Reviewed, UniProtKB/Swiss-Prot Q9V035 (AOR_PYRAB)

Names and origin

Protein names

Recommended name:
    Tungsten-containing aldehyde ferredoxin oxidoreductase
    EC=1.2.7.5

Gene names

Name:	aor
Ordered Locus Names:	PYRAB09630
ORF Names:	PAB0647

Organism

Pyrococcus abyssi [Complete proteome] [HAMAP]

Taxonomic identifier

29292 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	607 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.
Cofactor	Binds 1 4Fe-4S cluster per subunit By similarity. Binds 1 tungstopterin cofactor per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the AOR/FOR family.

Ontologies

Keywords
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding Tungsten
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW aldehyde ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 607	607	Tungsten-containing aldehyde ferredoxin oxidoreductase		PRO_0000064605

Sequences

	Sequence		Length	Mass (Da)
	Q9V035-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 5CC3135C6E622505	FASTA	607	67,520
	10 20 30 40 50 60 MFGYWGKILR VNLTDGTIKE ETFNEEFAKK WLGTRGFGIY FLLKEMDPKV DPFSPENKLI 70 80 90 100 110 120 FATGPLTGTS APTGGRYMVI TKSPLTGYIA MANSGGYFGA ELKFAGWDAI IIEGKADHPV 130 140 150 160 170 180 YLYIHDENVE IRDASKVWGK LVSETEKALK EEVGDKHVQI ASIGPAGENK VRFAAVMNNG 190 200 210 220 230 240 HRAAGRGGVG AVMGSKNLKA IVVRGHKRVE VADKGKFMEV IREKIEKLKK DPVAGGGLPK 250 260 270 280 290 300 YGTAVLVNII NEHGLYPTRN FQTGVFEYAY EQSGEAMAAK YLIRNKPCFA CPIGCGRVNY 310 320 330 340 350 360 LPSIGETEGP EYESTWALGA NLGINDLASI IEANHFADEY GMDTISLGGT LATAMELYER 370 380 390 400 410 420 GLIKQEDIGG ENEPPFRFGN TEVLHYWIHK IAKREGFGDI LAEGGYRLAE RFNGTEYFMG 430 440 450 460 470 480 VKKQELPAYD PRGAEGHGLG YATNNRGGCH IKQYMISPEI LGYPYKMDPH DISDEKVKMV 490 500 510 520 530 540 ILFQDLTALI DAAGLCLFTT FGLGADDYRD MLNAALGWDF STEDYLKIGE RIWNAERLFN 550 560 570 580 590 600 LKAGLDPLKE DTLPKRLLEE PMPEGPNKGH VVRLKEMLPR YYKLRGWTED GRIPEEKLKE LGLEEFI

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ248286 Genomic DNA. Translation: CAB49871.1.
PIR	B75071.
RefSeq	NP_126640.1.
3D structure databases
HSSP	HSSP built from PDB template 1AOR based on UniProtKB Q51739.
SMR	Q9V035. Positions 1-606.
ModBase	Search...
Genome annotation databases
GeneID	1496313.
GenomeReviews	Gene locus PYRAB09630 in contig AL096836_GR.
KEGG	pab:PAB0647.
NMPDR	fig|272844.1.peg.1006.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9V035.
OMA	Q9V035. CTIACGR.
Enzyme and pathway databases
BioCyc	PABY272844:PAB0647-MON.
BRENDA	1.2.7.5. 262861.
Family and domain databases
InterPro	IPR013985. Ald_Fedxn_OxRdtase_3. IPR013983. Ald_Fedxn_OxRdtase_N. IPR001203. OxRdtase_Ald_Fedxn_C. [Graphical view]
Gene3D	G3DSA:1.10.599.10. Oxred_Ald_Fedxn_3. 1 hit. G3DSA:3.60.9.10. Oxred_Ald_Fedxn_N. 1 hit.
Pfam	PF01314. AFOR_C. 1 hit. PF02730. AFOR_N. 1 hit. [Graphical view]
SMART	SM00790. AFOR_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AOR_PYRAB

Accession

Primary (citable) accession number: Q9V035

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 14, 2001
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)