Q9V0L6 (RPIA_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Synonyms:	rpi
Ordered Locus Names:	PYRAB07730
ORF Names:	PAB0522

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 229	229	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158515

Sequences

	Sequence		Length	Mass (Da)
	Q9V0L6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 43DC479270F68F04	FASTA	229	24,986
	10 20 30 40 50 60 MNIEEMKKIA AKEALKFIED DMVIGLGTGS TTAYFIRLLG DMIKKGEVSD IVGVPTSYQS 70 80 90 100 110 120 RLLAIESGIP VATLDQVDAI DVAVDGADEV DPNLNLIKGR GAALTMEKII ESRAGMFIVL 130 140 150 160 170 180 VDERKLVDYL CQKMPVPIEV IPQAWRAIVE ELSIFNAEAK LRMGVNKDGP VITDNGNFII 190 200 210 220 DAKFPRIDDP LDMEIELNTI PGVVENGIFA DIADIVIVGT KEGVKTLER

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248285 Genomic DNA. Translation: CAB49687.1.
PIR	F75121.
RefSeq	NP_126456.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9V0L6.
SMR	Q9V0L6. Positions 1-229.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002381; EBPYRP00000002312; EBPYRG00000002381.
GeneID	1496113.
GenomeReviews	Gene locus PYRAB07730 in contig AL096836_GR.
KEGG	pab:PAB0522.
NMPDR	fig|272844.1.peg.806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022434.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	Q9V0L6.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	PABY272844:PAB0522-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_PYRAB

Accession

Primary (citable) accession number: Q9V0L6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2001
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program