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Q9UUI7 (TPSY_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit

EC=2.4.1.15
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene names
ORF Names:SPAC22F8.05
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length891 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

Sequence similarities

In the N-terminal section; belongs to the glycosyltransferase 20 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 891891Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit
PRO_0000122513

Regions

Region132 – 613482Glycosyltransferase

Amino acid modifications

Modified residue881Phosphothreonine Ref.2
Modified residue1081Phosphoserine Ref.2
Modified residue1091Phosphoserine Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9UUI7 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 7F74688CCBFC45B9

FASTA891100,661
        10         20         30         40         50         60 
MGRQFICSIY LPYTINFHLD ELEGNHESHP AITHQEKVTQ THRDSVKIDD ILTRLSISKS 

        70         80         90        100        110        120 
ESGQATPVLT PQLEGMNDYF SLGPSKRTGG SMTPGLGAMS PIPGSGRSSP LYTQPRSRAT 

       130        140        150        160        170        180 
SPSRVRQADR FAAPGIGAGA LPIRRKRRDS LAKSVALFES ARWSVERGVV GNSGLFHAVD 

       190        200        210        220        230        240 
AAVRDHGLQN PLWVGLLGMP TESLSEKTKN AISGALLVKH QSLVVYTSDS NFEGHYNHYC 

       250        260        270        280        290        300 
RKILWPSLHY QHNEIFSFFH EESNWDDYVA VNRAFADALI KNYKTGDTIW VNDYHLLLVP 

       310        320        330        340        350        360 
NMVRERIPSA IIGLFIHVSF PSSEVFRCFA RRKELLQGML GSNLIGFQTE EYKRHFLQSC 

       370        380        390        400        410        420 
SRVLYAESTF DRILLDDRYI DVYAHPIGAD PVLVDKWLEN PETLEVKEVL EKRYANLNIF 

       430        440        450        460        470        480 
VGCDKMDPIR GIREKLLAFE QFLYDNPEYQ KNTILIQTST FTEEQKEYGV AISDIVTRIN 

       490        500        510        520        530        540 
SAFGDFSLDH LPVTILSSDL SYPQYLALLS VADAFIVTSL REGMSLTCHE FILTQRQKKS 

       550        560        570        580        590        600 
PLIVSEFIGC ASMFSNGAFI VNPWSTLELS LSMKKALTLS TNERNQRYSN CLDVVLTHSA 

       610        620        630        640        650        660 
SNWVTGFETK LKKSWTSQQK RDFSRLPRFT LNFIGNRYDH AKKRLLILNF DGNAVTWEGR 

       670        680        690        700        710        720 
HEFVDFHYGY MVSILSKLIA DDRNIVYIAS CLEEDELESL FMHVPGVGLI AENGCYVLPH 

       730        740        750        760        770        780 
YAENVHQSWI RLYKKQQMDW REPLHDIIQY YSERTPGSSL IDHGFAMEFN YVKAENRENG 

       790        800        810        820        830        840 
LRSAGELASS INETQHGCRA VPLDGRVLCE PTTISKATAA NYIMTHLIKN PEELDLILVA 

       850        860        870        880        890 
GNNRTDESVF AWANKSKVSS FTVSMGVGNT EAKAYTDGIP SFFNVLNSLC A 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-88; SER-108 AND SER-109, IDENTIFICATION BY MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB52715.1.
PIRT38195.
RefSeqNP_594728.1. NM_001020156.2.

3D structure databases

ProteinModelPortalQ9UUI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278393. 30 interactions.
MINTMINT-4714293.
STRING4896.SPAC22F8.05-1.

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Proteomic databases

MaxQBQ9UUI7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC22F8.05.1; SPAC22F8.05.1:pep; SPAC22F8.05.
GeneID2541903.
KEGGspo:SPAC22F8.05.

Organism-specific databases

PomBaseSPAC22F8.05.

Phylogenomic databases

eggNOGCOG0380.
HOGENOMHOG000179930.
KOK16055.
OMAATNEGLQ.
OrthoDBEOG76QFS6.
PhylomeDBQ9UUI7.

Family and domain databases

Gene3D3.40.50.1000. 2 hits.
InterProIPR001830. Glyco_trans_20.
IPR023214. HAD-like_dom.
IPR003337. Trehalose_PPase.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
PF02358. Trehalose_PPase. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
ProtoNetSearch...

Other

NextBio20802990.

Entry information

Entry nameTPSY_SCHPO
AccessionPrimary (citable) accession number: Q9UUI7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names