Reviewed, UniProtKB/Swiss-Prot Q9UZC1 (MPGS_PYRAB)

Names and origin

Protein names

Recommended name:
    Mannosyl-3-phosphoglycerate synthase
      Short name=MPG synthase
      Short name=MPGS
    EC=2.4.1.217

Gene names

Name:	mngA
Ordered Locus Names:	PYRAB12270
ORF Names:	PAB0816

Organism

Pyrococcus abyssi [Complete proteome] [HAMAP]

Taxonomic identifier

29292 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG) By similarity.
Catalytic activity	GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate.
Pathway	Carbohydrate biosynthesis; mannosylglycerate biosynthesis; 2(alpha-D-mannosyl)-D-glycerate from GDP-D-mannose (MPG route): step 1/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glycosyltransferase 2 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mannosylglycerate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	mannosyl-3-phosphoglycerate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannosyl-3-phosphoglycerate synthase		PRO_0000059285

Sequences

	Sequence		Length	Mass (Da)
	Q9UZC1-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 298B760B56B9145D	FASTA	394	45,288
	10 20 30 40 50 60 MLLEAPVYKE IFGAVTIHEV QKVIKMDTET EDVPVYTISN IPREKIYNLL GKMAIIVPMK 70 80 90 100 110 120 NEKLHLVDGV LKAIPHKCPI IIVSNSKREG PNRYKLEVDL VRHFYNLTHS KVIMIHQKDP 130 140 150 160 170 180 GLAKAFKEVG YTDILDGKGK VRSGKGEGMI IGMLLAKAIG AEYIGFVDAD NYIPGSVNEY 190 200 210 220 230 240 VKDYAAGFLM SESDYTMVRL HWRHKPKVTK GTLYFKKWGR VSEITNHYLN LLISEHTAFE 250 260 270 280 290 300 TTIMVTGNAG EHAMTMKLAE IMPFSTGYSV EPYEIVYLLE RFGKWENVDE FKEVFDQGIE 310 320 330 340 350 360 IFQIETLNPH FHEDKGQEHV KEMLLLSLAT IYHSKLATNS LKKKILNDLR EHKILKENEE 370 380 390 PPKPLVMRPI KEIPIKEWME IVEDNSETLL RFEL

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ248286 Genomic DNA. Translation: CAB50138.1.
PIR	E75104.
RefSeq	NP_126908.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT55. Glycosyltransferase Family 55.
Genome annotation databases
GeneID	1496614.
GenomeReviews	Gene locus PYRAB12270 in contig AL096836_GR.
KEGG	pab:PAB0816.
NMPDR	fig|272844.1.peg.1307.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9UZC1.
OMA	Q9UZC1. EIFQIET.
Enzyme and pathway databases
BioCyc	PABY272844:PAB0816-MON.
BRENDA	2.4.1.217. 262861.
Family and domain databases
InterPro	IPR012812. Osmo_MPG_synth. [Graphical view]
Pfam	PF09488. Osmo_MPGsynth. 1 hit. [Graphical view]
TIGRFAMs	TIGR02460. osmo_MPGsynth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGS_PYRAB

Accession

Primary (citable) accession number: Q9UZC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)