Q9V1I8 (Q9V1I8_PYRAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LeuB-2 3-isopropylmalate dehydrogenase EMBL CAB49361.1

Gene names

Name:	leuB-2 EMBL CAB49361.1
Ordered Locus Names:	PYRAB04390
ORF Names:	PAB0289 EMBL CAB49361.1

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP] EMBL CAB49361.1

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	leucine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	3-isopropylmalate dehydrogenase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9V1I8 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: CCA88BAE89FB0B2E	FASTA	346	38,575
	10 20 30 40 50 60 MYRVAVIKGD GIGPEVVDSA IRVVNSVTDR IRFYEFEGGF EVFKRIGSPI SEDDLKEIRK 70 80 90 100 110 120 MDAILFGATT TPFNVPGYRS LIVTLRKELD LYANLRIIPD LSNGKEIVIV RENTEGLYAR 130 140 150 160 170 180 DGIGFSDRAI DFRIITLEGA RRIAKFAINL AKERNSFITF VHKANVLKGD RFFREIVLEI 190 200 210 220 230 240 AEREGVEVRE AIIDSFMIKL VKNPWDHGVI LTENMFGDII SDLATIHAGS IGIVPSGNYG 250 260 270 280 290 300 DEIALFEPIH GSAPDIAGKG IANPIGAILS AAMMLDYLGL NGKVVWEATR RYVRYGNLTP 310 320 330 340 DMGGTATTSE VTKGIISEIY SFDPFDIDEI WVEEIRLGRI PLTLWR

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248284 Genomic DNA. Translation: CAB49361.1.
PIR	B75160.
RefSeq	NP_126130.1. NC_000868.1.
3D structure databases
HSSP	HSSP built from PDB template 2AYQ based on UniProtKB P12010.
ProteinModelPortal	Q9V1I8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002937; EBPYRP00000002868; EBPYRG00000002937.
GeneID	1495333.
GenomeReviews	Gene locus PYRAB04390 in contig AL096836_GR.
KEGG	pab:PAB0289.
NMPDR	fig|272844.1.peg.457.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022922.
HOGENOM	HBG518924.
OMA	HAGSIGI.
PhylomeDB	Q9V1I8.
ProtClustDB	PRK00772.
Enzyme and pathway databases
BioCyc	PABY272844:PAB0289-MONOMER.
Family and domain databases
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR001804. Isocitrate/isopropylmalate_DH. IPR024084. IsoPropMal-DH-like_dom. IPR011828. LEU3_arc. [Graphical view]
Gene3D	G3DSA:3.40.718.10. IDH_IMDH. 1 hit.
KO	K00052.
PANTHER	PTHR11835. IDH_IMDH_dimeric. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR02088. LEU3_arch. 1 hit.
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9V1I8_PYRAB

Accession

Primary (citable) accession number: Q9V1I8

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)