Q9UZV6 (Q9UZV6_PYRAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartokinase RuleBase RU003448
EC=2.7.2.4 RuleBase RU003448

Gene names

Ordered Locus Names:	PYRAB10400
ORF Names:	PAB1675 EMBL CAB49950.1

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP] EMBL CAB49950.1

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate = ADP + 4-phospho-L-aspartate. RuleBase RU003448
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; tetrahydrodipicolinate from L-aspartate: step 1/4. RuleBase RU004249 Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3. RuleBase RU004249 Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5. RuleBase RU004249
Sequence similarities	Belongs to the aspartokinase family. RuleBase RU003448

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004249
Molecular function	Kinase RuleBase RU003448 EMBL CAB49950.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aspartate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9UZV6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 0B9B7624E9344EF4	FASTA	352	39,565
	10 20 30 40 50 60 MVYKLLVVKF GGSSVRYAFE EALELVKYLS ERIPIVVVVS ALKGVTDELI RFANGDKGAL 70 80 90 100 110 120 PRIERIHEEF LNYHGLNTKI SISFRKDMPP EALRDEIISL GERISAKIFA EGLELLGIKS 130 140 150 160 170 180 KVVDPLEFLI AKGEFGDAYI NIQESKRRAG KLIRLIKSGV IPVIPGFYGN LNGFRVTFGR 190 200 210 220 230 240 GGSDYSATAL ARILDSRCVL IMSDVEGIFT ADPKLVPSAR LIPYLSYEEI KVAAKLGMKA 250 260 270 280 290 300 LHWKAVDPVV GDIPIIFGKT KDWKFGTIVL NARSNFPIIV HRVREDFAEI FVVGRNISLP 310 320 330 340 350 GFLVEEERED FVKIVVARED LPEAIREIHR EVVEREEKNL RTGNNSELWA RI

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248286 Genomic DNA. Translation: CAB49950.1.
PIR	A75081.
RefSeq	NP_126719.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9UZV6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002458; EBPYRP00000002389; EBPYRG00000002458.
GeneID	1496394.
GenomeReviews	Gene locus PYRAB10400 in contig AL096836_GR.
KEGG	pab:PAB1675.
NMPDR	fig|272844.1.peg.1087.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022263.
HOGENOM	HBG645244.
OMA	GNLNGFR.
PhylomeDB	Q9UZV6.
ProtClustDB	PRK08373.
Enzyme and pathway databases
BioCyc	PABY272844:PAB1675-MONOMER.
Family and domain databases
InterPro	IPR001048. Asp/Glu/Uridylate_kinase. IPR018042. Aspartate_kinase_CS. IPR011819. AspKin_pair. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 2 hits.
KO	K00928.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR02078. AspKin_pair. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UZV6_PYRAB

Accession

Primary (citable) accession number: Q9UZV6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)