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Protein
Submitted name:

ABC transporter ATP-binding protein

Gene

PAB0824

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi15 – 151Iron-sulfur (4Fe-4S) 1Combined sources
Metal bindingi20 – 201Iron-sulfur (4Fe-4S) 1Combined sources
Metal bindingi25 – 251Iron-sulfur (4Fe-4S) 1Combined sources
Metal bindingi29 – 291Iron-sulfur (4Fe-4S) 2Combined sources
Metal bindingi55 – 551Iron-sulfur (4Fe-4S) 2Combined sources
Metal bindingi58 – 581Iron-sulfur (4Fe-4S) 2Combined sources
Metal bindingi61 – 611Iron-sulfur (4Fe-4S) 2Combined sources
Metal bindingi65 – 651Iron-sulfur (4Fe-4S) 1Combined sources
Binding sitei87 – 871ADPCombined sources
Binding sitei92 – 921ADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi112 – 1187ADPCombined sources
Nucleotide bindingi353 – 3564ADPCombined sources
Nucleotide bindingi378 – 3836ADPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4SCombined sources, ATP-bindingUniRule annotationImported, Iron, Iron-sulfur, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ABC transporter ATP-binding proteinImported
Gene namesi
ORF Names:PAB0824Imported
OrganismiPyrococcus abyssi (strain GE5 / Orsay)Imported
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi83 ↔ 132Combined sources

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB0824.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BK7X-ray2.80A1-593[»]
ProteinModelPortaliQ9UZA4.
SMRiQ9UZA4. Positions 1-593.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9UZA4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 39344Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini46 – 75304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini70 – 313244ABC transporterInterPro annotationAdd
BLAST
Domaini338 – 558221ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transporter domains.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00187. Archaea.
COG1245. LUCA.
HOGENOMiHOG000222803.
KOiK06174.
OMAiAYKPQYI.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UZA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRKMRIAVI DYDKCNPDKC GHFLCERVCP VNRMGGEAII IDEENYKPII
60 70 80 90 100
QEASCTGCGI CVHKCPFNAI SIVNLPEQLD EDCVHRYGVN AFVLYRLPIV
110 120 130 140 150
KDGMVVGIVG PNGTGKTTAV KILAGQLIPN LCEDNDSWDN VIRAFRGNEL
160 170 180 190 200
QNYFERLKNG EIRPVVKPQY VDLLPKAVKG KVRELLKKVD EVGKFEEVVK
210 220 230 240 250
ELELENVLDR ELHQLSGGEL QRVAIAAALL RKAHFYFFDE PSSYLDIRQR
260 270 280 290 300
LKVARVIRRL ANEGKAVLVV EHDLAVLDYL SDVIHVVYGE PGVYGIFSKP
310 320 330 340 350
KGTRNGINEF LQGYLKDENV RFRPYEIRFT KLSERVDVER ETLVEYPRLV
360 370 380 390 400
KDYGSFKLEV EPGEIRKGEV IGIVGPNGIG KTTFVKMLAG VEEPTEGKVE
410 420 430 440 450
WDLTVAYKPQ YIKAEYEGTV YELLSKIDSS KLNSNFYKTE LLKPLGIIDL
460 470 480 490 500
YDRNVEDLSG GELQRVAIAA TLLRDADIYL LDEPSAYLDV EQRLAVSRAI
510 520 530 540 550
RHLMEKNEKT ALVVEHDVLM IDYVSDRLIV FEGEPGRHGR ALPPMGMREG
560 570 580 590
MNRFLASVGI TFRRDPDSGR PRANKEGSVK DREQKARGEY YYA
Length:593
Mass (Da):67,191
Last modified:May 1, 2000 - v1
Checksum:i2CFC43FDA5D42F93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248287 Genomic DNA. Translation: CAB50155.1.
PIRiF75032.

Genome annotation databases

EnsemblBacteriaiCAB50155; CAB50155; PAB0824.
KEGGipab:PAB0824.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248287 Genomic DNA. Translation: CAB50155.1.
PIRiF75032.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BK7X-ray2.80A1-593[»]
ProteinModelPortaliQ9UZA4.
SMRiQ9UZA4. Positions 1-593.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272844.PAB0824.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB50155; CAB50155; PAB0824.
KEGGipab:PAB0824.

Phylogenomic databases

eggNOGiarCOG00187. Archaea.
COG1245. LUCA.
HOGENOMiHOG000222803.
KOiK06174.
OMAiAYKPQYI.

Miscellaneous databases

EvolutionaryTraceiQ9UZA4.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / OrsayImported.
  2. "X-ray structure of the complete ABC enzyme ABCE1 from Pyrococcus abyssi."
    Karcher A., Schele A., Hopfner K.P.
    J. Biol. Chem. 283:7962-7971(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH ADP AND IRON-SULFUR (4FE-4S), DISULFIDE BONDS.

Entry informationi

Entry nameiQ9UZA4_PYRAB
AccessioniPrimary (citable) accession number: Q9UZA4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 13, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.