Q9V0V4 (RNP2_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	PYRAB06860
ORF Names:	PAB0467

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus › Pyrococcus abyssi

Protein attributes

Sequence length	118 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
Sequence caution	The sequence CAB49599.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 118	118	Ribonuclease P protein component 2 HAMAP-Rule MF_00755		PRO_0000140025

Sequences

	Sequence		Length	Mass (Da)
	Q9V0V4 [UniParc]. Last modified May 16, 2012. Version 2. Checksum: 4C691C6DFC540E6E	FASTA	118	13,780
	10 20 30 40 50 60 MKLKTLPPTL RDKNRYIAFE IISDDEFTKD EVKSLIWEAS LRVLGELGTA LAKPWFIKYD 70 80 90 100 110 PKTKTGIVRC DREYVEHLRF ALMLATDFNG KRLIIRTLGV SGTIKRLKKK FLSQYGWK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.
[2]	"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638." Gao J., Wang J. Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248285 Genomic DNA. Translation: CAB49599.1. Different initiation. HE613800 Genomic DNA. Translation: CCE70075.1.
PIR	F75110.
RefSeq	NP_126368.1. NC_000868.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	272844.PAB0467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAB49599; CAB49599; PAB0467.
GeneID	1495588.
KEGG	pab:PAB0467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1369.
HOGENOM	HOG000286243.
KO	K03537.
OMA	NPWLIDY.
ProtClustDB	PRK03717.
Family and domain databases
HAMAP	MF_00755. RNase_P_2.
InterPro	IPR002759. RNase_P/MRP_subunit. IPR016434. RNase_P_comp-2. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_PYRAB

Accession

Primary (citable) accession number: Q9V0V4
Secondary accession number(s): G8ZJE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	May 16, 2012
Last modified:	May 1, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program