Q9UY47 (ACYP_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	PYRAB16610
ORF Names:	PAB7421

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Acylphosphatase HAMAP MF_01450		PRO_0000158558
Regions
	Domain	5 – 91	87	Acylphosphatase-like
Sites
	Active site	20	1	By similarity
	Active site	38	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9UY47 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: A5265ACEB825D3AB	FASTA	91	10,323
	10 20 30 40 50 60 MGIVRAHLRI YGRVQGVGFR WSMQREARKL GVNGWVRNLP DGSVEAVLEG EEERVEALIG 70 80 90 WAHQGPPFAR VTRVEVKWEE PKGEKGFRIV G

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248288 Genomic DNA. Translation: CAB50565.1.
PIR	G75015.
RefSeq	NP_127335.1. NC_000868.1.
3D structure databases
ProteinModelPortal	Q9UY47.
SMR	Q9UY47. Positions 2-91.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002342; EBPYRP00000002273; EBPYRG00000002342.
GeneID	1495958.
GenomeReviews	Gene locus PYRAB16610 in contig AL096836_GR.
KEGG	pab:PAB7421.
NMPDR	fig|272844.1.peg.1768.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022948.
HOGENOM	HBG750266.
OMA	ALIGWAH.
PhylomeDB	Q9UY47.
ProtClustDB	PRK14436.
Enzyme and pathway databases
BioCyc	PABY272844:PAB7421-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_PYRAB

Accession

Primary (citable) accession number: Q9UY47

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program