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Q9UZC1 (MPGS_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannosyl-3-phosphoglycerate synthase
Short name=MPG synthase
Short name=MPGS
EC=2.4.1.217
Gene names
Name:mngA
Ordered Locus Names:PYRAB12270
ORF Names:PAB0816
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG) By similarity.

Catalytic activity

GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate.

Pathway

Carbohydrate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route): step 1/2.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glycosyltransferase 2 family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmannosylglycerate biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmannosyl-3-phosphoglycerate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Mannosyl-3-phosphoglycerate synthase
PRO_0000059285

Sequences

Sequence LengthMass (Da)Tools
Q9UZC1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 298B760B56B9145D

FASTA39445,288
        10         20         30         40         50         60 
MLLEAPVYKE IFGAVTIHEV QKVIKMDTET EDVPVYTISN IPREKIYNLL GKMAIIVPMK 

        70         80         90        100        110        120 
NEKLHLVDGV LKAIPHKCPI IIVSNSKREG PNRYKLEVDL VRHFYNLTHS KVIMIHQKDP 

       130        140        150        160        170        180 
GLAKAFKEVG YTDILDGKGK VRSGKGEGMI IGMLLAKAIG AEYIGFVDAD NYIPGSVNEY 

       190        200        210        220        230        240 
VKDYAAGFLM SESDYTMVRL HWRHKPKVTK GTLYFKKWGR VSEITNHYLN LLISEHTAFE 

       250        260        270        280        290        300 
TTIMVTGNAG EHAMTMKLAE IMPFSTGYSV EPYEIVYLLE RFGKWENVDE FKEVFDQGIE 

       310        320        330        340        350        360 
IFQIETLNPH FHEDKGQEHV KEMLLLSLAT IYHSKLATNS LKKKILNDLR EHKILKENEE 

       370        380        390 
PPKPLVMRPI KEIPIKEWME IVEDNSETLL RFEL

« Hide

References

[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ248286 Genomic DNA. Translation: CAB50138.1.
PIRE75104.
RefSeqNP_126908.1. NC_000868.1.

3D structure databases

ModBaseSearch...

Protein family/group databases

CAZyGT55. Glycosyltransferase Family 55.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000002192; EBPYRP00000002123; EBPYRG00000002192.
GeneID1496614.
GenomeReviewsGene locus PYRAB12270 in contig AL096836_GR.
KEGGpab:PAB0816.
NMPDRfig|272844.1.peg.1307.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000022714.
HOGENOMHBG297698.
OMARVSEITN.
ProtClustDBPRK14503.

Enzyme and pathway databases

BioCycPABY272844:PAB0816-MONOMER.

Family and domain databases

InterProIPR012812. Osmo_MPG_synth.
[Graphical view]
KOK05947.
PfamPF09488. Osmo_MPGsynth. 1 hit.
[Graphical view]
TIGRFAMsTIGR02460. Osmo_MPGsynth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMPGS_PYRAB
AccessionPrimary (citable) accession number: Q9UZC1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 12, 2003
Last sequence update: May 1, 2000
Last modified: November 16, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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