Q9UZC0 (MPGP_PYRAB) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Mannosyl-3-phosphoglycerate phosphatase Short name=MPGP EC=3.1.3.70 | ||||||
| Gene names |
| ||||||
| Organism | Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 272844 [NCBI] | ||||||
| Taxonomic lineage | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus |
Protein attributes
| Sequence length | 243 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) By similarity. HAMAP MF_00617 |
| Catalytic activity | 2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. HAMAP MF_00617 |
| Pathway | Carbohydrate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route): step 2/2. HAMAP MF_00617 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00617. |
| Sequence similarities | Belongs to the HAD-like hydrolase superfamily. MPGP family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | mannosylglycerate biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | mannosyl-3-phosphoglycerate phosphatase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 243 | 243 | Mannosyl-3-phosphoglycerate phosphatase HAMAP MF_00617 | PRO_0000184971 | |||
Sequences
| ||||||||||||||||||
References
| [1] | "An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AJ248286 Genomic DNA. Translation: CAB50139.1. |
| PIR | F75104. |
| RefSeq | NP_126909.1. NC_000868.1. |
3D structure databases | |
| ProteinModelPortal | Q9UZC0. |
| SMR | Q9UZC0. Positions 1-243. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBPYRT00000003598; EBPYRP00000003529; EBPYRG00000003598. |
| GeneID | 1496615. |
| GenomeReviews | Gene locus PYRAB12280 in contig AL096836_GR. |
| KEGG | pab:PAB0817. |
| NMPDR | fig|272844.1.peg.1308. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000023295. |
| HOGENOM | HBG635303. |
| OMA | EYSETIF. |
| PhylomeDB | Q9UZC0. |
| ProtClustDB | PRK00192. |
Enzyme and pathway databases | |
| BioCyc | PABY272844:PAB0817-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00617. MPGP_rel. [Tree] |
| InterPro | IPR023214. HAD-like_dom. IPR013200. HAD-SF_hydro-like_3. IPR006379. HAD-SF_hydro_IIB. IPR006381. HAD-SF_hydro_IIB_YedP. IPR012815. MPG_Pase. IPR012813. Osmo_MPG_phos. [Graphical view] |
| Gene3D | G3DSA:3.40.50.1000. HAD-like_dom. 2 hits. |
| KO | K07026. |
| Pfam | PF08282. Hydrolase_3. 1 hit. [Graphical view] |
| SUPFAM | SSF56784. HAD-like_dom. 1 hit. |
| TIGRFAMs | TIGR01484. HAD-SF-IIB. 1 hit. TIGR01486. HAD-SF-IIB-MPGP. 1 hit. TIGR02461. Osmo_MPG_phos. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MPGP_PYRAB | ||||||||
| Accession | Primary (citable) accession number: Q9UZC0 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with