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Protein

Translation initiation factor 6

Gene

eif6

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciPABY272844:G1GT8-1677-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 6UniRule annotation
Short name:
aIF-6UniRule annotation
Gene namesi
Name:eif6UniRule annotation
Ordered Locus Names:PYRAB15210
ORF Names:PAB1005
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001537531 – 227Translation initiation factor 6Add BLAST227

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB1005

Structurei

3D structure databases

ProteinModelPortaliQ9UYI6
SMRiQ9UYI6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04176 Archaea
COG1976 LUCA
HOGENOMiHOG000230604
KOiK03264
OMAiNDWCAFT
OrthoDBiPOG093Z0C2O

Family and domain databases

CDDicd00527 IF6, 1 hit
HAMAPiMF_00032 eIF_6, 1 hit
InterProiView protein in InterPro
IPR002769 eIF6
PANTHERiPTHR10784 PTHR10784, 1 hit
PfamiView protein in Pfam
PF01912 eIF-6, 1 hit
PIRSFiPIRSF006413 IF-6, 1 hit
SMARTiView protein in SMART
SM00654 eIF6, 1 hit
TIGRFAMsiTIGR00323 eIF-6, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UYI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIERLDFEN SPYLGVFGVA TDRVVLVREG LQEKKLEVIR EVLKVPVIEA
60 70 80 90 100
SIMKSRIIGT LATGNSNAIL VPWYVWDTEI ERIKSAFKEY GIETEIVPFR
110 120 130 140 150
TKYTALGNLI LTNDKAALVS AKFSRDEAKE IGDILGVEVE RGLIAGLHAV
160 170 180 190 200
GSAGVVTNKG GLVHPEASDE ELEWLSELFK VDVYVGTANM GVPYVGTCML
210 220
ANSNGVVVGH LTTGPEIVKI EEALGLI
Length:227
Mass (Da):24,693
Last modified:May 1, 2000 - v1
Checksum:i1C8F1D8C960F54FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248287 Genomic DNA Translation: CAB50426.1
HE613800 Genomic DNA Translation: CCE70975.1
PIRiE75066
RefSeqiWP_010868639.1, NC_000868.1

Genome annotation databases

EnsemblBacteriaiCAB50426; CAB50426; PAB1005
GeneIDi1495804
KEGGipab:PAB1005
PATRICifig|272844.11.peg.1620

Similar proteinsi

Entry informationi

Entry nameiIF6_PYRAB
AccessioniPrimary (citable) accession number: Q9UYI6
Secondary accession number(s): G8ZIU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health