Reviewed, UniProtKB/Swiss-Prot Q9UXX7 (RNP3_PYRAB)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 3
      Short name=RNase P component 3
    EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	PYRAB17310
ORF Names:	PAB1136

Organism

Pyrococcus abyssi [Complete proteome] [HAMAP]

Taxonomic identifier

29292 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_0000140044

Sequences

	Sequence		Length	Mass (Da)
	Q9UXX7-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: D170AE61916E5CA8	FASTA	212	24,365
	10 20 30 40 50 60 MAGGGGLKFV EMDVRNDDAY KLAKEWFDEV VFSVKFQDSI DKELLREAER NYGLVAILLV 70 80 90 100 110 120 NPRLSIVKEA VQRFKQNYLI YVESSDLRTI RYSIERGVDA IISPWVGRKD PGIDHTLARM 130 140 150 160 170 180 MAKKGVALGF SLRPLLEASP YDKANILKFM RKAWQLTNKY KVKRFITSSA NEKWHIRWPR 190 200 210 DLATLGIIIG MEVQQAKAAL STYPDIILKR LK

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ248288 Genomic DNA. Translation: CAB50636.1.
PIR	F75024.
RefSeq	NP_127407.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1496033.
GenomeReviews	Gene locus PYRAB17310 in contig AL096836_GR.
KEGG	pab:PAB1136.
NMPDR	fig|272844.1.peg.1843.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9UXX7.
OMA	YLIYVES.
Enzyme and pathway databases
BioCyc	PABY272844:PAB1136-MON.
BRENDA	3.1.26.5. 262861.
Family and domain databases
HAMAP	MF_00756. [Tree]
InterPro	IPR002738. RNase_P_p30. [Graphical view]
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
ProDom	PD016938. RNase_P_p30_arch. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RNP3_PYRAB

Accession

Primary (citable) accession number: Q9UXX7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	May 1, 2000
Last modified:	November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)