Q9V1U4 (RNP1_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	PYRAB03330
ORF Names:	PAB2126

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 127	127	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_0000128435

Sequences

	Sequence		Length	Mass (Da)
	Q9V1U4 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 6048763F6582C9A0	FASTA	127	14,970
	10 20 30 40 50 60 MRRNGKERKD RTSGGSQRPY QEIVGRTWIF RGSHRGRVTK RNIIWHELIG LKVRVVNSMH 70 80 90 100 110 120 PGFVGIEGYV VDETRNMLVI VGDKVWKVPK DVCIFEFETE DGAKIKIPGE RLVGRPEMRL KKRWRKW

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248284 Genomic DNA. Translation: CAB49255.1.
PIR	H75146.
RefSeq	NP_126024.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9V1U4.
SMR	Q9V1U4. Positions 36-127.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002269; EBPYRP00000002200; EBPYRG00000002269.
GeneID	1495223.
GenomeReviews	Gene locus PYRAB03330 in contig AL096836_GR.
KEGG	pab:PAB2126.
NMPDR	fig|272844.1.peg.347.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023214.
HOGENOM	HBG704950.
OMA	ISTKGRV.
ProtClustDB	PRK03879.
Enzyme and pathway databases
BioCyc	PABY272844:PAB2126-MONOMER.
Family and domain databases
HAMAP	MF_00754. RNase_P_1. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
KO	K03538.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SMART	SM00538. POP4. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_PYRAB

Accession

Primary (citable) accession number: Q9V1U4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2004
Last sequence update:	May 1, 2000
Last modified:	November 16, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program