Q9UZV9 (Q9UZV9_PYRAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Asd aspartate-semialdehyde dehydrogenase EMBL CAB49947.1

Gene names

Ordered Locus Names:	PYRAB10370
ORF Names:	PAB1678 EMBL CAB49947.1

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP] EMBL CAB49947.1

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family. RuleBase RU004041

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	143	1	Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1

Sequences

	Sequence		Length	Mass (Da)
	Q9UZV9 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 4A26E57A921CDA99	FASTA	335	37,164
	10 20 30 40 50 60 MKRVAVLGAT GLVGRTFVKL LGGHPWFKVE KLIASEKSAG KKYGDLVEDS PEEFRDYYVI 70 80 90 100 110 120 SLNEFLENPG VDLVFNALPA SISRDVEEKL AQEIPVFTNA RAHRYDEDVP ILVPEVNKDH 130 140 150 160 170 180 LKLVEVQRKR RGWKGFIVTN PNCSTAILTL SLAPLRNFGI KKVRVATMQA ISGAGFSGLS 190 200 210 220 230 240 AYAIQDNVIP FISGEEWKIE NESKKIMGKL KGDEIEPASF DVIAIATRVP VIHGHTEAVF 250 260 270 280 290 300 VELENPDIKS IREAIENFDP LKDLKLPSYE KPIVYTEIPQ PRLHRDRGRG LTVTVGRLER 310 320 330 TSEGVKYVAL GHNLVRGAAG GSVLNAELAY KLKII

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248286 Genomic DNA. Translation: CAB49947.1.
PIR	F75080.
RefSeq	NP_126716.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9UZV9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002392; EBPYRP00000002323; EBPYRG00000002392.
GeneID	1496391.
GenomeReviews	Gene locus PYRAB10370 in contig AL096836_GR.
KEGG	pab:PAB1678.
NMPDR	fig|272844.1.peg.1084.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023157.
HOGENOM	HBG518238.
OMA	GAGYNGV.
PhylomeDB	Q9UZV9.
ProtClustDB	PRK08664.
Enzyme and pathway databases
BioCyc	PABY272844:PAB1678-MONOMER.
Family and domain databases
InterPro	IPR005676. Asp_semi-ald_DH_pep-lack. IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00133.
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00978. Asd_EA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9UZV9_PYRAB

Accession

Primary (citable) accession number: Q9UZV9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)