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Q9UXC4 (ECR1_SULSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable exosome complex RNA-binding protein 1
Gene names
Ordered Locus Names:SSO0736
ORF Names:C20_026
OrganismSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) [Reference proteome] [HAMAP]
Taxonomic identifier273057 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus ›

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome Potential. HAMAP-Rule MF_00623

Subunit structure

Component of the archaeal exosome multienzyme ribonuclease complex Potential.

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00623.

Sequence similarities

Contains 1 KH domain.

Contains 1 S1 motif domain.

Ontologies

Keywords
   Cellular componentCytoplasm
Exosome
   LigandRNA-binding
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processRNA catabolic process

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exosome (RNase complex)

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249Probable exosome complex RNA-binding protein 1 HAMAP-Rule MF_00623
PRO_0000050156

Regions

Domain73 – 14472S1 motif
Domain154 – 21158KH

Secondary structure

1 ................................................. 249
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9UXC4 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: A36AD0CA0363D4B8

FASTA24927,998
        10         20         30         40         50         60 
MNMSQSQKIV LQPRSIVVPG ELLAEGEFQI PWSPYILKIN SKYYSTVVGL FDVKDTQFEV 

        70         80         90        100        110        120 
IPLEGSFYYP KINDIVIGLV EDVEIYGWVV DIKAPYKAYL PASNLLGRSI NVGEDLRRYL 

       130        140        150        160        170        180 
DVGDYVIARI ENFDRSIDPV LSVKGKDLGR VSNGIVIDIM PVKVPRVIGK NKSMYETLTS 

       190        200        210        220        230        240 
KSGCSIFVAN NGRIWATCPS RFSEEILIEA IRKIENESHI KGLTDRIKQF IEEKLGERNA 


SSGETKTNS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Y18930 Genomic DNA. Translation: CAB57567.1.
AE006641 Genomic DNA. Translation: AAK41032.1.
PIRA99222.
RefSeqNP_342242.1. NC_002754.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2JE6X-ray1.60I1-249[»]
2JEAX-ray2.33I1-249[»]
2JEBX-ray2.40I1-249[»]
3L7ZX-ray2.41C/F/I1-249[»]
4BA1X-ray1.80I1-249[»]
4BA2X-ray2.50I1-249[»]
ProteinModelPortalQ9UXC4.
SMRQ9UXC4. Positions 7-221.
ModBaseSearch...

Protein-protein interaction databases

STRING273057.SSO0736.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK41032; AAK41032; SSO0736.
GeneID1454999.
KEGGsso:SSO0736.

Phylogenomic databases

eggNOGCOG1097.
HOGENOMHOG000229527.
KOK03679.
OMAVIPLEGP.
ProtClustDBPRK04163.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00623. Exosome_RNA-bind1.
InterProIPR023474. Exosome_RNA_bind1.
IPR026699. Exosome_RNA_bind1/RRP40/RRP4.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
[Graphical view]
PANTHERPTHR21321. PTHR21321. 1 hit.
PfamPF00013. KH_1. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
PROSITEPS50084. KH_TYPE_1. False negative.
PS50126. S1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9UXC4.

Entry information

Entry nameECR1_SULSO
AccessionPrimary (citable) accession number: Q9UXC4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: May 1, 2000
Last modified: May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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