Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable tyrosine recombinase XerC-like

Gene

PYRAB03820

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei135 – 1351UniRule annotation
Active sitei160 – 1601UniRule annotation
Active sitei226 – 2261UniRule annotation
Active sitei229 – 2291UniRule annotation
Active sitei252 – 2521UniRule annotation
Active sitei261 – 2611O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. chromosome segregation Source: UniProtKB-HAMAP
  2. transposition, DNA-mediated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA integration, DNA recombination

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine recombinase XerC-likeUniRule annotation
Gene namesi
Ordered Locus Names:PYRAB03820
ORF Names:PAB0255
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000810: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 286286Probable tyrosine recombinase XerC-likePRO_0000095355Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB0255.

Structurei

Secondary structure

1
286
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi11 – 2212Combined sources
Helixi27 – 4317Combined sources
Helixi49 – 6214Combined sources
Helixi66 – 8318Combined sources
Helixi86 – 916Combined sources
Helixi107 – 1159Combined sources
Helixi120 – 13112Combined sources
Helixi136 – 1416Combined sources
Helixi144 – 1463Combined sources
Turni149 – 1524Combined sources
Beta strandi153 – 1564Combined sources
Beta strandi160 – 1623Combined sources
Beta strandi165 – 1684Combined sources
Helixi171 – 18212Combined sources
Beta strandi189 – 1913Combined sources
Beta strandi200 – 2023Combined sources
Helixi205 – 21814Combined sources
Helixi225 – 23814Combined sources
Helixi243 – 2508Combined sources
Helixi265 – 2728Combined sources
Turni273 – 2786Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4A8EX-ray2.99A1-286[»]
ProteinModelPortaliQ9V1P5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0582.
HOGENOMiHOG000045296.
KOiK04763.
OMAiKSPNTIR.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR010998. Integrase_Lambda-type_N.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF47823. SSF47823. 1 hit.
SSF56349. SSF56349. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9V1P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEREERVRD DTIEEFATYL ELEGKSRNTV RMYTYYISKF FEEGHSPTAR
60 70 80 90 100
DALRFLAKLK RKGYSTRSLN LVIQALKAYF KFEGLDSEAE KLKTPKMPKT
110 120 130 140 150
LPKSLTEEEV RRIINAAETL RDRLILLLLY GAGLRVSELC NLRVEDVNFE
160 170 180 190 200
YGVIVVRGGK GGKDRVVPIS ESLLSEIKRY LESRNDDSPY LFVEMKRKRK
210 220 230 240 250
DKLSPKTVWR LVKKYGRKAG VELTPHQLRH SFATHMLERG IDIRIIQELL
260 270 280
GHSNLSTTQI YTKVSTKHLK EAVKKAKLVE SIIGGS
Length:286
Mass (Da):33,025
Last modified:May 1, 2000 - v1
Checksum:iC44A99CB3F75A0E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248284 Genomic DNA. Translation: CAB49304.1.
HE613800 Genomic DNA. Translation: CCE69759.1.
PIRiA75153.
RefSeqiNP_126073.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB49304; CAB49304; PAB0255.
GeneIDi1495272.
KEGGipab:PAB0255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248284 Genomic DNA. Translation: CAB49304.1.
HE613800 Genomic DNA. Translation: CCE69759.1.
PIRiA75153.
RefSeqiNP_126073.1. NC_000868.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4A8EX-ray2.99A1-286[»]
ProteinModelPortaliQ9V1P5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272844.PAB0255.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB49304; CAB49304; PAB0255.
GeneIDi1495272.
KEGGipab:PAB0255.

Phylogenomic databases

eggNOGiCOG0582.
HOGENOMiHOG000045296.
KOiK04763.
OMAiKSPNTIR.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR010998. Integrase_Lambda-type_N.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF47823. SSF47823. 1 hit.
SSF56349. SSF56349. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / Orsay.
  2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
    Gao J., Wang J.
    Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GE5 / Orsay.

Entry informationi

Entry nameiXERCL_PYRAB
AccessioniPrimary (citable) accession number: Q9V1P5
Secondary accession number(s): G8ZI16
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: May 1, 2000
Last modified: February 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.