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Protein

TATA-box-binding protein

Gene

tbp

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein
Alternative name(s):
Box A-binding protein
Short name:
BAP
TATA sequence-binding protein
Short name:
TBP
TATA-box factor
Gene namesi
Name:tbp
Ordered Locus Names:PYRAB09740
ORF Names:PAB1726
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 191191TATA-box-binding proteinPRO_0000154017Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB1726.

Structurei

3D structure databases

ProteinModelPortaliQ9V024.
SMRiQ9V024. Positions 2-184.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati11 – 87771Add
BLAST
Repeati102 – 178772Add
BLAST

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiMDCLEAI.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9V024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDTNNVKLR IENIVASVDL FAQLDLEKVL DICPNSKYNP EEFPGIICRF
60 70 80 90 100
DDPKVALLIF SSGKLVVTGA KSIHDIERAV AKLIEKLKGI GVKFKRAPLI
110 120 130 140 150
DIQNMVFSGD IGREFNLDNV ALTLPNCEYE PEQFPGVIYR VKDPRAVILL
160 170 180 190
FSSGKIVCSG AKSEADAWEA VRKLLRELEK YGLIEEEEEE L
Length:191
Mass (Da):21,410
Last modified:May 1, 2000 - v1
Checksum:iB997B5ED96F8DCB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248286 Genomic DNA. Translation: CAB49882.1.
HE613800 Genomic DNA. Translation: CCE70380.1.
PIRiE75072.
RefSeqiWP_010868091.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB49882; CAB49882; PAB1726.
GeneIDi1496324.
KEGGipab:PAB1726.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248286 Genomic DNA. Translation: CAB49882.1.
HE613800 Genomic DNA. Translation: CCE70380.1.
PIRiE75072.
RefSeqiWP_010868091.1. NC_000868.1.

3D structure databases

ProteinModelPortaliQ9V024.
SMRiQ9V024. Positions 2-184.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272844.PAB1726.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB49882; CAB49882; PAB1726.
GeneIDi1496324.
KEGGipab:PAB1726.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiMDCLEAI.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / Orsay.
  2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
    Gao J., Wang J.
    Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GE5 / Orsay.

Entry informationi

Entry nameiTBP_PYRAB
AccessioniPrimary (citable) accession number: Q9V024
Secondary accession number(s): G8ZID9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: November 11, 2015
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.