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Q9UXX7 (RNP3_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 3

Short name=RNase P component 3
EC=3.1.26.5
Alternative name(s):
Rpp30
Gene names
Name:rnp3
Ordered Locus Names:PYRAB17310
ORF Names:PAB1136
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits Potential.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00756.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 212212Ribonuclease P protein component 3 HAMAP-Rule MF_00756
PRO_0000140044

Sequences

Sequence LengthMass (Da)Tools
Q9UXX7 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D170AE61916E5CA8

FASTA21224,365
        10         20         30         40         50         60 
MAGGGGLKFV EMDVRNDDAY KLAKEWFDEV VFSVKFQDSI DKELLREAER NYGLVAILLV 

        70         80         90        100        110        120 
NPRLSIVKEA VQRFKQNYLI YVESSDLRTI RYSIERGVDA IISPWVGRKD PGIDHTLARM 

       130        140        150        160        170        180 
MAKKGVALGF SLRPLLEASP YDKANILKFM RKAWQLTNKY KVKRFITSSA NEKWHIRWPR 

       190        200        210 
DLATLGIIIG MEVQQAKAAL STYPDIILKR LK 

« Hide

References

« Hide 'large scale' references
[1]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.
[2]"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
Gao J., Wang J.
Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ248288 Genomic DNA. Translation: CAB50636.1.
HE613800 Genomic DNA. Translation: CCE71204.1.
PIRF75024.
RefSeqNP_127407.1. NC_000868.1.

3D structure databases

ProteinModelPortalQ9UXX7.
SMRQ9UXX7. Positions 3-210.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272844.PAB1136.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB50636; CAB50636; PAB1136.
GeneID1496033.
KEGGpab:PAB1136.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1603.
HOGENOMHOG000073988.
KOK03539.
OMASSANEKW.

Family and domain databases

HAMAPMF_00756. RNase_P_3.
InterProIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERPTHR13031. PTHR13031. 1 hit.
PfamPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP3_PYRAB
AccessionPrimary (citable) accession number: Q9UXX7
Secondary accession number(s): G8ZK97
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families