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Protein

Translation initiation factor 6

Gene

eif6

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

GO - Molecular functioni

  1. ribosome binding Source: InterPro
  2. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. mature ribosome assembly Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 6UniRule annotation
Short name:
aIF-6UniRule annotation
Gene namesi
Name:eif6UniRule annotation
Ordered Locus Names:PYRAB15210
ORF Names:PAB1005
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000810 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227Translation initiation factor 6PRO_0000153753Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB1005.

Structurei

3D structure databases

ProteinModelPortaliQ9UYI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1976.
HOGENOMiHOG000230604.
KOiK03264.
OMAiNDWCAFT.

Family and domain databases

HAMAPiMF_00032. eIF_6.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UYI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIERLDFEN SPYLGVFGVA TDRVVLVREG LQEKKLEVIR EVLKVPVIEA
60 70 80 90 100
SIMKSRIIGT LATGNSNAIL VPWYVWDTEI ERIKSAFKEY GIETEIVPFR
110 120 130 140 150
TKYTALGNLI LTNDKAALVS AKFSRDEAKE IGDILGVEVE RGLIAGLHAV
160 170 180 190 200
GSAGVVTNKG GLVHPEASDE ELEWLSELFK VDVYVGTANM GVPYVGTCML
210 220
ANSNGVVVGH LTTGPEIVKI EEALGLI
Length:227
Mass (Da):24,693
Last modified:May 1, 2000 - v1
Checksum:i1C8F1D8C960F54FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248287 Genomic DNA. Translation: CAB50426.1.
HE613800 Genomic DNA. Translation: CCE70975.1.
PIRiE75066.
RefSeqiNP_127196.1. NC_000868.1.
WP_010868639.1. NC_000868.1.

Genome annotation databases

GeneIDi1495804.
KEGGipab:PAB1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248287 Genomic DNA. Translation: CAB50426.1.
HE613800 Genomic DNA. Translation: CCE70975.1.
PIRiE75066.
RefSeqiNP_127196.1. NC_000868.1.
WP_010868639.1. NC_000868.1.

3D structure databases

ProteinModelPortaliQ9UYI6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272844.PAB1005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1495804.
KEGGipab:PAB1005.

Phylogenomic databases

eggNOGiCOG1976.
HOGENOMiHOG000230604.
KOiK03264.
OMAiNDWCAFT.

Family and domain databases

HAMAPiMF_00032. eIF_6.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / Orsay.
  2. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
    Gao J., Wang J.
    Curr. Microbiol. 64:118-129(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GE5 / Orsay.

Entry informationi

Entry nameiIF6_PYRAB
AccessioniPrimary (citable) accession number: Q9UYI6
Secondary accession number(s): G8ZIU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: April 1, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.