Probable exosome complex exonuclease 1 - Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Contribute

Send feedback

Read comments (?) or add your own

Q9UXC2 (ECX1_SULSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 72. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Probable exosome complex exonuclease 1
EC=3.1.13.-

Gene names

Ordered Locus Names:

SSO0735

Organism

Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) [Reference proteome] [HAMAP]

Taxonomic identifier

273057 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus ›

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probably involved in the 3'->5' degradation of a variety of RNA species Potential. HAMAP-Rule MF_00591
Subunit structure	Component of the archaeal exosome multienzyme ribonuclease complex Potential.
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00591.
Sequence similarities	Belongs to the RNase PH family.

Ontologies

Keywords
Cellular component	Cytoplasm Exosome
Molecular function	Exonuclease Hydrolase Nuclease
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exosome (RNase complex) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	3'-5'-exoribonuclease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 248

248

Probable exosome complex exonuclease 1 HAMAP-Rule MF_00591

PRO_0000139991

Secondary structure

248

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

Q9UXC2 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: EAB2C2C89DD5854C
Show »

FASTA

248

27,578

        10         20         30         40         50         60 
MREMLQVERP KLILDDGKRT DGRKPDELRS IKIELGVLKN ADGSAIFEMG NTKAIAAVYG 

        70         80         90        100        110        120 
PKEMHPRHLS LPDRAVLRVR YHMTPFSTDE RKNPAPSRRE IELSKVIREA LESAVLVELF 

       130        140        150        160        170        180 
PRTAIDVFTE ILQADAGSRL VSLMAASLAL ADAGIPMRDL IAGVAVGKAD GVIILDLNET 

       190        200        210        220        230        240 
EDMWGEADMP IAMMPSLNQV TLFQLNGSMT PDEFRQAFDL AVKGINIIYN LEREALKSKY 


VEFKEEGV

« Hide

References

[1]	"Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2." Charlebois R.L., Singh R.K., Chan-Weiher C.C.-Y., Allard G., Chow C., Confalonieri F., Curtis B., Duguet M., Erauso G., Faguy D., Gaasterland T., Garrett R.A., Gordon P., Jeffries A.C., Kozera C., Kushwaha N., Lafleur E., Medina N. Sensen C.W. Genome 43:116-136(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
[2]	"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

Y18930 Genomic DNA. Translation: CAB57569.1.
AE006641 Genomic DNA. Translation: AAK41031.1.

PIR

H90221.

RefSeq

NP_342241.1. NC_002754.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2BR2	X-ray	2.80	B/D/F/H/J/L/N/P/R/T/V/X	1-248	[»]
2C37	X-ray	2.80	B/D/F/H/J/L/N/P/R/T/V/X	1-248	[»]
2C38	X-ray	3.10	B/D/F/H/J/L/N/P/R/T/V/X	1-248	[»]
2C39	X-ray	3.30	B/D/F/H/J/L/N/P/R/T/V/X	1-248	[»]
2JE6	X-ray	1.60	B	1-248	[»]
2JEA	X-ray	2.33	B	1-248	[»]
2JEB	X-ray	2.40	B	1-248	[»]
3L7Z	X-ray	2.41	B/E/H	4-248	[»]
4BA1	X-ray	1.80	B	1-248	[»]
4BA2	X-ray	2.50	B	1-248	[»]

ProteinModelPortal

Q9UXC2.

SMR

Q9UXC2. Positions 1-248.

ModBase

Search...

Protein-protein interaction databases

STRING

273057.SSO0735.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAK41031; AAK41031; SSO0735.

GeneID

1454998.

KEGG

sso:SSO0735.

Phylogenomic databases

eggNOG

COG0689.

HOGENOM

HOG000229515.

K11600.

OMA

DVFIEVL.

ProtClustDB

PRK03983.

Family and domain databases

HAMAP

MF_00591. Exosome_Exonucl_1.

InterPro

IPR011807. ExoRNase_exosome_complex.
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]

Pfam

PF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]

SUPFAM

SSF55666. 3_ExoRNase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.

TIGRFAMs

TIGR02065. ECX1. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q9UXC2.

Entry information

Entry name

ECX1_SULSO

Accession

Primary (citable) accession number: Q9UXC2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Other

Entry information

Relevant documents