Q9UW25 (OBPA_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Oxysterol-binding protein-like protein OBPa

Gene names

Name:	OBPA
ORF Names:	CaO19.3198

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Miscellaneous	The C.albicans mating-type-like (MTL) locus contains, in addition to the genes for the regulatory proteins (MTLA1, MTLA2, MTLALPHA1 and MTLALPHA2), a and alpha idiomorphs of a phosphatidylinositol kinase (PIKA and PIKALPHA), a poly(A) polymerase (PAPA and PAPALPHA) and an oxysterol binding protein-like protein (OBPA and OBPALPHA).
Sequence similarities	Belongs to the OSBP family.

Ontologies

Keywords
Biological process	Lipid transport Transport
Ligand	Lipid-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	lipid transport Inferred from electronic annotation. Source: UniProtKB-KW pathogenesis Inferred from mutant phenotype PubMed 22253594. Source: CGD single-species biofilm formation on inanimate substrate Inferred from mutant phenotype PubMed 22253594. Source: CGD
Molecular_function	lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Oxysterol-binding protein-like protein OBPa		PRO_0000100383

Sequences

	Sequence		Length	Mass (Da)
	Q9UW25 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 9088364356E50FFF	FASTA	433	49,541
	10 20 30 40 50 60 MGLTSKLEKL KLKELTGHEA AVKSNVVNGA DTDDTDDIDE MDNEGQSILM GIIAQLRPGM 70 80 90 100 110 120 DLSRITLPTF ILEKKSMLER ITNFFQIPDM LLKANRTSDD VERFVSVLAW YLASWHIAPK 130 140 150 160 170 180 AVKKPLNPVL GETFNCYWEN ISDDCSAYYI SEQVSHHPPK SSYFYLVPEA KIKVDGILIP 190 200 210 220 230 240 KSRFLGNSSA AMMEGWAHLT LGEHENEVYE MNQPNVYCRG ILFGKMKMEL GDHMYVKCRK 250 260 270 280 290 300 TGLEADIDFK TKGFISGTYD AIEGVIKNSK TSEVLYQITG KWNEVMEIKD LKTGKKRVLV 310 320 330 340 350 360 DTKSSVPVKP RVRPLEEQGQ YESRKLWKPT IDALARRDHT VATEEKFAVE DEQRNLAKKR 370 380 390 400 410 420 IDDGVEFHPK FFRPVNEKEV ELQDLEYVIY KKFDLKSNPE VLTDEVLSIA PILPGQKHDE 430 KFEIPAFKKH EET

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans." Hull C.M., Johnson A.D. Science 285:1271-1275(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.
[2]	"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF167162 Genomic DNA. Translation: AAD51406.1. AACQ01000100 Genomic DNA. Translation: EAK95564.1.
RefSeq	XP_714614.1. XM_709521.1.
3D structure databases
ProteinModelPortal	Q9UW25.
ModBase	Search...
Protein-protein interaction databases
STRING	5476.CAL0002452.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3643764.
KEGG	cal:CaO19.3198.
Organism-specific databases
CGD	CAL0002452. OBPA.
Phylogenomic databases
eggNOG	NOG262374.
Family and domain databases
InterPro	IPR000648. Oxysterol-bd. IPR018494. Oxysterol-bd_CS. [Graphical view]
PANTHER	PTHR10972. PTHR10972. 1 hit.
Pfam	PF01237. Oxysterol_BP. 1 hit. [Graphical view]
PROSITE	PS01013. OSBP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OBPA_CANAL

Accession

Primary (citable) accession number: Q9UW25
Secondary accession number(s): Q59YI2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	May 1, 2000
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program