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Q9V1P5 (XERCL_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine recombinase XerC-like
Gene names
Ordered Locus Names:PYRAB03820
ORF Names:PAB0255
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules By similarity. HAMAP-Rule MF_01808

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01808.

Sequence similarities

Belongs to the 'phage' integrase family. XerC subfamily.

Ontologies

Keywords
   Biological processDNA integration
DNA recombination
   Cellular componentCytoplasm
   LigandDNA-binding
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processchromosome segregation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

transposition, DNA-mediated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

tyrosine-based site-specific recombinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Probable tyrosine recombinase XerC-like HAMAP-Rule MF_01808
PRO_0000095355

Sites

Active site1351 By similarity
Active site1601 By similarity
Active site2261 By similarity
Active site2291 By similarity
Active site2521 By similarity
Active site2611O-(3'-phospho-DNA)-tyrosine intermediate By similarity

Secondary structure

......................................... 286
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9V1P5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: C44A99CB3F75A0E2

FASTA28633,025
        10         20         30         40         50         60 
MEEREERVRD DTIEEFATYL ELEGKSRNTV RMYTYYISKF FEEGHSPTAR DALRFLAKLK 

        70         80         90        100        110        120 
RKGYSTRSLN LVIQALKAYF KFEGLDSEAE KLKTPKMPKT LPKSLTEEEV RRIINAAETL 

       130        140        150        160        170        180 
RDRLILLLLY GAGLRVSELC NLRVEDVNFE YGVIVVRGGK GGKDRVVPIS ESLLSEIKRY 

       190        200        210        220        230        240 
LESRNDDSPY LFVEMKRKRK DKLSPKTVWR LVKKYGRKAG VELTPHQLRH SFATHMLERG 

       250        260        270        280 
IDIRIIQELL GHSNLSTTQI YTKVSTKHLK EAVKKAKLVE SIIGGS 

« Hide

References

« Hide 'large scale' references
[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.
[2]"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
Gao J., Wang J.
Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GE5 / Orsay.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ248284 Genomic DNA. Translation: CAB49304.1.
HE613800 Genomic DNA. Translation: CCE69759.1.
PIRA75153.
RefSeqNP_126073.1. NC_000868.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4A8EX-ray2.99A1-286[»]
ProteinModelPortalQ9V1P5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272844.PAB0255.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB49304; CAB49304; PAB0255.
GeneID1495272.
KEGGpab:PAB0255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0582.
HOGENOMHOG000045296.
KOK04763.
OMAANISIDF.
ProtClustDBCLSK340523.

Family and domain databases

Gene3D1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPMF_01808. Recomb_XerC.
InterProIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR010998. Integrase_Lambda-type_N.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMSSF47823. SSF47823. 1 hit.
SSF56349. SSF56349. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXERCL_PYRAB
AccessionPrimary (citable) accession number: Q9V1P5
Secondary accession number(s): G8ZI16
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references