Reviewed, UniProtKB/Swiss-Prot Q9UYZ4 (PORA_PYRAB)

Names and origin

Protein names

Recommended name:
    Pyruvate synthase subunit porA
    EC=1.2.7.1
Alternative name(s):
    Pyruvate oxidoreductase alpha chain
      Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit alpha

Gene names

Name:	porA
Ordered Locus Names:	PYRAB13630
ORF Names:	PAB1475

Organism

Pyrococcus abyssi [Complete proteome] [HAMAP]

Taxonomic identifier

29292 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro pyruvate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 395	395	Pyruvate synthase subunit porA		PRO_0000099899

Sequences

	Sequence		Length	Mass (Da)
	Q9UYZ4-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: E8E09713008A8083	FASTA	395	44,045
	10 20 30 40 50 60 MPIRTVMKAN EAAAWAAKLA KPKVIAAFPI TPSTLVPEKI SEFVANGELD AEFIKVESEH 70 80 90 100 110 120 SAISALVGAS AAGVRTFTAT ASQGLALMHE VLFIAAGMRL PIVMAIGNRA LSAPINIWND 130 140 150 160 170 180 WQDTISQRDT GWIQFYAENN QEALDLILLA YKVAEDERVL LPAMVGFDAF ILTHTVEPVE 190 200 210 220 230 240 IPDQEVVDEF LGEYEPKHAY LDPKRPITQG TLAFPAHYME ARYLVWEAME NARKVIDEAF 250 260 270 280 290 300 AEFEKKFGRK YQKIEEYRTD DAEIIFVTMG SLAGTLKDWV DKKREEGYKV GAAKMTVYRP 310 320 330 340 350 360 FPVEEIRELA KKTKVLAFIE KDISMGLYGA VFTDASAALI NESEKPLMLD FIAGLGGRDV 370 380 390 TFNQLDEALS IAKEALEKGK VEKPIHWIGL RKELL

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ248287 Genomic DNA. Translation: CAB50268.1.
PIR	G75046.
RefSeq	NP_127038.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1496752.
GenomeReviews	Gene locus PYRAB13630 in contig AL096836_GR.
KEGG	pab:PAB1475.
NMPDR	fig|272844.1.peg.1445.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9UYZ4.
OMA	Q9UYZ4. LYQASGM.
Enzyme and pathway databases
BioCyc	PABY272844:PAB1475-MON.
BRENDA	1.2.7.1. 262861.
Family and domain databases
InterPro	IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N. IPR015941. Transketolase_C-like. [Graphical view]
Gene3D	G3DSA:3.40.50.920. Transketo_C_like. 1 hit.
Pfam	PF01855. POR_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PORA_PYRAB

Accession

Primary (citable) accession number: Q9UYZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	May 1, 2000
Last modified:	May 5, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)