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Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:PYRAB06860
ORF Names:PAB0467
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001400251 – 118Ribonuclease P protein component 2Add BLAST118

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi272844.PAB0467.

Structurei

3D structure databases

SMRiQ9V0V4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01365. Archaea.
COG1369. LUCA.
HOGENOMiHOG000286243.
KOiK03537.
OMAiNPWLIDY.
OrthoDBiPOG093Z0EPO.

Family and domain databases

HAMAPiMF_00755. RNase_P_2. 1 hit.
InterProiView protein in InterPro
IPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
PfamiView protein in Pfam
PF01900. RNase_P_Rpp14. 1 hit.
PIRSFiPIRSF004952. RNase_P_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9V0V4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKTLPPTL RDKNRYIAFE IISDDEFTKD EVKSLIWEAS LRVLGELGTA
60 70 80 90 100
LAKPWFIKYD PKTKTGIVRC DREYVEHLRF ALMLATDFNG KRLIIRTLGV
110
SGTIKRLKKK FLSQYGWK
Length:118
Mass (Da):13,780
Last modified:May 16, 2012 - v2
Checksum:i4C691C6DFC540E6E
GO

Sequence cautioni

The sequence CAB49599 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248285 Genomic DNA. Translation: CAB49599.1. Different initiation.
HE613800 Genomic DNA. Translation: CCE70075.1.
PIRiF75110.
RefSeqiWP_048146610.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB49599; CAB49599; PAB0467.
GeneIDi1495588.
KEGGipab:PAB0467.
PATRICifig|272844.11.peg.720.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRNP2_PYRAB
AccessioniPrimary (citable) accession number: Q9V0V4
Secondary accession number(s): G8ZJE8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: May 16, 2012
Last modified: June 7, 2017
This is version 81 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families