Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9UYI6 (IF6_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 6

Short name=aIF-6
Gene names
Name:eif6
Ordered Locus Names:PYRAB15210
ORF Names:PAB1005
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex By similarity. HAMAP-Rule MF_00032

Sequence similarities

Belongs to the eIF-6 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmature ribosome assembly

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribosome binding

Inferred from electronic annotation. Source: InterPro

translation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 227227Translation initiation factor 6 HAMAP-Rule MF_00032
PRO_0000153753

Sequences

Sequence LengthMass (Da)Tools
Q9UYI6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 1C8F1D8C960F54FE

FASTA22724,693
        10         20         30         40         50         60 
MHIERLDFEN SPYLGVFGVA TDRVVLVREG LQEKKLEVIR EVLKVPVIEA SIMKSRIIGT 

        70         80         90        100        110        120 
LATGNSNAIL VPWYVWDTEI ERIKSAFKEY GIETEIVPFR TKYTALGNLI LTNDKAALVS 

       130        140        150        160        170        180 
AKFSRDEAKE IGDILGVEVE RGLIAGLHAV GSAGVVTNKG GLVHPEASDE ELEWLSELFK 

       190        200        210        220 
VDVYVGTANM GVPYVGTCML ANSNGVVVGH LTTGPEIVKI EEALGLI 

« Hide

References

« Hide 'large scale' references
[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.
[2]"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
Gao J., Wang J.
Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ248287 Genomic DNA. Translation: CAB50426.1.
HE613800 Genomic DNA. Translation: CCE70975.1.
PIRE75066.
RefSeqNP_127196.1. NC_000868.1.

3D structure databases

ProteinModelPortalQ9UYI6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272844.PAB1005.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB50426; CAB50426; PAB1005.
GeneID1495804.
KEGGpab:PAB1005.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1976.
HOGENOMHOG000230604.
KOK03264.
OMANDWCAFT.
ProtClustDBPRK04046.

Family and domain databases

HAMAPMF_00032. eIF_6.
InterProIPR002769. eIF6.
[Graphical view]
PANTHERPTHR10784. PTHR10784. 1 hit.
PfamPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFPIRSF006413. IF-6. 1 hit.
SMARTSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsTIGR00323. eIF-6. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF6_PYRAB
AccessionPrimary (citable) accession number: Q9UYI6
Secondary accession number(s): G8ZIU2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries