Reviewed, UniProtKB/Swiss-Prot Q9UYZ5 (PORB_PYRAB)

Names and origin

Protein names

Recommended name:
    Pyruvate synthase subunit porB
    EC=1.2.7.1
Alternative name(s):
    Pyruvate oxidoreductase beta chain
      Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit beta

Gene names

Name:	porB
Ordered Locus Names:	PYRAB13620
ORF Names:	PAB1476

Organism

Pyrococcus abyssi [Complete proteome] [HAMAP]

Taxonomic identifier

29292 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	pyruvate synthase activity Inferred from electronic annotation. Source: EC thiamin pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 331	330	Pyruvate synthase subunit porB		PRO_0000099906

Sequences

	Sequence		Length	Mass (Da)
	Q9UYZ5-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 6128CDB760D64740	FASTA	331	36,196
	10 20 30 40 50 60 MAVRKPPITT REYWAPGHAA CAGCGCATAL RLATKAFSEA MEEKYGDPNA FAIAQATGCM 70 80 90 100 110 120 EVVSAVFPYT AWKVPWVHVA FENAAAAASG IEAAWKKKGI KGKILAIGGD GGTADIGLQA 130 140 150 160 170 180 LSGMLERGHN VVYLMYDNEA YMNTGIQRSS STPYGAWTTT SPPGKYSIGE DRPKKWVALI 190 200 210 220 230 240 AAAHMIPYVA TASIGNPFDF VKKVKKAAKV DGPAFVQVHC TCPTGWRTPL EKGIEIARLA 250 260 270 280 290 300 IETGMWPLFE IENGDIWHIK IQPPGGGAKV YKEGGRVVRI EFKKPIEEYL KYQGRFKHLF 310 320 330 KRPEAIDELR NQIKAMWKVL GVEAILPKPE E

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ248287 Genomic DNA. Translation: CAB50267.1. Different initiation.
PIR	F75046.
RefSeq	NP_127037.1.
3D structure databases
HSSP	HSSP built from PDB template 1KEK based on UniProtKB P94692.
ModBase	Search...
Genome annotation databases
GeneID	1496751.
GenomeReviews	Gene locus PYRAB13620 in contig AL096836_GR.
KEGG	pab:PAB1476.
NMPDR	fig|272844.1.peg.1444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9UYZ5.
OMA	Q9UYZ5. YICLDNE.
Enzyme and pathway databases
BioCyc	PABY272844:PAB1476-MON.
BRENDA	1.2.7.1. 262861.
Family and domain databases
InterPro	IPR011766. TPP_enzyme_bd_C. [Graphical view]
Pfam	PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PORB_PYRAB

Accession

Primary (citable) accession number: Q9UYZ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 48 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)