Q9UYI6 (IF6_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor 6
Short name=aIF-6

Gene names

Name:	eif6
Ordered Locus Names:	PYRAB15210
ORF Names:	PAB1005

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus › Pyrococcus abyssi

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex By similarity. HAMAP-Rule MF_00032
Sequence similarities	Belongs to the eIF-6 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mature ribosome assembly Inferred from electronic annotation. Source: InterPro
Molecular_function	ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 227	227	Translation initiation factor 6 HAMAP-Rule MF_00032		PRO_0000153753

Sequences

	Sequence		Length	Mass (Da)
	Q9UYI6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 1C8F1D8C960F54FE	FASTA	227	24,693
	10 20 30 40 50 60 MHIERLDFEN SPYLGVFGVA TDRVVLVREG LQEKKLEVIR EVLKVPVIEA SIMKSRIIGT 70 80 90 100 110 120 LATGNSNAIL VPWYVWDTEI ERIKSAFKEY GIETEIVPFR TKYTALGNLI LTNDKAALVS 130 140 150 160 170 180 AKFSRDEAKE IGDILGVEVE RGLIAGLHAV GSAGVVTNKG GLVHPEASDE ELEWLSELFK 190 200 210 220 VDVYVGTANM GVPYVGTCML ANSNGVVVGH LTTGPEIVKI EEALGLI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.
[2]	"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638." Gao J., Wang J. Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248287 Genomic DNA. Translation: CAB50426.1. HE613800 Genomic DNA. Translation: CCE70975.1.
PIR	E75066.
RefSeq	NP_127196.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9UYI6.
ModBase	Search...
Protein-protein interaction databases
STRING	272844.PAB1005.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAB50426; CAB50426; PAB1005.
GeneID	1495804.
KEGG	pab:PAB1005.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1976.
HOGENOM	HOG000230604.
KO	K03264.
OMA	QFENSNE.
ProtClustDB	PRK04046.
Family and domain databases
HAMAP	MF_00032. eIF-6.
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. PTHR10784. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF6_PYRAB

Accession

Primary (citable) accession number: Q9UYI6
Secondary accession number(s): G8ZIU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program