Q9UX27 (Q9UX27_SULSF) Unreviewed, UniProtKB/TrEMBL
Last modified
January 25, 2012.
Version 79.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Amidophosphoribosyltransferase PIRNR PIRNR000485 Short name=ATase PIRNR PIRNR000485 EC=2.4.2.14 PIRNR PIRNR000485 Alternative name(s): Glutamine phosphoribosylpyrophosphate amidotransferase PIRNR PIRNR000485 | ||
| Gene names |
| ||
| Organism | Sulfolobus solfataricus EMBL CAB57667.1 | ||
| Taxonomic identifier | 2287 [NCBI] | ||
| Taxonomic lineage | Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus |
Protein attributes
| Sequence length | 404 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PIRNR PIRNR000485 |
| Cofactor | Binds 1 4Fe-4S cluster per subunit By similarity. PIRSR PIRSR000485-3 Binds 1 magnesium ion per subunit By similarity. PIRNR PIRNR000485 |
| Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. PIRNR PIRNR000485 |
| Sequence similarities | In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. PIRNR PIRNR000485 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Purine biosynthesis PIRNR PIRNR000485 |
| Ligand | Iron Iron-sulfur PIRSR PIRSR000485-3 Magnesium PIRNR PIRNR000485 Metal-binding |
| Molecular function | Glycosyltransferase PIRNR PIRNR000485 EMBL CAB57667.1 Transferase |
| Gene Ontology (GO) | |
| Biological process | nucleoside metabolic process Inferred from electronic annotation. Source: InterPro purine base biosynthetic processInferred from electronic annotation. Source: InterPro purine nucleotide biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | amidophosphoribosyltransferase activity Inferred from electronic annotation. Source: EC iron-sulfur cluster bindingInferred from electronic annotation. Source: UniProtKB-KW metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Metal binding | 199 | 1 | Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3 | ||||||
| Metal binding | 345 | 1 | Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3 | ||||||
| Metal binding | 394 | 1 | Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3 | ||||||
| Metal binding | 397 | 1 | Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3 | ||||||
Sequences
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References
| [1] | "Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2." Charlebois R.L., Singh R.K., Chan-Weiher C.C.-Y., Allard G., Chow C., Confalonieri F., Curtis B., Duguet M., Erauso G., Faguy D., Gaasterland T., Garrett R.A., Gordon P., Jeffries A.C., Kozera C., Kushwaha N., Lafleur E., Medina N. Sensen C.W.Genome 43:116-136(2000) [PubMed: 10701121] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: P2 EMBL CAB57667.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | Y18930 Genomic DNA. Translation: CAB57667.1. |
| PIR | G90210. |
| RefSeq | NP_342152.1. NC_002754.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1GPH based on UniProtKB P00497. |
| ProteinModelPortal | Q9UX27. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1454909. |
| NMPDR | fig|273057.1.peg.575. |
Phylogenomic databases | |
| HOGENOM | HBG392416. |
| OMA | FAIGYSK. |
| PhylomeDB | Q9UX27. |
| ProtClustDB | CLSK883660. |
Enzyme and pathway databases | |
| BioCyc | SSOL273057:SSO0633-MONOMER. |
Family and domain databases | |
| InterPro | IPR005854. Amd_phspho_trans. IPR017932. GATase_II. IPR000836. PRibTrfase. [Graphical view] |
| PANTHER | PTHR11907. Amd_phspho_trans. 1 hit. |
| Pfam | PF00156. Pribosyltran. 1 hit. [Graphical view] |
| PIRSF | PIRSF000485. Amd_phspho_trans. 1 hit. |
| PROSITE | PS51278. GATASE_TYPE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Q9UX27_SULSF | ||||||||
| Accession | Primary (citable) accession number: Q9UX27 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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