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Q9UZW0

- PGK_PYRAB

UniProt

Q9UZW0 - PGK_PYRAB

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Protein
Phosphoglycerate kinase
Gene
pgk, PYRAB10360, PAB1679
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei34 – 341Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei154 – 1541Substrate By similarity
Binding sitei332 – 3321ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi358 – 3614ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:PYRAB10360
ORF Names:PAB1679
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000810: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 410410Phosphoglycerate kinaseUniRule annotation
PRO_0000146064Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272844.PAB1679.

Structurei

3D structure databases

ProteinModelPortaliQ9UZW0.
SMRiQ9UZW0. Positions 1-405.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 213Substrate binding By similarity
Regioni57 – 604Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UZW0-1 [UniParc]FASTAAdd to Basket

« Hide

MFRLGDFNYH NKVVFLRVDL NSPMKDGKII SDARFRAVLP TIKYLLENGA    50
RVVVGTHQGK PYSEDYATTE EHARILSNLL NQHVEYVEDI FGRYAREKIQ 100
ELKPGEIAML ENLRFSAEEV KNKPIEECEK TFFVKKLSKV IDYVVNDAFA 150
AAHRSQPSLV GFARIKPMIM GFLMEREIEA LMKAYYSKES PRVYVLGGAK 200
VDDSLKVAEN VLRRGFADVI LTGGLVANVF TLAKGFDLGR KNIEFMKKKG 250
LLELVKHAEK ILDEFYPYVR TPVDFAIDYK GDREEIYLLS EKRELLNDYQ 300
IMDIGSRTIE KYRDIIMKAK VVVANGPMGV FEREEFALGT VEVFKAIAES 350
EAFSVLGGGH SIASIQKYGI EGITHISTGG GAMLTFFAGE ELPVLRALQI 400
SYEKFKEVKA 410
Length:410
Mass (Da):46,373
Last modified:May 1, 2000 - v1
Checksum:iA298DFDD0EDD5DC5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ248286 Genomic DNA. Translation: CAB49946.1.
HE613800 Genomic DNA. Translation: CCE70445.1.
PIRiE75080.
RefSeqiNP_126715.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB49946; CAB49946; PAB1679.
GeneIDi1496390.
KEGGipab:PAB1679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ248286 Genomic DNA. Translation: CAB49946.1 .
HE613800 Genomic DNA. Translation: CCE70445.1 .
PIRi E75080.
RefSeqi NP_126715.1. NC_000868.1.

3D structure databases

ProteinModelPortali Q9UZW0.
SMRi Q9UZW0. Positions 1-405.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272844.PAB1679.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB49946 ; CAB49946 ; PAB1679 .
GeneIDi 1496390.
KEGGi pab:PAB1679.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / Orsay.
  2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
    Gao J., Wang J.
    Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GE5 / Orsay.

Entry informationi

Entry nameiPGK_PYRAB
AccessioniPrimary (citable) accession number: Q9UZW0
Secondary accession number(s): G8ZJI6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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