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Q9V1P5

- XERCL_PYRAB

UniProt

Q9V1P5 - XERCL_PYRAB

Protein

Probable tyrosine recombinase XerC-like

Gene

PYRAB03820

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei135 – 1351UniRule annotation
    Active sitei160 – 1601UniRule annotation
    Active sitei226 – 2261UniRule annotation
    Active sitei229 – 2291UniRule annotation
    Active sitei252 – 2521UniRule annotation
    Active sitei261 – 2611O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. chromosome segregation Source: UniProtKB-HAMAP
    2. transposition, DNA-mediated Source: UniProtKB-HAMAP

    Keywords - Biological processi

    DNA integration, DNA recombination

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable tyrosine recombinase XerC-likeUniRule annotation
    Gene namesi
    Ordered Locus Names:PYRAB03820
    ORF Names:PAB0255
    OrganismiPyrococcus abyssi (strain GE5 / Orsay)
    Taxonomic identifieri272844 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
    ProteomesiUP000000810: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 286286Probable tyrosine recombinase XerC-likePRO_0000095355Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272844.PAB0255.

    Structurei

    Secondary structure

    1
    286
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi11 – 2212
    Helixi27 – 4317
    Helixi49 – 6214
    Helixi66 – 8318
    Helixi86 – 916
    Helixi107 – 1159
    Helixi120 – 13112
    Helixi136 – 1416
    Helixi144 – 1463
    Turni149 – 1524
    Beta strandi153 – 1564
    Beta strandi160 – 1623
    Beta strandi165 – 1684
    Helixi171 – 18212
    Beta strandi189 – 1913
    Beta strandi200 – 2023
    Helixi205 – 21814
    Helixi225 – 23814
    Helixi243 – 2508
    Helixi265 – 2728
    Turni273 – 2786

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4A8EX-ray2.99A1-286[»]
    ProteinModelPortaliQ9V1P5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0582.
    HOGENOMiHOG000045296.
    KOiK04763.
    OMAiDDINLEH.

    Family and domain databases

    Gene3Di1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPiMF_01808. Recomb_XerC.
    InterProiIPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR010998. Integrase_Lambda-type_N.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view]
    PfamiPF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view]
    SUPFAMiSSF47823. SSF47823. 1 hit.
    SSF56349. SSF56349. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9V1P5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEREERVRD DTIEEFATYL ELEGKSRNTV RMYTYYISKF FEEGHSPTAR    50
    DALRFLAKLK RKGYSTRSLN LVIQALKAYF KFEGLDSEAE KLKTPKMPKT 100
    LPKSLTEEEV RRIINAAETL RDRLILLLLY GAGLRVSELC NLRVEDVNFE 150
    YGVIVVRGGK GGKDRVVPIS ESLLSEIKRY LESRNDDSPY LFVEMKRKRK 200
    DKLSPKTVWR LVKKYGRKAG VELTPHQLRH SFATHMLERG IDIRIIQELL 250
    GHSNLSTTQI YTKVSTKHLK EAVKKAKLVE SIIGGS 286
    Length:286
    Mass (Da):33,025
    Last modified:May 1, 2000 - v1
    Checksum:iC44A99CB3F75A0E2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ248284 Genomic DNA. Translation: CAB49304.1.
    HE613800 Genomic DNA. Translation: CCE69759.1.
    PIRiA75153.
    RefSeqiNP_126073.1. NC_000868.1.

    Genome annotation databases

    EnsemblBacteriaiCAB49304; CAB49304; PAB0255.
    GeneIDi1495272.
    KEGGipab:PAB0255.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ248284 Genomic DNA. Translation: CAB49304.1 .
    HE613800 Genomic DNA. Translation: CCE69759.1 .
    PIRi A75153.
    RefSeqi NP_126073.1. NC_000868.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4A8E X-ray 2.99 A 1-286 [» ]
    ProteinModelPortali Q9V1P5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272844.PAB0255.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB49304 ; CAB49304 ; PAB0255 .
    GeneIDi 1495272.
    KEGGi pab:PAB0255.

    Phylogenomic databases

    eggNOGi COG0582.
    HOGENOMi HOG000045296.
    KOi K04763.
    OMAi DDINLEH.

    Family and domain databases

    Gene3Di 1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPi MF_01808. Recomb_XerC.
    InterProi IPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR010998. Integrase_Lambda-type_N.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view ]
    Pfami PF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47823. SSF47823. 1 hit.
    SSF56349. SSF56349. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GE5 / Orsay.
    2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
      Gao J., Wang J.
      Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: GE5 / Orsay.

    Entry informationi

    Entry nameiXERCL_PYRAB
    AccessioniPrimary (citable) accession number: Q9V1P5
    Secondary accession number(s): G8ZI16
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3