ID   Q9V1Q2_PYRAB            Unreviewed;       183 AA.
AC   Q9V1Q2;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Adenylate cyclase 2 {ECO:0000313|EMBL:CAB49297.1};
DE   SubName: Full=Adenylyl cyclase related protein {ECO:0000313|EMBL:CCE69752.1};
GN   OrderedLocusNames=PAB2098 {ECO:0000313|EMBL:CAB49297.1};
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844 {ECO:0000313|EMBL:CAB49297.1, ECO:0000313|Proteomes:UP000000810};
RN   [1] {ECO:0000313|EMBL:CAB49297.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Orsay {ECO:0000313|EMBL:CAB49297.1};
RA   Genoscope;
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAB49297.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Orsay {ECO:0000313|EMBL:CAB49297.1};
RX   PubMed=10736225; DOI=10.1006/jmbi.2000.3593;
RA   Gaspin C., Cavaille J., Erauso G.;
RT   "Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs:
RT   lessons from the Pyrococcus genomes.";
RL   J. Mol. Biol. 297:895-906(2000).
RN   [3] {ECO:0000313|EMBL:CAB49297.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Orsay {ECO:0000313|EMBL:CAB49297.1};
RX   PubMed=11381026; DOI=10.1101/gr.GR1653R;
RA   Lecompte O., Ripp R., Puzos-Barbe V., Duprat S., Heilig R., Dietrich J.,
RA   Thierry J.C., Poch O.;
RT   "Genome evolution at the genus level: comparison of three complete genomes
RT   of hyperthermophilic archaea.";
RL   Genome Res. 11:981-993(2001).
RN   [4] {ECO:0000313|EMBL:CAB49297.1, ECO:0000313|Proteomes:UP000000810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay {ECO:0000313|Proteomes:UP000000810}, and Orsay
RC   {ECO:0000313|EMBL:CAB49297.1};
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G., Barbe V., Flament D., Galperin M., Heilig R., Ripp R.,
RA   Lecompte O., Prieur D., Poch O., Quellerou J., Thierry J.C.,
RA   Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [5] {ECO:0000313|EMBL:CCE69752.1, ECO:0000313|Proteomes:UP000009139}
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 {ECO:0000313|EMBL:CCE69752.1}, and GE5 / Orsay
RC   {ECO:0000313|Proteomes:UP000009139};
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
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DR   EMBL; AJ248284; CAB49297.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE69752.1; -; Genomic_DNA.
DR   PIR; B75152; B75152.
DR   RefSeq; WP_010867497.1; NC_000868.1.
DR   AlphaFoldDB; Q9V1Q2; -.
DR   STRING; 272844.PAB2098; -.
DR   GeneID; 1495265; -.
DR   KEGG; pab:PAB2098; -.
DR   eggNOG; arCOG01723; Archaea.
DR   HOGENOM; CLU_105244_2_0_2; -.
DR   OrthoDB; 46040at2157; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   CDD; cd07890; CYTH-like_AC_IV-like; 1.
DR   Gene3D; 2.40.320.10; Hypothetical Protein Pfu-838710-001; 1.
DR   InterPro; IPR008173; Adenylyl_cyclase_CyaB.
DR   InterPro; IPR033469; CYTH-like_dom_sf.
DR   InterPro; IPR023577; CYTH_domain.
DR   NCBIfam; TIGR00318; cyaB; 1.
DR   PANTHER; PTHR21028:SF2; CYTH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR21028; SI:CH211-156B7.4; 1.
DR   Pfam; PF01928; CYTH; 1.
DR   SMART; SM01118; CYTH; 1.
DR   SUPFAM; SSF55154; CYTH-like phosphatases; 1.
DR   PROSITE; PS51707; CYTH; 1.
PE   4: Predicted;
FT   DOMAIN          1..175
FT                   /note="CYTH"
FT                   /evidence="ECO:0000259|PROSITE:PS51707"
SQ   SEQUENCE   183 AA;  22162 MW;  FAA06266BAC4B91A CRC64;
     MYEVELKGYA NEEIFEKVRE TYRFMRREIH EDIYYQHPCR DFSKTDEALR IRIKRFNGHH
     EVFLTYKGPK LDKRSKTRLE IEVEIQDTEK YFQLLQNLGF REVLRIVKTR EKYYVDKGIT
     ITLDEVEGLG KFIEIETLVK EKEEIPRTVE KLEGILRNLG VERFERKSYL ELLLEASQKS
     HHT
//