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Protein

Ribosome production factor 2 homolog

Gene

SPAC926.08c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome production factor 2 homolog
Alternative name(s):
Brix domain-containing protein 1 homolog
Ribosome biogenesis protein RPF2 homolog
Gene namesi
ORF Names:SPAC926.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC926.08c.
PomBaseiSPAC926.08c.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleolus Source: PomBase
  • nucleus Source: PomBase
  • small nucleolar ribonucleoprotein complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317Ribosome production factor 2 homologPRO_0000120229Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei293 – 2931Phosphoserine1 Publication
Modified residuei300 – 3001Phosphoserine1 Publication
Modified residuei313 – 3131Phosphoserine1 Publication
Modified residuei316 – 3161Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9UUG1.

PTM databases

iPTMnetiQ9UUG1.

Interactioni

Protein-protein interaction databases

BioGridi279918. 10 interactions.
MINTiMINT-4713256.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 240213BrixPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RPF2 family.Curated
Contains 1 Brix domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000157782.
InParanoidiQ9UUG1.
KOiK14847.
OMAiGQKTPRI.
OrthoDBiEOG7P2Z35.
PhylomeDBiQ9UUG1.

Family and domain databases

InterProiIPR007109. Brix.
[Graphical view]
PfamiPF04427. Brix. 1 hit.
[Graphical view]
SMARTiSM00879. Brix. 1 hit.
[Graphical view]
PROSITEiPS50833. BRIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UUG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRQVKPKNA RTKRALEKRE PKLVEGAKTA IFLRGNATSQ ISLDVLGDIH
60 70 80 90 100
ALKKPFSVNF QKKNNILPFE DASSLEFFSE KNDAALAVMA THNKKRPHNL
110 120 130 140 150
TWVRFFNYRV LDMIELGIVN YKSIQSFSAT PIVPGTKPMI LFQGPVFDAH
160 170 180 190 200
PTYRHIKSLF LDFFRGEPIQ KLDSAGLSYV IVVSAAEAQE DETKPLPLVH
210 220 230 240 250
FRVYGTKLLK TKTNLPRVEL EEMGPRIDFN IRRVQPAESD VLEEALKKPK
260 270 280 290 300
TQEPKPKKNV DVDIIGNKVG RIHVDQQDLG NLQTRKMKGL KRSVEEREDS
310
ENEEVEIEED VISDASE
Length:317
Mass (Da):36,071
Last modified:May 1, 2000 - v1
Checksum:i0438CA22A431DCF2
GO

Sequence cautioni

The sequence BAA87188.1 differs from that shown. Reason: Frameshift at position 128. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB54156.1.
AB027884 Genomic DNA. Translation: BAA87188.1. Frameshift.
PIRiT39206.
RefSeqiNP_594369.1. NM_001019790.2.

Genome annotation databases

EnsemblFungiiSPAC926.08c.1; SPAC926.08c.1:pep; SPAC926.08c.
GeneIDi2543500.
KEGGispo:SPAC926.08c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB54156.1.
AB027884 Genomic DNA. Translation: BAA87188.1. Frameshift.
PIRiT39206.
RefSeqiNP_594369.1. NM_001019790.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279918. 10 interactions.
MINTiMINT-4713256.

PTM databases

iPTMnetiQ9UUG1.

Proteomic databases

MaxQBiQ9UUG1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC926.08c.1; SPAC926.08c.1:pep; SPAC926.08c.
GeneIDi2543500.
KEGGispo:SPAC926.08c.

Organism-specific databases

EuPathDBiFungiDB:SPAC926.08c.
PomBaseiSPAC926.08c.

Phylogenomic databases

HOGENOMiHOG000157782.
InParanoidiQ9UUG1.
KOiK14847.
OMAiGQKTPRI.
OrthoDBiEOG7P2Z35.
PhylomeDBiQ9UUG1.

Miscellaneous databases

PROiQ9UUG1.

Family and domain databases

InterProiIPR007109. Brix.
[Graphical view]
PfamiPF04427. Brix. 1 hit.
[Graphical view]
SMARTiSM00879. Brix. 1 hit.
[Graphical view]
PROSITEiPS50833. BRIX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
    Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
    Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 100-278, SUBCELLULAR LOCATION.
    Strain: ATCC 38364 / 968.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-293; SER-300; SER-313 AND SER-316, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiRPF2_SCHPO
AccessioniPrimary (citable) accession number: Q9UUG1
Secondary accession number(s): Q9UU08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: May 1, 2000
Last modified: July 6, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.