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Q9UYY9 (PORC_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma

Including the following 2 domains:

  1. Pyruvate synthase subunit porC
    EC=1.2.7.1
    Alternative name(s):
    Pyruvate oxidoreductase gamma chain
    Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit gamma
  2. Ketoisovalerate oxidoreductase subunit vorC
    Short name=VOR
    EC=1.2.7.7
    Alternative name(s):
    2-oxoisovalerate ferredoxin reductase subunit gamma
    2-oxoisovalerate oxidoreductase gamma chain
Gene names
Name:porG
Ordered Locus Names:PYRAB13680
ORF Names:PAB1470
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.

Subunit structure

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
PRO_0000099913

Sequences

Sequence LengthMass (Da)Tools
Q9UYY9 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 2387E6FE6C6A27EC

FASTA18520,023
        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAANI LAEAAFIEGK YVQAFPFFGV ERRGAPVTAF TRIDEKPIRI 

        70         80         90        100        110        120 
KTQIYEPDVV VVLDPSLLET VDVTAGLKED GIVIVNTEKS KEEVLEKLKR KPKKLALVDA 

       130        140        150        160        170        180 
TTIALETLGL PITNTAILGA VAKATGLVKI ESVETAIKDT FSGELGEKNA KAAREAFEKT 


QIFEV 

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References

[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ248287 Genomic DNA. Translation: CAB50273.1.
PIRD75047.
RefSeqNP_127043.1. NC_000868.1.

3D structure databases

ProteinModelPortalQ9UYY9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000002565; EBPYRP00000002496; EBPYRG00000002565.
GeneID1496757.
GenomeReviewsGene locus PYRAB13680 in contig AL096836_GR.
KEGGpab:PAB1470.
NMPDRfig|272844.1.peg.1450.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000022250.
HOGENOMHBG553299.
OMADYVIVQD.
ProtClustDBPRK14029.

Enzyme and pathway databases

BioCycPABY272844:PAB1470-MONOMER.

Family and domain databases

InterProIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
Gene3DG3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
KOK00189.
PfamPF01558. POR. 1 hit.
[Graphical view]
SUPFAMSSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMsTIGR02175. PorC_KorC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePORC_PYRAB
AccessionPrimary (citable) accession number: Q9UYY9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 2000
Last modified: November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program