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Protein

Probable tyrosine-protein phosphatase C17A3.03c

Gene

pi043

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotationBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei189Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein phosphatase C17A3.03c (EC:3.1.3.48)
Gene namesi
ORF Names:pi043, SPBC17A3.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC17A3.03c.
PomBaseiSPBC17A3.03c.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003159351 – 287Probable tyrosine-protein phosphatase C17A3.03cAdd BLAST287

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei156Phosphoserine1 Publication1
Modified residuei159Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9UUF3.
PRIDEiQ9UUF3.

PTM databases

iPTMnetiQ9UUF3.

Interactioni

Protein-protein interaction databases

BioGridi276671. 32 interactors.
MINTiMINT-4713021.

Family & Domainsi

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family.Sequence analysis

Phylogenomic databases

InParanoidiQ9UUF3.
KOiK18045.
OrthoDBiEOG092C4JKC.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UUF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIVFPFQLE KKLISITSDR DQISMSIPEV SSHDSCLNDC HSVNSEEQAK
60 70 80 90 100
PVCCLELNAH KDGIKVVDTS NDASTFSNSP LVPDNFGVVY PGIIYRSACP
110 120 130 140 150
RASNFNFLES LHIRTIISLR QEEYSEEDLH YFTKHHINYY HIAMPGSKHR
160 170 180 190 200
KNDCISSSSN PDISDVDDLV RKTLQLLLNK ENWPVLLHCS RGKHRTGIVI
210 220 230 240 250
GCLRALMNWP VGNRLQEYIS FSHPKEREVD EEYIQNFSSD PSLKSSLNDL
260 270 280
KRYISDSSSE LADVVLSSES PTVQAATVNE TCRSPGS
Length:287
Mass (Da):32,291
Last modified:July 11, 2012 - v3
Checksum:iD261498B24DE12AA
GO

Sequence cautioni

The sequence BAA21423 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004537 Genomic DNA. Translation: BAA21423.1. Sequence problems.
CU329671 Genomic DNA. Translation: CAB51762.2.
PIRiT39695.
RefSeqiNP_595585.2. NM_001021481.2.

Genome annotation databases

EnsemblFungiiSPBC17A3.03c.1; SPBC17A3.03c.1:pep; SPBC17A3.03c.
GeneIDi2540134.
KEGGispo:SPBC17A3.03c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004537 Genomic DNA. Translation: BAA21423.1. Sequence problems.
CU329671 Genomic DNA. Translation: CAB51762.2.
PIRiT39695.
RefSeqiNP_595585.2. NM_001021481.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276671. 32 interactors.
MINTiMINT-4713021.

PTM databases

iPTMnetiQ9UUF3.

Proteomic databases

MaxQBiQ9UUF3.
PRIDEiQ9UUF3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC17A3.03c.1; SPBC17A3.03c.1:pep; SPBC17A3.03c.
GeneIDi2540134.
KEGGispo:SPBC17A3.03c.

Organism-specific databases

EuPathDBiFungiDB:SPBC17A3.03c.
PomBaseiSPBC17A3.03c.

Phylogenomic databases

InParanoidiQ9UUF3.
KOiK18045.
OrthoDBiEOG092C4JKC.

Miscellaneous databases

PROiQ9UUF3.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYNF3_SCHPO
AccessioniPrimary (citable) accession number: Q9UUF3
Secondary accession number(s): O13635
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2012
Last modified: November 30, 2016
This is version 88 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.