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Protein

Aspartate aminotransferase

Gene

aspC

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei34Aspartate; via amide nitrogenBy similarity1
Binding sitei171AspartateBy similarity1
Binding sitei362AspartateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciPABY272844:G1GT8-842-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase (EC:2.6.1.1)
Short name:
AspAT
Alternative name(s):
Transaminase A
Gene namesi
Name:aspC
Ordered Locus Names:PYRAB07770
ORF Names:PAB0525
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001238601 – 389Aspartate aminotransferaseAdd BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei233N6-(pyridoxal phosphate)lysineBy similarity1

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi272844.PAB0525

Structurei

3D structure databases

ProteinModelPortaliQ9V0L2
SMRiQ9V0L2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01130 Archaea
COG0436 LUCA
HOGENOMiHOG000223062
KOiK10907
OMAiDFVTPWH
OrthoDBiPOG093Z02O6

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR004838 NHTrfase_class1_PyrdxlP-BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00105 AA_TRANSFER_CLASS_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9V0L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMSDRLDLV NPSEIRKLFD IAAGMKDVIS LGIGEPDFDT PQHIKEYAKE
60 70 80 90 100
ALDMGLTHYG PNIGLPELRE AIAEKLKKQN NIEADPNKEI MVLVGANQAF
110 120 130 140 150
LMGLSAFLKD GEEVLIPTPA FVSYAPAVIL AGGKPVEVPT YEENEFRLNV
160 170 180 190 200
DELKKYVTEK TKALIINSPC NPTGSVLKKK DLEEIADFAV EHDLIVISDE
210 220 230 240 250
VYEHFIYDDV KHYSIASLDG MFERTITVNG FSKTFAMTGW RLGFVAAPSW
260 270 280 290 300
IIEKMVKFQM YNATCPVTFI QYAAAKALRD ERSWKAVEEM RKEYDRRRKL
310 320 330 340 350
VWKRLNEMGL PTVKPKGAFY IFPRIKDTGL TSKEFSELML MEAKVAVVPG
360 370 380
SAFGKAGEGY VRISYATAYE KLEEAMDRME KVLREKKLT
Length:389
Mass (Da):43,923
Last modified:May 1, 2000 - v1
Checksum:iAC811F1A171A513C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248285 Genomic DNA Translation: CAB49691.1
HE613800 Genomic DNA Translation: CCE70174.1
PIRiB75122
RefSeqiWP_010867899.1, NC_000868.1

Genome annotation databases

EnsemblBacteriaiCAB49691; CAB49691; PAB0525
GeneIDi1496118
KEGGipab:PAB0525
PATRICifig|272844.11.peg.817

Similar proteinsi

Entry informationi

Entry nameiAAT_PYRAB
AccessioniPrimary (citable) accession number: Q9V0L2
Secondary accession number(s): G8ZGX9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health