Q9V116 (RPOH_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit H
EC=2.7.7.6

Gene names

Name:	rpoH
Ordered Locus Names:	PYRAB06130
ORF Names:	PAB7151

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	82 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00025
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00025
Sequence similarities	Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 82	82	DNA-directed RNA polymerase subunit H HAMAP MF_00025		PRO_0000146098

Sequences

	Sequence		Length	Mass (Da)
	Q9V116 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: DB9D315A7FE63902	FASTA	82	9,284
	10 20 30 40 50 60 MAGKSEFNIF KHVLVPEHRI LSEEEKKALL EKYRITPAQL PQIKASDPAV KALGAKPGDI 70 80 IEIKRKSPTA GVYYYYRVVV ED

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248284 Genomic DNA. Translation: CAB49535.1.
PIR	H75181.
RefSeq	NP_126304.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9V116.
SMR	Q9V116. Positions 6-81.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000003364; EBPYRP00000003295; EBPYRG00000003364.
GeneID	1495518.
GenomeReviews	Gene locus PYRAB06130 in contig AL096836_GR.
KEGG	pab:PAB7151.
NMPDR	fig|272844.1.peg.642.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023233.
HOGENOM	HBG496846.
OMA	EHELVPK.
ProtClustDB	PRK09570.
Enzyme and pathway databases
BioCyc	PABY272844:PAB7151-MONOMER.
Family and domain databases
HAMAP	MF_00025. RNApol_arch_H. [Tree]
InterPro	IPR020609. DNA-dir_RNA_pol_subH/Rpb5_arc. IPR000783. RNA_pol_subH/Rpb5_C. IPR020608. RNA_pol_subH/Rpb5_CS. [Graphical view]
Gene3D	G3DSA:3.90.940.20. RNApol_RPB5. 1 hit.
KO	K03053.
Pfam	PF01191. RNA_pol_Rpb5_C. 1 hit. [Graphical view]
ProDom	PD005155. RNA_pol_subH/Rpb5_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF55287. RNApol_RPB5_like. 1 hit.
PROSITE	PS01110. RNA_POL_H_23KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOH_PYRAB

Accession

Primary (citable) accession number: Q9V116

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	May 1, 2000
Last modified:	November 16, 2011
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program