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Protein

60S acidic ribosomal protein P2

Gene

AFUA_2G10100

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plays an important role in the elongation step of protein synthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P2
Alternative name(s):
AfP2
Allergen: Asp f 8
Gene namesi
ORF Names:AFUA_2G10100
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiFungiDB:Afu2g10100.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3126. Asp f 8.0101.
78. Asp f 8.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11111160S acidic ribosomal protein P2PRO_0000157673Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei101 – 1011PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ9UUZ6.

Interactioni

Subunit structurei

P1 and P2 exist as dimers at the large ribosomal subunit.

Structurei

3D structure databases

ProteinModelPortaliQ9UUZ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L12P family.Curated

Phylogenomic databases

HOGENOMiHOG000229897.
InParanoidiQ9UUZ6.
KOiK02943.
OMAiTCPSAND.
OrthoDBiEOG708WC9.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch.
InterProiIPR027534. Ribosomal_L12.
IPR001859. T.cruzi_P2-like.
[Graphical view]
PRINTSiPR00456. RIBOSOMALP2.

Sequencei

Sequence statusi: Complete.

Q9UUZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHLAAYLLL ALAGNTSPSS EDVKAVLSSV GIDADEERLN KLIAELEGKD
60 70 80 90 100
LQELIAEGST KLASVPSGGA AAAAPAAAGA AAGGAAAPAA EEKKEEEKEE
110
SDEDMGFGLF D
Length:111
Mass (Da):11,141
Last modified:December 6, 2005 - v2
Checksum:i0B4C19B5CEE25471
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti3 – 31H → Y in CAB64688 (Ref. 1) Curated
Sequence conflicti7 – 71Y → F in CAB64688 (Ref. 1) Curated
Sequence conflicti91 – 911E → K in CAB64688 (Ref. 1) Curated
Sequence conflicti94 – 941K → N in CAB64688 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ224333 mRNA. Translation: CAB64688.1.
AF268870 Genomic DNA. Translation: AAG01801.1.
AAHF01000001 Genomic DNA. Translation: EAL93305.1.
RefSeqiXP_755343.1. XM_750250.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00004605; CADAFUAP00004605; CADAFUAG00004605.
GeneIDi3512932.
KEGGiafm:AFUA_2G10100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ224333 mRNA. Translation: CAB64688.1.
AF268870 Genomic DNA. Translation: AAG01801.1.
AAHF01000001 Genomic DNA. Translation: EAL93305.1.
RefSeqiXP_755343.1. XM_750250.1.

3D structure databases

ProteinModelPortaliQ9UUZ6.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3126. Asp f 8.0101.
78. Asp f 8.

Proteomic databases

PRIDEiQ9UUZ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00004605; CADAFUAP00004605; CADAFUAG00004605.
GeneIDi3512932.
KEGGiafm:AFUA_2G10100.

Organism-specific databases

EuPathDBiFungiDB:Afu2g10100.

Phylogenomic databases

HOGENOMiHOG000229897.
InParanoidiQ9UUZ6.
KOiK02943.
OMAiTCPSAND.
OrthoDBiEOG708WC9.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch.
InterProiIPR027534. Ribosomal_L12.
IPR001859. T.cruzi_P2-like.
[Graphical view]
PRINTSiPR00456. RIBOSOMALP2.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Highly conserved ribosomal proteins binding to serum IgE of Aspergillus fumigatus sensitized individuals."
    Hemmann S., Crameri R.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: ATCC 42202 / AF-102 / Ag 507.
  2. "Role of the ribosomal stalk components in the resistance of Aspergillus fumigatus to the sordarin antifungals."
    Santos C., Ballesta J.P.G.
    Mol. Microbiol. 43:227-237(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
    Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.
    , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.
    Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Entry informationi

Entry nameiRLA2_ASPFU
AccessioniPrimary (citable) accession number: Q9UUZ6
Secondary accession number(s): Q4X1G0, Q9HGU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: December 6, 2005
Last modified: November 11, 2015
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.