Reviewed, UniProtKB/Swiss-Prot Q9UVR2 (UBC1_MAGGR)

Names and origin

Protein names

Recommended name:
    Ubiquitin-conjugating enzyme E2-16 kDa
    EC=6.3.2.19
Alternative name(s):
    Ubiquitin-protein ligase
    Ubiquitin carrier protein

Gene names

Name:	UBC1
ORF Names:	MGG_06562

Organism

Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) [Complete proteome]

Taxonomic identifier

148305 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Magnaporthales › Magnaporthaceae › Magnaporthe

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the covalent attachment of ubiquitin to other proteins By similarity.
Catalytic activity	ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Pathway	Protein modification; protein ubiquitination.
Sequence similarities	Belongs to the ubiquitin-conjugating enzyme family.

Ontologies

Keywords
Biological process	Ubl conjugation pathway
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	modification-dependent protein catabolic process Inferred from electronic annotation. Source: UniProtKB-KW post-translational protein modification Inferred from electronic annotation. Source: InterPro regulation of protein metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin-protein ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 147	147	Ubiquitin-conjugating enzyme E2-16 kDa		PRO_0000082543
Sites
	Active site	107	1	Glycyl thioester intermediate By similarity
Experimental info
	Sequence conflict	128	1	K → R in AAD55983. Ref.1
	Sequence conflict	136	1	S → A in AAD55983. Ref.1
	Sequence conflict	143	1	R → P in AAD55983. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UVR2-1 [UniParc]. Last modified June 12, 2007. Version 2. Checksum: C7737C95FB7F61F7	FASTA	147	16,438
	10 20 30 40 50 60 MALKRINKEL TDLGRDPPSS CSAGPVGEDL FHWQATIMGP SDSPYAGGVF FLAIHFPTDY 70 80 90 100 110 120 PFKPPKVNFT TRIYHPNINS NGSICLDILR DQWSPALTIS KVLLSICSML TDPNPDDPLV 130 140 PEIAHVYKTA RAQYESTARE WTRKYAI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a ubiquitin-conjugating enzyme of the rice blast fungus Magnaporthe grisea." Kim Y.-K., Kolattukudy P.E. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The genome sequence of the rice blast fungus Magnaporthe grisea." Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K., Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D., Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S., Soanes D.M. , Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W. Nature 434:980-986(2005) [PubMed: 15846337] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 70-15 / FGSC 8958.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF161722 Genomic DNA. Translation: AAD55983.1. CH476833 Genomic DNA. Translation: EDK00488.1.
RefSeq	XP_370047.2.
UniGene	Mgr.10108
3D structure databases
HSSP	HSSP built from PDB template 1QCQ based on UniProtKB P15731.
SMR	Q9UVR2. Positions 1-147.
ModBase	Search...
Genome annotation databases
GeneID	2684717.
KEGG	mgr:MGG_06562.
Phylogenomic databases
OMA	Q9UVR2. NFTTRIY.
Enzyme and pathway databases
BRENDA	6.3.2.19. 5953.
Family and domain databases
InterPro	IPR016135. UBQ-conjugat/RWD-like. IPR000608. UBQ-conjugat_E2. [Graphical view]
Gene3D	G3DSA:3.10.110.10. UBQ-conjugat_E2. 1 hit.
Pfam	PF00179. UQ_con. 1 hit. [Graphical view]
ProDom	PD000461. UBQ_conjugat. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00212. UBCc. 1 hit. [Graphical view]
PROSITE	PS00183. UBIQUITIN_CONJUGAT_1. 1 hit. PS50127. UBIQUITIN_CONJUGAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBC1_MAGGR

Accession

Primary (citable) accession number: Q9UVR2
Secondary accession number(s): A4R868

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	June 12, 2007
Last modified:	June 16, 2009
This is version 49 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)