAYEKA YRPFLEILEE YPNMKVAIHI    50
    SGILVEWLEE NKPDYIDLLK SLVRKGQVEI VVAGFYEPVL AAIPKEDRLE 100
    QIYLLKEWAK KIGYDAKGLW LTERVWQPEL VKTLREAGIE YVVVDDYHFM 150
    SAGLSKDQLF WPYYTEDGGE VITVFPIDEK LRYLIPFRPV DKVISYLHSL 200
    ASEDESKVAV FHDDGEKFGI WPMTYEWVYE KGWLREFFDR VSSDEAINIM 250
    LYSEYLQKFK PKGLVYLPIA SYFEMSEWSL PAQQAKLFVE FVEKLKELNM 300
    FERYRVFVRG GIWKNFFYKY PEANYMHKRM LMLSRLLRDN PSARRFVLRA 350
    QCNDAYWHGV FGGIYLPHLR RAIWSNLIKA HSHLEPKNKI LDVDFDGREE 400
    VFLENDNFII VVKPHYGGSI FELSSKRRAV NYADVIARRW EHYHNLGESE 450
    SDDNENQEGV SSIHEIGKRI PEDIRKELAY DRYRRGILQD HFFSANETLD 500
    RYRLAKYWEL GDFIEGVYNY EVGNGLVLWR RGKVLNVTVD VKKSIEVRED 550
    GFSVRYTVLS EEDIEALFGI ELNIAVHSIK ESPEELIGKR IKVNDKYGVG 600
    EFEIVLNKKA RIWKYPVKTL SQSEAGWDYI QQGVSYTIIY PINGRLDIEL 650
    YFREL 655
    Length:655
    Mass (Da):77,296
    Last modified:May 1, 2000 - v1
    Checksum:i7F6F920B1A00EECE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ248283 Genomic DNA. Translation: CAB49100.1.
    HE613800 Genomic DNA. Translation: CCE69552.1.
    PIRiE75206.
    RefSeqiNP_125869.1. NC_000868.1.

    Genome annotation databases

    EnsemblBacteriaiCAB49100; CAB49100; PAB0118.
    GeneIDi1495063.
    KEGGipab:PAB0118.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ248283 Genomic DNA. Translation: CAB49100.1 .
    HE613800 Genomic DNA. Translation: CCE69552.1 .
    PIRi E75206.
    RefSeqi NP_125869.1. NC_000868.1.

    3D structure databases

    ProteinModelPortali Q9V298.
    SMRi Q9V298. Positions 3-655.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272844.PAB0118.

    Protein family/group databases

    CAZyi GH57. Glycoside Hydrolase Family 57.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB49100 ; CAB49100 ; PAB0118 .
    GeneIDi 1495063.
    KEGGi pab:PAB0118.

    Phylogenomic databases

    eggNOGi COG1449.
    HOGENOMi HOG000223207.
    KOi K07405.
    OMAi HYHEVPE.

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    3.20.110.10. 2 hits.
    InterProi IPR015179. A-amylase/a-glucTrfase_C.
    IPR015178. A-amylase/a-glucTrfase_central.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR011330. Glyco_hydro/deAcase_b/a-brl.
    IPR027291. Glyco_hydro_38/57_N.
    IPR028995. Glyco_hydro_57/38_cen.
    IPR004300. Glyco_hydro_57_N.
    [Graphical view ]
    Pfami PF09094. DUF1925. 1 hit.
    PF09095. DUF1926. 1 hit.
    PF03065. Glyco_hydro_57. 1 hit.
    [Graphical view ]
    ProDomi PD014405. DUF1925. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF74650. SSF74650. 1 hit.
    SSF88688. SSF88688. 1 hit.
    SSF88713. SSF88713. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GE5 / Orsay.
    2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
      Gao J., Wang J.
      Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: GE5 / Orsay.

    Entry informationi

    Entry nameiAMYA_PYRAB
    AccessioniPrimary (citable) accession number: Q9V298
    Secondary accession number(s): G8ZG11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2001
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3